1.1.3.9 2,2'-dipyridyl 1 mM, 67% inhibition 375 1.1.3.9 2,4,6-Trinitrobenzenesulfonic acid 53% inhibition at 1 mM 3774 1.1.3.9 2-deoxy-D-galactose competitive inhibition 2006 1.1.3.9 2-mercaptoethanol 43% inhibition at 1 mM 63 1.1.3.9 2-mercaptoethanol - 63 1.1.3.9 8-hydroxyquinoline 1 mM, 50% inhibition 321 1.1.3.9 AgNO3 complete inhibition at 0.1 mM 360 1.1.3.9 CN- intracellular enzyme, 37% inhibition at 0.01 mM 159 1.1.3.9 CN- inhibition at 0.1 mM 159 1.1.3.9 Co2+ 1 mM, 50% inhibition 23 1.1.3.9 CTAB 5 mM, 77% of initial activity 21954 1.1.3.9 D-galactono-1,4-lactone 23.7% inhibition at 0.25 mM 2730 1.1.3.9 D-galactosamine competitive inhibition 3997 1.1.3.9 D-galacturonic acid 66.8% inhibition at 0.25 mM 1968 1.1.3.9 diethyldithiocarbamate intracellular enzyme, 87% inhibition at 0.005 mM 373 1.1.3.9 diethyldithiocarbamate 61% inhibition at 0.01 mM 373 1.1.3.9 diethyldithiocarbamate - 373 1.1.3.9 diethyldithiocarbamate inhibition at 0.1 mM 373 1.1.3.9 dithiothreitol 40% inhibition at 1 mM 45 1.1.3.9 EDTA 1 mM, 34% inhibition 21 1.1.3.9 EDTA inhibits the formation of the thioether bond under anaerobic conditions (posttranslational modification) 21 1.1.3.9 EDTA 56% inhibition 21 1.1.3.9 EDTA 5 mM, 81% of initial activity 21 1.1.3.9 Fe2+ 1 mM, 17% inhibition 25 1.1.3.9 ferricyanide inhibition at 0.001 mM, activation at 1 mM 132 1.1.3.9 ganglioside bovine brain and Tay-Sachs disease gangliosides: competitive inhibition 9171 1.1.3.9 GSH complete inhibition at 10 mM 142 1.1.3.9 H2O2 42% inhibition at 2 mM 22 1.1.3.9 H2O2 complete inhibition at 10 mM 22 1.1.3.9 H2O2 irreversible inactivation, only during active catalysis 22 1.1.3.9 H2O2 high concentrations of hydrogen peroxide inactivate GAO, catalase can be added to the reaction mixture to degrade H2O2 and prolong GAO activity 22 1.1.3.9 H2O2 high concentrations of hydrogen peroxide inactivate GAO, catalase can be added to the reaction mixture to degrade H2O2 and prolong GAO activity; high concentrations of hydrogen peroxide inactivate GAO, catalase can be added to the reaction mixture to degrade H2O2 and prolong GAO activity 22 1.1.3.9 hydrazine 1 mM, 41% inhibition 684 1.1.3.9 hydroxylamine intracellular enzyme, 47% inhibition at 0.1 mM 85 1.1.3.9 hydroxylamine 1 mM, 31% inhibition 85 1.1.3.9 iodoacetamide 22% inhibition at 0.1 mM 67 1.1.3.9 iodoacetamide 35% inhibition at 0.1 mM 67 1.1.3.9 iodoacetamide 95% inactivation 67 1.1.3.9 iodoacetic acid slight inactivation 213 1.1.3.9 KCl 5 mM, 90% of initial activity 79 1.1.3.9 KCN complete inhibition 161 1.1.3.9 L-ascorbic acid 58% inhibition at 0.1 mM 974 1.1.3.9 Mg2+ 1 mM, 50% inhibition 6 1.1.3.9 Monoiodoacetic acid 1 mM, 40% inhibition 2275 1.1.3.9 additional information no inhibition: EDTA, Tween 80, NH4+, Na+, Mg2+, K+, and glycerol 2 1.1.3.9 additional information in both active and inactive forms, protein monomer integrity is lost with a single radiation interaction anywhere in the polypeptide, but enzymatic activity is more resistant, yielding target sizes considerably smaller than that of the monomer 2 1.1.3.9 N-acetylgalactosamine competitive inhibition 2147 1.1.3.9 N-bromosuccinimide complete inhibition at 1 mM 208 1.1.3.9 N-bromosuccinimide complete inactivation by oxidation of active center tryptophan 208 1.1.3.9 NaCl 5 mM, 90% of initial activity 42 1.1.3.9 NaN3 54% inhibition at 0.1 mM 238 1.1.3.9 NaN3 68% inhibition at 0.1 mM 238 1.1.3.9 NaN3 complete inhibition 238 1.1.3.9 NH2OH complete inhibition at 0.1 mM 1109 1.1.3.9 Ni2+ 1 mM, 50% inhibition 38 1.1.3.9 o-phenanthroline 18.6% inhibition at 1 mM 239 1.1.3.9 o-phenanthroline 1 mM, 19% inhibition 239 1.1.3.9 p-chloromercuribenzoate 22% inhibition at 0.1 mM 43 1.1.3.9 phenylhydrazine 1 mM, 91% inhibition 398 1.1.3.9 SDS - 124 1.1.3.9 SDS 5 mM, 4% of initial activity 124 1.1.3.9 Semicarbazide 1 mM, 44% inhibition 382 1.1.3.9 Sodium dithionite 73% inhibition at 0.1 mM 3230 1.1.3.9 Superoxide dismutase 50% inhibition at 50 pM 3868 1.1.3.9 trans-(2)-phenylcyclopropylcarbinol mechanism-based inactivator 55888 1.1.3.9 Zn2+ 1 mM, 33% inhibition 14