1.1.1.53 16alpha-Bromoacetoxyprogesterone - 29302 1.1.1.53 17-Acetoxyprogesterone - 90700 1.1.1.53 17-Bromoacetoxyprogesterone - 90702 1.1.1.53 17beta-Bromoacetoxyandrostan-3-one - 90725 1.1.1.53 20beta-Hydroxycortisol - 91215 1.1.1.53 20beta-hydroxyprogesterone - 19953 1.1.1.53 5alpha-Dihydrotestosterone bromoacetate - 91984 1.1.1.53 amiloride Na+/H+-exchanger inhibitor 5517 1.1.1.53 apigenin significant inhibition at 0.1 mM 515 1.1.1.53 carbenoxolone - 1844 1.1.1.53 Cd2+ - 52 1.1.1.53 Cortisone 21-iodoacetate in absence of NADH, slight 92966 1.1.1.53 Cu2+ - 19 1.1.1.53 cycloheximide - 1715 1.1.1.53 cysteine slight 153 1.1.1.53 diclofenac 100 microM reduces carbonyl reductase activity by 66% 1291 1.1.1.53 dithiothreitol slight 45 1.1.1.53 Fe2+ - 25 1.1.1.53 glycyrrhizic acid - 5309 1.1.1.53 Hg2+ - 33 1.1.1.53 indomethacin 10 microM reduces carbonyl reductase activity by 69% 546 1.1.1.53 additional information substrate and product inhibition 2 1.1.1.53 additional information no inhibition with iodoacetate, acetylsialic acid, phenylmethylsulfonyl fluoride, glyoxal, iodoacetamide, dimethylaminoisopropyl ethylene dicarbodiimide, acetylimidazol, diethyl pyrocarbonate 2 1.1.1.53 Phenylbutazone 50 microM reduces carbonyl reductase activity by 51% 4043 1.1.1.53 pyridoxal 5'-phosphate slightly 32 1.1.1.53 Tetranitromethane other Tyr-selective reagents, Tyr residues are labeled with nitro-group by inhibitor 1453