1.1.1.346 Cu2+ strong inhibition at 0.5 mM 19 1.1.1.346 Fe3+ strong inhibition at 0.5 mM 70 1.1.1.346 additional information not inhibited by 2-dehydro-L-gulonate. There is no observed effect on activity by 0.5 mM solutions of Mg2+, Mn2+, Ca2+, or Co2+, 14 mM 2-mercaptoethanol, 1 mM dithiothreitol, or 1 mM EDTA 2 1.1.1.346 NADP+ competitive inhibition 10 1.1.1.346 Ni2+ strong inhibition at 0.5 mM 38 1.1.1.346 Zn2+ strong inhibition at 0.5 mM 14