2.1.1.157	4-chloromercuribenzoate	recombinant enzyme: 23% inhibition at 1.33 mM, completely reversible by 5.3 mM DTT	388	
2.1.1.157	betaine	recombinant enzyme: poor inhibition, 71% inhibition at 2 M with sarcosine, and 69% inhibition at 2 M with dimethylglycine, partially reversible by salts KCl and NaCl, overview	713	
2.1.1.157	betaine	above 1.0 M, no effect on sarcosine N-methyltransferase activity, 35% inhibition of N,N-dimethylglycine N-methyltransferase activity	713	
2.1.1.157	betaine	does not affect the SMT activity, but represses the DMT activity by 35% at 2 M	713	
2.1.1.157	dimethylglycine	competitive inhibition, versus sarcosine, 40% inhibition at 250 mM	4239	
2.1.1.157	isovaleric acid	10% inhibition at 250 mM, with dimethylglycine	13186	
2.1.1.157	KCl/NaCl	recombinant enzyme: 32% inhibition at 0.33 M KCl and 0.66 M NaCl with sarcosine, and 25% inhibition at 0.33 M KCl and 0.66 M NaCl with dimethylglycine, decrease inhibition by betaine, overview	56884	
2.1.1.157	L-alanine	10% inhibition at 250 mM, with dimethylglycine	103	
2.1.1.157	L-cysteine	10% inhibition at 250 mM, with dimethylglycine	74	
2.1.1.157	L-methionine	10% inhibition at 250 mM, with dimethylglycine	88	
2.1.1.157	L-phenylalanine	10% inhibition at 250 mM	104	
2.1.1.157	additional information	no inhibition by N,N-dimethylglycine	2	
2.1.1.157	additional information	inhibition rates with sarcosine, overview, no inhibition with dimethylglycine by glycine, acetate, ethanolamine, monomethylethanolamine, serine, asparagine, glutamate, and proline	2	
2.1.1.157	additional information	potassium or sodium ions at 200-1000 mM affect neither sarcosine N-methyltransferase activity nor dimethylglycine N-methyltransferase activity	2	
2.1.1.157	additional information	both the SMT and DMT activities of SDMT from halophilic methanoarchaea are not inhibited by KCl or NaCl	2	
2.1.1.157	n-butyric acid	50% inhibition at 250 mM, with dimethylglycine	3528	
2.1.1.157	propionic acid	10% inhibition at 250 mM, with dimethylglycine	1724	
2.1.1.157	S-adenosyl-L-homocysteine	recombinant enzyme: competitive product inhibition, 50% inhibition at 0.5 mM with glycine, and at 2.3 mM with sarcosine	36	
2.1.1.157	S-adenosyl-L-homocysteine	product inhibition	36	
2.1.1.157	S-adenosyl-L-homocysteine	0.2 mM, 63% loss of sarcosine N-methyltransferase activity, 81% loss of dimethylglycine N-methyltransferase activity. At 1 mM, complete loss of sarcosine N-methyltransferase activity, 88% loss of dimethylglycine N-methyltransferase activity	36	
2.1.1.157	sarcosine	slight competitive inhibition, versus dimethylglycine, 20% inhibition at 250 mM	594	
2.1.1.157	tert-butylacetic acid	30% inhibition at 250 mM, with dimethylglycine	125060