1.21.1.1 2',3,4',5,6'-pentachlorobiphenyl-4-ol - 205175 1.21.1.1 2',3,4',6'-tetrachlorobiphenyl-4-ol - 205176 1.21.1.1 2,2',5,5'-tetrachlorobiphenyl-4-ol - 205177 1.21.1.1 2,2'-dipyridyl - 375 1.21.1.1 2,3,6-tribromo-4-(2,4-dibromophenoxy)phenol - 204879 1.21.1.1 2,3-dibromo-4-(2,4-dibromophenoxy)phenol - 204880 1.21.1.1 2,5-dibromo-4-(2,4-dibromophenoxy)phenol - 204883 1.21.1.1 3,5-diiodo-L-tyrosine pronounced substrate inhibition above 5 microM 3597 1.21.1.1 3-bromo-4-(2,4-dibromophenoxy)phenol - 205070 1.21.1.1 3-hydroxy-2,2',5,5'-tetrachlorobiphenyl - 205072 1.21.1.1 4'-hydroxy-2,2',4,5'-tetrabromodiphenyl ether - 194350 1.21.1.1 4'-hydroxy-2,2',4-tribromodiphenyl ether - 194348 1.21.1.1 4,4'-dihydroxy-3,3',5,5'-tetrachlorobiphenyl - 205110 1.21.1.1 4-hydroxy-2',3,4',5,6'-pentachlorobiphenyl - 136165 1.21.1.1 4-hydroxy-2,2',3,4',5-pentabromodiphenyl ether - 194351 1.21.1.1 4-hydroxy-2,3,3',4'-tetrabromodiphenyl ether - 194349 1.21.1.1 5-bromo-2-(2,4-dibromophenoxy)phenol - 205284 1.21.1.1 5-bromo-2-(4-bromophenoxy)phenol - 205285 1.21.1.1 benzbromarone - 9775 1.21.1.1 bithionol - 2724 1.21.1.1 bromoxynil - 32163 1.21.1.1 closantel - 20682 1.21.1.1 erythrosine B - 21597 1.21.1.1 additional information among polychlorinated biphenyls and polybrominated diphenyl ethers without a hydroxyl group tested, including their methoxylated metabolites, none is inhibitory 2 1.21.1.1 additional information target for disruption of thyroid hormone homeostasis by environmental halogenated chemicals, e.g. food colorants, pharmaceuticals, agrochemicals, and antiparasitics, effects of environmental halogenated chemicals on iodotyrosine deiodinase activity, overview. Non-hydroxylated PCBs (e.g., 2,2',4,4'-tetrachlorobiphenyl) and PBDEs (e.g., 2,2',4,4'-tetrabromodiphenyl ether), nitrofen, trichlabendazole, miconazole and amiodarone lack IYD-inhibitory activity 2 1.21.1.1 N-ethylmaleimide - 49 1.21.1.1 nitroxynil - 205834 1.21.1.1 o-phenanthroline - 239 1.21.1.1 oxyclozanide - 205838 1.21.1.1 phloxine B - 40360 1.21.1.1 Rose bengal most potent inhibitor tested 1331 1.21.1.1 Rose bengal - 1331 1.21.1.1 tribromsalan - 205854 1.21.1.1 triclosan - 744