3.4.24.79 IGF - 638941 3.4.24.79 IGF PAPP-A activity is dependent on presence of insulin-like growth factor 638944 3.4.24.79 IGF PAPP-A activity is dependent on presence of insulin-like growth factor-II 638938, 638940 3.4.24.79 IGF-I the rate of IGFBP-4 proteolysis is dramatically increased upon addition of IGF-I or -II with IGF-II being more potent than IGF-I, while IGFBP-5 cleavage is slightly inhibited, the mechanism of IGF-modulated proteolysis of IGFBP-4 and -5 involves changes in both the recognition of substrate and the turnover rate, overview 683161 3.4.24.79 IGF-II the rate of IGFBP-4 proteolysis is dramatically increased upon addition of IGF-I or -II with IGF-II being more potent than IGF-I, while IGFBP-5 cleavage is slightly inhibited, the mechanism of IGF-modulated proteolysis of IGFBP-4 and -5 involves changes in both the recognition of substrate and the turnover rate, overview 683161 3.4.24.79 additional information follicle stimulating hormone and 17beta-estradiol stimulate PAPP-A expression in granulosa cells, overview 683873 3.4.24.79 additional information the enzyme expression in fibroblasts is stimulated by pro-inflammatory cytokines involved in repair responses, especially TNFalpha and interleukin 1-beta, the stimulation is inhibited by resveratrol 683504