3.4.21.27	activated factor IX	autoactivation, cleavage of FXI at the Arg369-Ile370 bond. activated factor IX is part of a feedback loop that sustains thrombin generation through FIX activation to consolidate coagulation	707856	
3.4.21.27	activated factor VII	-	707308	
3.4.21.27	activated factor XI	-	709721	
3.4.21.27	activated factor XII	activated factor XII-mediated activation of FXI appears to play a central role in formation of pathologic thrombi in murine thrombosis models	707856	
3.4.21.27	activated factor XII	activates its substrate FXI	709722	
3.4.21.27	activated factor XII	cleaves FXI at the Arg369-Ile370 bond	707856	
3.4.21.27	activated factor XII	FXI activation proceeds through an intermediate with only one activated submit	709721	
3.4.21.27	alpha-thrombin	cleaves FXI at the Arg369-Ile370 bond	707856	
3.4.21.27	desmopressin	-	707308	
3.4.21.27	desmopressin	increase of both FXI activity (up to 31%) and antigen levels 60 min after infusion. Also contradictory results with a lack of rise of FXI levels after infusion	707148