5.3.3.2 2-mercaptoethanol activates 2936 5.3.3.2 dithiothreitol activates 2936, 2941 5.3.3.2 glutathione activates 2936 5.3.3.2 L-Cysteine hydrochloride activates 2936 5.3.3.2 mevalonic acid activates 2936 5.3.3.2 Mevalonic acid lactone weakly activates 2936 5.3.3.2 2-mercaptoethanol activates isomerase III and IV 2937 5.3.3.2 FMN required as cofactor. The enzyme requires the combined presence of FMN, NADPH and Mg2+ 651733 5.3.3.2 NADPH required as cofactor. The enzyme requires the combined presence of FMN, NADPH and Mg2+ 651733