2.8.2.20 5'-AMP increases product formation 10fold by preventing degradation of 3'-phosphoadenylylsulfate 645805 2.8.2.20 5'-AMP optimal concentration 2 mM 645820 2.8.2.20 6-keto-prostaglandin F1alpha 23% activation at 0.1 mM 645821 2.8.2.20 CHAPS activation, 0.5% w/v 645805 2.8.2.20 dithiothreitol 1 mM 645820 2.8.2.20 Lubrol Px 3fold stimulation at 0.1% w/v, weak inhibition above 0.1% w/v 645805 2.8.2.20 Lubrol Px activation 645805, 645815 2.8.2.20 lysophosphatidylcholine slight activation, 0.2 mM 645807 2.8.2.20 Mg2+ strongly stimulates isozyme TPST-2, but not TPST-1 705836 2.8.2.20 Mn2+ strong activation of both isozymes 705836 2.8.2.20 additional information no activation by arachidonic acid 645821 2.8.2.20 additional information no activation by octyl glucoside 645805 2.8.2.20 additional information no stimulation by 5'-AMP, NaF and Triton X-100 645826 2.8.2.20 additional information stimulation by ethanol involves increased TPST level rather than change in affinity for its substrates 645819, 645825 2.8.2.20 Nonidet P-40 6fold stimulation at 0.5% 645820 2.8.2.20 Nonidet P-40 activation, 0.5% w/v 645805 2.8.2.20 oleic acid activation, 0.2 mM 645807 2.8.2.20 phosphatidylinositol slight activation, 0.2 mM 645807 2.8.2.20 phosphatidylserine slight activation, 0.2 mM 645807 2.8.2.20 prostaglandin E2 1.5fold stimulation at 0.1 mM, half maximal stimulation at 0.05 mM 645821 2.8.2.20 prostaglandin F2alpha 22% activation at 0.1 mM 645821 2.8.2.20 sodium dodecylsulfate 2fold stimulation at 0.1% 645820 2.8.2.20 Sofalcone 55% stimulation 645820 2.8.2.20 Triton X-100 6fold stimulation at 0.5% 645820 2.8.2.20 Triton X-100 activation 645805, 645815 2.8.2.20 Triton X-100 microsomal membrane-bound enzyme, not solubilized enzyme 645804 2.8.2.20 Triton X-100 requirement 645804 2.8.2.20 Triton X-100 sulfation of poly-EAY, but not of tert-butoxycarbonylcholecystokinin 645804 2.8.2.20 Tween 20 6fold stimulation at 0.5% 645820 2.8.2.20 Tween 20 activation, 0.5% w/v 645805 2.8.2.20 Tween 80 activation, 0.5% w/v 645805 2.8.2.20 vemurafenib complete inhibition of TPST1 at 0.4 mM, vemurafenib potentially induces partial TPST-1 activation at lower concentrations, inhibiting the activity at higher concentrations 760527