2.7.6.5	dCDP	slightly stimulates synthesis of guanosine 3'-diphosphate 5'-triphosphate, inhibits polynucleotide phosphorylase activities of enzyme	642777	
2.7.6.5	ethanol	little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%	642773	
2.7.6.5	guanosine-5',3'-dibisphosphate	ppGpp, potential allosteric regulator, activates the enzyme with an EC50 of 0.060 mM	737883	
2.7.6.5	methanol	maximal stimulation of GPSI by 20% v/v	642775	
2.7.6.5	additional information	(p)ppGpp synthetase II does not	642772	
2.7.6.5	additional information	activation of Francisella tularensis RelA by stalled ribosomal complexes formed with ribosomes purified from Escherichia coli MRE600, and significantly weaker activation with ribosomes isolated from Francisella philomiragia	737883	
2.7.6.5	additional information	addition of template, unacylated tRNA and ribosomes to the activity assay stimulates SF 30fold when using optimal conditions, activity of SF increases threefold in the presence of twice salt-washed tight-couple ribosomes and twofold in the presence of reassociated ribosomes compared to the endogenous activity of the enzyme	661712	
2.7.6.5	additional information	GPS I can be activated by incubation with crude mycelial extract, activation is partially inhibited by the inclusion of trypsin inhibitor in reaction mixture	642775	
2.7.6.5	additional information	little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%	642773	
2.7.6.5	additional information	no activation by ribosomes	642775	
2.7.6.5	additional information	ribosome complexes formed with tight binding tRNAVal stimulate enzyme activity at lower concentrations than that required for ribosome complexes formed with the weaker binding tRNAPhe	721638	
2.7.6.5	mRNA	(p)ppGpp synthetase II does not	642772	
2.7.6.5	mRNA	little activity unless activated either by a complex of 70S ribosomes, mRNA and uncharged tRNA or by a solvent like ethanol at approximately 20%	642773	
2.7.6.5	mRNA	synthetic, e.g. poly(U), stimulates, level of stimulation is greater in presence of RNA and poly(U) together than with either RNA alone, no activation by ribosomes	642775	
2.7.6.5	tRNA	uncharged or charged, stimulation, level of stimulation is greater in presence of RNA and poly(U) together than with either RNA alone	642775	
2.7.6.5	Trypsin	incubation with low levels of trypsin activates	642775	
2.7.6.5	unacylated tRNA	in the ribosomal amino-acyl site (A-site)	661712