2.6.1.16 chondroitin sulfate B - 2.6.1.16 Congo red CR, affects the growth, morphology, and activity of glucosamine-6-phosphate synthase in human pathogenic fungus Sporothrix schenckii. Under conditions of yeast development, 0.015 mM CR abolishes conidia germination, but when yeast cells are first obtained in the absence of the dye and then post-incubated in its presence, yeasts rapidly differentiate into mycelial cells. On the other hand, under conditions of mycelium development, 0.150 mM CR do not affect conidia germination, but filamentous cells undergo structural changes characterized by a distorted cell wall contour, the loss of polarity and the formation of red-pigmented, hyphal globose structures. Under these conditions, CR also induces a significant and transient increase in the activity of GlcN-6-P synthase, an essential enzyme in cell wall biogenesis 2.6.1.16 desferrioxamine 0.2 mM 2.6.1.16 desferrioxamine activation of gene expression via iron chelation 2.6.1.16 dithiothreitol 1 mM, activates 1.8fold 2.6.1.16 additional information small acidic compound devoid of SH groups thermolabile at 100°C dialyzable, not precipitable with HClO4 easily separated from proteins in a Sephadex G-25 column 2.6.1.16 additional information requires methionine aminopeptidase activity for proper function 2.6.1.16 Picolinic acid 2 mM 2.6.1.16 Picolinic acid activation of gene expression via iron chelation