2.5.1.6	ATP	tripolyphosphatase activity stimulated by preincubation with ATP and methionine	639068	
2.5.1.6	cycloheximide	cycloheximide inhibition of protein synthesis increases isozyme MAT2 mRNA level in the logarithmic phase only, an indication that the gene is regulated in promastigotes at the posttranscriptional level by protein factors that targets the transcript for degradation	686935	
2.5.1.6	Dimethylsulfoxide	activates alpha and beta isoenzymes from liver	639054	
2.5.1.6	Dimethylsulfoxide	activates isoform from kidney and isoform MAT-III from liver	639043, 639044	
2.5.1.6	Dimethylsulfoxide	activates the beta isozyme from liver 13-15fold	639058	
2.5.1.6	Dimethylsulfoxide	weak activation of the alpha isozyme from liver	639058	
2.5.1.6	dithiothreitol	required for alpha and beta isoenzymes activity, not required for gamma enzyme	639054	
2.5.1.6	E2F1	present continually in the MAT2A promoter during liver regeneration	687118	
2.5.1.6	E2F3	present continually in the MAT2A promoter during liver regeneration	687118	
2.5.1.6	E2F4	present continually in the MAT2A promoter during liver regeneration	687118	
2.5.1.6	Epidermal growth factor	100 ng/ml upregulates MAT2A (but not MAT2beta) expression	686924	
2.5.1.6	forskolin	induction of enzyme in organ cell culture	659509	
2.5.1.6	glycerol	activates rat liver isoenzymes alpha and beta	639054	
2.5.1.6	insulin-like growth factor 1	100 ng/ml upregulates MAT2A (but not MAT2beta) expression	686924	
2.5.1.6	isoproterenol	induction of enzyme in organ cell culture	659509	
2.5.1.6	L-methionine	17% increase is observed at 60 mM L-methionine	686024	
2.5.1.6	L-methionine	17% increase of activity is observed at 60 mM L-methionine	686024	
2.5.1.6	leptin	100 ng/ml upregulates MAT2A (but not MAT2beta) expression	686924	
2.5.1.6	leptin	induces the expression of MAT2A and MAT2beta	687010	
2.5.1.6	methanol	53.26% increased yield of S-adenosyl-L-methionine at 1.0% methanol	687859	
2.5.1.6	methionine	stimulation of activity demonstrated in vivo. Tripolyphosphatase activity stimulated by preincubation with ATP and methionine	639068	
2.5.1.6	additional information	cell methionine and S-adenosylmethionine contents increase in response to hyperoxia in SAE and A549 cells, enzyme activity increases by 2fold within 5 days, S-adenosylmethionine content by 5fold, overview	673793	
2.5.1.6	additional information	fasting for 10-16 h increases expression and activity of isozymes MAT I and MAT III, effects on methionine/S-adenosyl-L-methionine metabolism, overview	675572	
2.5.1.6	additional information	lysine enhances methionine content by modulating the expression of S-adenosylmethionine synthase, overview	676530	
2.5.1.6	additional information	methanol induces enzyme expression and S-adenosyl-L-methionine production, while glycerol does not	673398	
2.5.1.6	additional information	no effect with ADP and methionine or S-adenosylmethionine	639068	
2.5.1.6	additional information	no requirement for reducing agents	639048	
2.5.1.6	additional information	no significant effect in the presence of n-dodecane	687859	
2.5.1.6	additional information	salt stress induces the enzyme, differential effects on betaine and lignin biosynthesis, overview	660154	
2.5.1.6	n-heptane	53.26% increased yield of S-adenosyl-L-methionine at 1.0% n-heptane	687859	
2.5.1.6	norepinephrine	induction of enzyme in organ cell culture	659509	
2.5.1.6	reduced thioredoxin	increases the activity	759436	
2.5.1.6	S-adenosylmethionine	activates the tripolyphosphatase activity of A isoform	639048	
2.5.1.6	S-adenosylmethionine	activation of rat liver MAT-III	639043, 639044	
2.5.1.6	S-adenosylmethionine	below 0.3 mM activates low-MW isoenzyme	639053	
2.5.1.6	S-adenosylmethionine	enhances tripolyphosphatase activity	639056	
2.5.1.6	S-adenosylmethionine	nonessential activator of tripolyphosphatase activity in the range of 0.005-0.100 mM	639078	
2.5.1.6	SH-reagents	liver enzyme: requirement, tumor enzyme: no requirement	639042	
2.5.1.6	sorbitol	53.26% increased yield of S-adenosyl-L-methionine at 1.2% sorbitol	687859	
2.5.1.6	Sp1	binding of Sp1 to the MAT2A promoter is essential for the transcriptional up-regulation of the gene	687118	
2.5.1.6	tripolyphosphates	activation or inhibition, depending on isoenzyme, S-adenosylmethionine and tripolyphosphate concentration	639054	
2.5.1.6	Tumor necrosis factor alpha	induces expression of variant 1 (but not variant 2) MAT2beta	686926