1.14.14.25	cholesterol 3-sulfate	i.e. CH-35	
1.14.14.25	efavirenz	EFV, activates the enzyme pharmacologically as a potential target for Alzheimers disease	
1.14.14.25	lovastatin	induces and activates the enzyme, acts neuroprotectively in hippocampus after kainate injury, overview	
1.14.14.25	additional information	cortical injury increases cholesterol 24S hydroxylase levels in the rat brain, overview	
1.14.14.25	additional information	pharmaceuticals activate CYP46A1 allosterically through binding to the site on the cytosolic protein surface, which is different from the enzyme active site facing the membrane