1.11.2.2 5-aminosalicylic acid converts inactive myeloperoxidase compound II rapidly into active myeloperoxidase 711274 1.11.2.2 ascorbic acid 200% activation at 0.002 mM and pH 5.2 439757 1.11.2.2 ascorbic acid converts inactive myeloperoxidase compound II into active myeloperoxidase 711274 1.11.2.2 betanin low micromolar betanin concentrations enhance the chlorination activity of MPO at pH 7.0, increasing the betanin concentration up to 0.006 mM dramatically increases the chlorination rate of monochlorodimedon 711064 1.11.2.2 chloride in the presence of 100 mM NaCl the catalytic efficiency of MPO increases 3-4fold whatever the sulfide considered, the rate of 4-tolyl methyl sulphide oxidation enhancement is about 8fold at 120 mM NaCl 711125 1.11.2.2 D-penicillamine addition of D-penicillamine significantly enhances the rate of chloroacetonitrile oxidation and cyanide release by the myeloperoxidase/H2O2/Cl- system (17.2% increase at 5 mM) 713543 1.11.2.2 ferrocyanide converts inactive myeloperoxidase compound II into active myeloperoxidase 711274 1.11.2.2 glutathione addition of glutathione significantly enhances the rate of chloroacetonitrile oxidation and cyanide release by the myeloperoxidase/H2O2/Cl- system (24% increase at 5 mM) 713543 1.11.2.2 indicaxanthin at neutral pH and depending on their concentration, indicaxanthin can exhibit a stimulating and inhibitory effect on the chlorination activity of MPO 711064 1.11.2.2 L-cysteine addition of L-cysteine significantly enhances the rate of chloroacetonitrile oxidation and cyanide release by the myeloperoxidase/H2O2/Cl- system (45.4% increase at 5 mM) 713543 1.11.2.2 additional information hypercholesterolemia results in higher tissue MPO activities, the influences of fish oil on MPO activities are not obvious in hypercholesterolemic mice with sepsis 699699 1.11.2.2 myelin oligodendrocyte protein MPO activity increases significantly in the myelin oligodendrocyte protein treated rats (0.05 mg) 700150 1.11.2.2 N-acetyl-L-cysteine addition of N-acetyl-L-cysteine significantly enhances the rate of chloroacetonitrile oxidation and cyanide release by the myeloperoxidase/H2O2/Cl- system (16.3% increase at 5 mM) 713543 1.11.2.2 NaCl maximal activity in the presence of 200 mM NaCl 711881 1.11.2.2 serotonin at low micromolar concentrations (below 0.02 mM), serotonin enhances hypochlorite production by both purified myeloperoxidase and neutrophils 711135