1.1.1.41	ADP	-	286775, 760834, 761502, 762451	
1.1.1.41	ADP	activates. Michaelis-Menten constant for DL-isocitrate is lowered 3.5-fold in the wild-type IDH. The substitution of asparagine for aspartate in alpha-mutant enzyme D181N, beta-subunit mutant enzyme D192N, and gamma-subunit mutant enzyme D190N abolishes this allosteric effect of ADP on Km	685154	
1.1.1.41	ADP	allosteric activation by ADP involving residue betaY126. In the presence of 1 mM ADP, the Km,isocitrate is reduced almost equally in the wild-type, 3.6fold, and the alphaY126E mutant, 4.3fold	712440	
1.1.1.41	ADP	allosteric regulation, determination of mol ADP bound to an enzyme tetramer of wild-type and mutant enzymes at different starting concentrations, overview	656189	
1.1.1.41	ADP	the alpha2betagamma heterotetramer and alphagamma heterodimer can be allosterically activated by ADP	762437	
1.1.1.41	AMP	-	286749, 286772, 654783	
1.1.1.41	AMP	activates ICDH-1	286776	
1.1.1.41	AMP	activation of the enzyme and reduction of enzyme inhibition by mitochondrial mRNA, highly enhanced by presence of isocitrate, complex formation, overview	654652	
1.1.1.41	AMP	allosteric activation	656052	
1.1.1.41	AMP	allosteric activation, binds to subunit IDH1	721433	
1.1.1.41	AMP	allosteric activation, isocitrate binding is essential for binding of AMP to IDH1 subunits	721650	
1.1.1.41	AMP	allosteric activator, binding site at subunit IDH1	656118	
1.1.1.41	AMP	four AMP binding sites located on subunit IDH2	721650	
1.1.1.41	ATP	the enzyme can be activated by low concentrations of ATP. At high concentrations ATP is competitive with NAD+ for binding to the catalytic site	762407	
1.1.1.41	citrate	-	760834, 761502, 762407, 762451	
1.1.1.41	citrate	106.29% activity at 1 mM	761311	
1.1.1.41	citrate	110% activity at 2 mM	760649	
1.1.1.41	citrate	the alpha2betagamma heterotetramer and alphagamma heterodimer can be allosterically activated by citrate	762437	
1.1.1.41	DTT	-	721650	
1.1.1.41	DTT	decreases disulfide content of the enzyme, kinetics of enzyme mutants in presence or absence of DTT, overview	721650	
1.1.1.41	additional information	enzyme is not affected by gamma-aminobutyric acid	654914	
1.1.1.41	additional information	the enzyme is not affected by NADP+, HCO3-, and 2-oxoglutarate	654843	
1.1.1.41	NAD+	-	667647