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Information on Organism Streptomyces avermitilis

"Streptomyces avermitilis" Burg et al. 1979; ATCC 31267; DSM 46492; JCM 5070; NBRC 14893; NCIMB 12804; NRRL 8165; Streptomyces avermectinius; Streptomyces avermectinius Takahashi et al. 2002; Streptomyces avermitilis; Streptomyces avermitilis (ex Burg et al. 1979) Kim and Goodfellow 2002; strain MA-4680;

Word Map for Organism Streptomyces avermitilis

Streptomyces avermitilis
avermectins
coelicolor
griseus
anthelmintic
oligomycin
streptomycetes
pentalenolactone
doramectin
lividans
erythraea
milbemycins
pathway-specific
avermectin-producing
abamectin
filipin
macrocyclic
actinorhodin
high-producing
saccharopolyspora
16-membered
alpha-keto

TaxTree of Organism Streptomyces avermitilis

Condensed Tree View

cellular organisms

can be found in Brenda

BRENDA pathways

(superkingdom)

Terrabacteria group can be found in Brenda

can be found in Brenda

Actinobacteria can be found in Brenda

can be found in Brenda

BRENDA pathways

(phylum)

Actinobacteria can be found in Brenda

can be found in Brenda

BRENDA pathways

(class)

Streptomycetales can be found in Brenda

can be found in Brenda

BRENDA pathways

(order)

Streptomycetaceae can be found in Brenda

can be found in Brenda

BRENDA pathways

(family)

Streptomyces can be found in Brenda

can be found in Brenda

BRENDA pathways

(genus)

Streptomyces avermitilis

can be found in Brenda

BRENDA pathways

(species)

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transferred to EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, EC 1.3.8.8, long-chain acyl-CoA dehydrogenase and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase

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transferred to EC 1.14.15.33

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preliminary BRENDA-supplied EC number

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Biosynthesis of secondary metabolites

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isoprene biosynthesis II (engineered)

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Metabolic pathways

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mevalonate metabolism

mevalonate metabolism

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mevalonate pathway I

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mevalonate pathway II (archaea)

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mevalonate pathway III (archaea)

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Terpenoid backbone biosynthesis

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(S)-lactate fermentation to propanoate, acetate and hydrogen

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alanine metabolism

alanine metabolism

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anaerobic energy metabolism (invertebrates, cytosol)

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C4 and CAM-carbon fixation

C4 and CAM-carbon fixation

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C4 photosynthetic carbon assimilation cycle, NAD-ME type

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Carbon fixation in photosynthetic organisms

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Carbon fixation pathways in prokaryotes

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Citrate cycle (TCA cycle)

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citric acid cycle

citric acid cycle

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Cysteine and methionine metabolism

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formaldehyde assimilation I (serine pathway)

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gluconeogenesis I

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gluconeogenesis III

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Glyoxylate and dicarboxylate metabolism

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glyoxylate cycle

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GLYOXYLATE-BYPASS

incomplete reductive TCA cycle

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malate/L-aspartate shuttle pathway

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MALATE-ASPARTATE-SHUTTLE-PWY

Methane metabolism

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methylaspartate cycle

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Microbial metabolism in diverse environments

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mixed acid fermentation

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FERMENTATION-PWY

partial TCA cycle (obligate autotrophs)

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pyruvate fermentation to propanoate I

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Pyruvate metabolism

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reductive TCA cycle I

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reductive TCA cycle II

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superpathway of glyoxylate cycle and fatty acid degradation

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TCA cycle I (prokaryotic)

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TCA cycle II (plants and fungi)

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TCA cycle III (animals)

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TCA cycle IV (2-oxoglutarate decarboxylase)

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TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)

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glucose degradation (oxidative)

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DHGLUCONATE-PYR-CAT-PWY

Glutathione metabolism

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Pentose phosphate pathway

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isoleucine metabolism

isoleucine metabolism

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L-isoleucine biosynthesis I (from threonine)

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L-isoleucine biosynthesis III

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L-valine biosynthesis

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Pantothenate and CoA biosynthesis

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pyruvate fermentation to isobutanol (engineered)

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valine metabolism

valine metabolism

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Valine, leucine and isoleucine biosynthesis

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Arachidonic acid metabolism

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arachidonic acid metabolism

arachidonic acid metabolism

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Folate biosynthesis

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Metabolism of xenobiotics by cytochrome P450

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cholesterol biosynthesis

cholesterol biosynthesis

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cholesterol biosynthesis (plants)

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cholesterol biosynthesis I

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cholesterol biosynthesis II (via 24,25-dihydrolanosterol)

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phytosterol biosynthesis (plants)

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Steroid biosynthesis

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sterol biosynthesis (methylotrophs)

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zymosterol biosynthesis

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Biosynthesis of various secondary metabolites - part 1

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neopentalenoketolactone and pentalenate biosynthesis

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pentalenolactone biosynthesis

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cholesterol degradation to androstenedione I (cholesterol oxidase)

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Steroid degradation

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Glycolysis / Gluconeogenesis

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photosynthesis

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4-coumarate degradation (aerobic)

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4-coumarate degradation (anaerobic)

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Aminobenzoate degradation

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pinoresinol degradation

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trans-caffeate degradation (aerobic)

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vanillin and vanillate degradation I

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vanillin and vanillate degradation II

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2-oxoisovalerate decarboxylation to isobutanoyl-CoA

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pantothenate biosynthesis

pantothenate biosynthesis

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Propanoate metabolism

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Valine, leucine and isoleucine degradation

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lipid metabolism

lipid metabolism

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crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered)

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ethylmalonyl-CoA pathway

Butanoate metabolism

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(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)

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(5Z)-dodecenoate biosynthesis II

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10-cis-heptadecenoyl-CoA degradation (yeast)

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10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)

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6-gingerol analog biosynthesis (engineered)

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9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)

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alpha-Linolenic acid metabolism

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beta-Alanine metabolism

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Biosynthesis of unsaturated fatty acids

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docosahexaenoate biosynthesis III (6-desaturase, mammals)

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fatty acid beta-oxidation II (plant peroxisome)

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fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)

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fatty acid beta-oxidation VI (mammalian peroxisome)

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fatty acid beta-oxidation VII (yeast peroxisome)

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Fatty acid degradation

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jasmonic acid biosynthesis

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methyl ketone biosynthesis (engineered)

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oleate beta-oxidation (isomerase-dependent, yeast)

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propanoyl-CoA degradation II

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Arginine and proline metabolism

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beta-alanine biosynthesis I

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histamine degradation

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Histidine metabolism

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histidine metabolism

histidine metabolism

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N-methyl-Delta1-pyrrolinium cation biosynthesis

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Tryptophan metabolism

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Oxidative phosphorylation

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ammonia oxidation II (anaerobic)

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denitrification

denitrification

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nitrate reduction I (denitrification)

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DENITRIFICATION-PWY

nitrate reduction VII (denitrification)

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nitrifier denitrification

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nitrite-dependent anaerobic methane oxidation

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Nitrogen metabolism

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ethanol degradation IV

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methanol oxidation to formaldehyde IV

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non-pathway related

non-pathway related

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reactive oxygen species degradation

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superoxide radicals degradation

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baicalein degradation (hydrogen peroxide detoxification)

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betanidin degradation

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justicidin B biosynthesis

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luteolin triglucuronide degradation

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matairesinol biosynthesis

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Phenylpropanoid biosynthesis

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sesamin biosynthesis

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Drug metabolism - other enzymes

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methane metabolism

methane metabolism

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Phenylalanine metabolism

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hydrogen production

hydrogen production

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hydrogen production III

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hydrogen production VI

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hydrogen production VIII

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L-glutamate degradation VII (to butanoate)

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superpathway of fermentation (Chlamydomonas reinhardtii)

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hydrogen oxidation I (aerobic)

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Nitrotoluene degradation

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2-nitrotoluene degradation

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Benzoate degradation

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catechol degradation to 2-hydroxypentadienoate I

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catechol degradation to 2-hydroxypentadienoate II

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Chlorocyclohexane and chlorobenzene degradation

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phenol degradation

phenol degradation

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Styrene degradation

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toluene degradation to 2-hydroxypentadienoate (via 4-methylcatechol)

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TOLUENE-DEG-3-OH-PWY

toluene degradation to 2-hydroxypentadienoate (via toluene-cis-diol)

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TOLUENE-DEG-DIOL-PWY

toluene degradation to 2-hydroxypentadienoate I (via o-cresol)

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TOLUENE-DEG-2-OH-PWY

Xylene degradation

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L-phenylalanine degradation IV (mammalian, via side chain)

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L-tyrosine degradation I

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plastoquinol-9 biosynthesis I

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Tyrosine metabolism

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tyrosine metabolism

tyrosine metabolism

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Ubiquinone and other terpenoid-quinone biosynthesis

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vitamin E biosynthesis (tocopherols)

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flavonoid biosynthesis

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Flavonoid biosynthesis

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flavonoid biosynthesis (in equisetum)

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leucodelphinidin biosynthesis

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leucopelargonidin and leucocyanidin biosynthesis

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pinobanksin biosynthesis

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1,5-anhydrofructose degradation

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acetone degradation I (to methylglyoxal)

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acetone degradation III (to propane-1,2-diol)

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Amaryllidacea alkaloids biosynthesis

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bupropion degradation

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Caffeine metabolism

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Drug metabolism - cytochrome P450

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Linoleic acid metabolism

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melatonin degradation I

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nicotine degradation IV

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nicotine degradation V

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Retinol metabolism

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Steroid hormone biosynthesis

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vanillin biosynthesis I

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bacterial bioluminescence

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(+)-camphor degradation

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(-)-camphor degradation

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Sesquiterpenoid and triterpenoid biosynthesis

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Biosynthesis of 12-, 14- and 16-membered macrolides

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methymycin, neomethymycin and novamethymycin biosynthesis

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narbomycin, pikromycin and novapikromycin biosynthesis

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Betalain biosynthesis

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firefly bioluminescence

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Isoquinoline alkaloid biosynthesis

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L-dopa and L-dopachrome biosynthesis

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pheomelanin biosynthesis

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capsaicin biosynthesis

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chlorogenic acid biosynthesis I

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coumarins biosynthesis (engineered)

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phenylpropanoid biosynthesis

phenylpropanoids methylation (ice plant)

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scopoletin biosynthesis

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Stilbenoid, diarylheptanoid and gingerol biosynthesis

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suberin monomers biosynthesis

Isoflavonoid biosynthesis

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isoflavonoid biosynthesis I

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isoflavonoid biosynthesis II

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sakuranetin biosynthesis

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2-methylisoborneol biosynthesis

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Arginine biosynthesis

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L-arginine biosynthesis I (via L-ornithine)

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L-arginine biosynthesis II (acetyl cycle)

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L-arginine biosynthesis IV (archaebacteria)

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L-citrulline biosynthesis

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L-citrulline degradation

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CITRULLINE-DEG-PWY

L-proline biosynthesis II (from arginine)

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urea cycle

acetoin degradation

acetoin degradation

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C5-Branched dibasic acid metabolism

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L-isoleucine biosynthesis II

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L-isoleucine biosynthesis IV

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pyruvate fermentation to (R)-acetoin I

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pyruvate fermentation to (R)-acetoin II

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pyruvate fermentation to (S)-acetoin

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Cutin, suberine and wax biosynthesis

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diacylglycerol and triacylglycerol biosynthesis

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Glycerolipid metabolism

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bryostatin biosynthesis

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Fatty acid biosynthesis

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fatty acid biosynthesis initiation (bacteria and plants)

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fatty acid biosynthesis initiation (mitochondria)

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fatty acid biosynthesis initiation (plant mitochondria)

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mupirocin biosynthesis

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pederin biosynthesis

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aromatic polyketides biosynthesis

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flavonoid di-C-glucosylation

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naringenin biosynthesis (engineered)

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phloridzin biosynthesis

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xanthohumol biosynthesis

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cuticular wax biosynthesis

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long chain fatty acid ester synthesis (engineered)

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wax esters biosynthesis I

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wax esters biosynthesis II

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fatty acid biosynthesis initiation (animals and fungi, cytoplasm)

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palmitate biosynthesis (animals and fungi, cytoplasm)

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erythromycin D biosynthesis

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6-methylpretetramide biosynthesis

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Biosynthesis of type II polyketide backbone

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Tetracycline biosynthesis

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lipid A biosynthesis

lipid A biosynthesis

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lipid A-core biosynthesis (E. coli K-12)

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LIPA-CORESYN-PWY

Monoterpenoid biosynthesis

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adenine and adenosine salvage I

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adenine and adenosine salvage III

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adenine and adenosine salvage V

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adenosine nucleotides degradation II

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SALVADEHYPOX-PWY

arsenate detoxification I (mammalian)

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fluoroacetate and fluorothreonine biosynthesis

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guanine and guanosine salvage

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guanosine nucleotides degradation III

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inosine 5'-phosphate degradation

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Nicotinate and nicotinamide metabolism

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nucleoside and nucleotide degradation (archaea)

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purine deoxyribonucleosides degradation I

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purine deoxyribonucleosides degradation II

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Purine metabolism

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purine metabolism

purine metabolism

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purine ribonucleosides degradation

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Pyrimidine metabolism

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salinosporamide A biosynthesis

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xanthine and xanthosine salvage

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SALVPURINE2-PWY

2'-deoxymugineic acid phytosiderophore biosynthesis

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ethylene biosynthesis I (plants)

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L-methionine degradation I (to L-homocysteine)

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METHIONINE-DEG1-PWY

methionine metabolism

methionine metabolism

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S-adenosyl-L-methionine biosynthesis

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S-adenosyl-L-methionine cycle II

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4-hydroxy-2-nonenal detoxification

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camalexin biosynthesis

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gliotoxin biosynthesis

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glutathione metabolism

glutathione metabolism

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glutathione-mediated detoxification I

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glutathione-mediated detoxification II

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indole glucosinolate activation (intact plant cell)

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pentachlorophenol degradation

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cysteine metabolism

cysteine metabolism

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L-cysteine biosynthesis I

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seleno-amino acid biosynthesis (plants)

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Sulfur metabolism

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L-lysine biosynthesis I

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DAPLYSINESYN-PWY

Lysine biosynthesis

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lysine metabolism

lysine metabolism

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L-phenylalanine biosynthesis II

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L-tyrosine biosynthesis II

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L-tyrosine biosynthesis III

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phenylalanine metabolism

phenylalanine metabolism

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Phenylalanine, tyrosine and tryptophan biosynthesis

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coenzyme A metabolism

coenzyme A metabolism

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phosphopantothenate biosynthesis I

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phosphopantothenate biosynthesis II

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superpathway of coenzyme A biosynthesis III (mammals)

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acyl carrier protein activation

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acyl carrier protein metabolism

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enterobactin biosynthesis

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petrobactin biosynthesis

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Thiamine metabolism

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vitamin B1 metabolism

vitamin B1 metabolism

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[2Fe-2S] iron-sulfur cluster biosynthesis

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oxalate degradation II

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methyl indole-3-acetate interconversion

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methylsalicylate degradation

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retinol biosynthesis

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superpathway of methylsalicylate metabolism

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Bisphenol degradation

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triacylglycerol degradation

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degradation of sugar alcohols

degradation of sugar alcohols

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Glycerophospholipid metabolism

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phospholipid remodeling (phosphatidylethanolamine, yeast)

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sterol:steryl ester interconversion (yeast)

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chlorophyll a degradation I

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chlorophyll a degradation II

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chlorophyll a degradation III

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chlorophyll metabolism

chlorophyll metabolism

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Porphyrin and chlorophyll metabolism

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anandamide biosynthesis I

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phosphatidylcholine acyl editing

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phospholipases

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cellulose and hemicellulose degradation (cellulolosome)

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phosphatidylcholine resynthesis via glycerophosphocholine

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tRNA processing

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(1,4)-beta-D-xylan degradation

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d-xylose degradation

d-xylose degradation

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Amino sugar and nucleotide sugar metabolism

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chitin degradation I (archaea)

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chitin degradation II (Vibrio)

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chitin degradation III (Serratia)

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Galactose metabolism

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Glycosphingolipid biosynthesis - globo and isoglobo series

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melibiose degradation

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metabolism of disaccharids

metabolism of disaccharids

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Sphingolipid metabolism

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stachyose degradation

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Glycosaminoglycan degradation

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Glycosphingolipid biosynthesis - ganglio series

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lactose degradation II

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LACTOSEUTIL-PWY

Other glycan degradation

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xyloglucan degradation II (exoglucanase)

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beta-D-glucuronide and D-glucuronate degradation

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degradation of sugar acids

degradation of sugar acids

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Flavone and flavonol biosynthesis

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Pentose and glucuronate interconversions

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anhydromuropeptides recycling I

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anhydromuropeptides recycling II

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Various types of N-glycan biosynthesis

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degradation of pentoses

degradation of pentoses

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fructan degradation

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Fructose and mannose metabolism

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Alanine, aspartate and glutamate metabolism

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aspartate and asparagine metabolism

aspartate and asparagine metabolism

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Cyanoamino acid metabolism

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L-asparagine degradation I

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ASPARAGINE-DEG1-PWY

L-asparagine degradation III (mammalian)

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ASPARAGINE-DEG1-PWY-1

superpathway of L-aspartate and L-asparagine biosynthesis

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acrylonitrile degradation I

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arginine metabolism

arginine metabolism

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degradation of aromatic, nitrogen containing compounds

degradation of aromatic, nitrogen containing compounds

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IAA biosynthesis

IAA biosynthesis

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indole-3-acetate biosynthesis II

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indole-3-acetate biosynthesis III (bacteria)

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indole-3-acetate biosynthesis IV (bacteria)

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L-arginine degradation X (arginine monooxygenase pathway)

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Penicillin and cephalosporin biosynthesis

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1,4-dihydroxy-6-naphthoate biosynthesis

1,4-dihydroxy-6-naphthoate biosynthesis

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1,4-dihydroxy-6-naphthoate biosynthesis I

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glycine biosynthesis IV

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Glycine, serine and threonine metabolism

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L-threonine degradation IV

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geosmin biosynthesis

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gossypol biosynthesis

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lacinilene C biosynthesis

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albaflavenone biosynthesis

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farnesene biosynthesis

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L-arginine degradation VII (arginase 3 pathway)

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L-ornithine degradation I (L-proline biosynthesis)

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ORN-AMINOPENTANOATE-CAT-PWY

L-threonine degradation V

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serine metabolism

serine metabolism

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threonine metabolism

threonine metabolism

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dimethyl sulfide biosynthesis from methionine

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Selenocompound metabolism

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dTDP-4-O-demethyl-beta-L-noviose biosynthesis

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dTDP-L-daunosamine biosynthesis

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dTDP-L-rhamnose biosynthesis

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DTDPRHAMSYN-PWY

dTDPLrhamnose biosynthesis

dTDPLrhamnose biosynthesis

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Polyketide sugar unit biosynthesis

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Streptomycin biosynthesis

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D-xylose degradation I

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1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)

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1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)

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di-myo-inositol phosphate biosynthesis

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Inositol phosphate metabolism

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mycothiol biosynthesis

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myo-inositol biosynthesis

phosphatidylinositol biosynthesis I (bacteria)

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echinatin biosynthesis

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Aminoacyl-tRNA biosynthesis

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tRNA charging

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TRNA-CHARGING-PWY

tryptophan metabolism

tryptophan metabolism

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L-selenocysteine biosynthesis I (bacteria)

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L-selenocysteine biosynthesis II (archaea and eukaryotes)

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selenocysteine biosynthesis

selenocysteine biosynthesis

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acetate conversion to acetyl-CoA

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acetate fermentation

acetate fermentation

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adlupulone and adhumulone biosynthesis

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chitin degradation to ethanol

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-

cis-genanyl-CoA degradation

-

-

colupulone and cohumulone biosynthesis

-

-

ethanol degradation II

-

-

ethanol degradation III

-

-

L-isoleucine biosynthesis V

-

-

lupulone and humulone biosynthesis

-

-

propanol degradation

propanol degradation

-

-

Atrazine degradation

-

-

urea degradation I

-

-

biotin biosynthesis

biotin biosynthesis

-

-

Biotin metabolism

-

-

biotin-carboxyl carrier protein assembly

-

-

L-asparagine biosynthesis I

-

-

ASPARAGINE-BIOSYNTHESIS

Aflatoxin biosynthesis

-

-

CO2 fixation in Crenarchaeota

CO2 fixation in Crenarchaeota

-

-

jadomycin biosynthesis

-

-

3-hydroxypropanoate cycle

-

-

3-hydroxypropanoate/4-hydroxybutanate cycle

-

-

anaerobic energy metabolism (invertebrates, mitochondrial)

-

-

mycolate biosynthesis

-

-

propanoyl CoA degradation I

-

-

propionate fermentation

propionate fermentation

-

-

oleandomycin activation/inactivation

-

-

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Streptomyces avermitilis

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enrichment culture

Streptomyces avermitilis

oxalate enrichment culture

Manually annotated by BRENDA team

Streptomyces avermitilis

-

Manually annotated by BRENDA team

Streptomyces avermitilis

soil samples are collected below the Ca-oxalate producing trees Milicia excelsa and Afzelia africana and in a similar soil distant from trees

Manually annotated by BRENDA team

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show

Streptomyces avermitilis

-

-

Manually annotated by BRENDA team

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NCBI: Taxonomy, PubMed, Genome

SILVA: 16S/18S rRNA, 23S/28S rRNA