Any feedback?
BRENDA home
Organism related
TaxTree of Organism Saccharomyces cerevisiae BY4741
Condensed Tree View
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
EC NUMBER 
COMMENTARY 
-
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)
-
-
PWY-7728
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)
-
-
PWY-7726
(9Z)-tricosene biosynthesis
-
-
PWY-7035
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)
-
-
PWY-7216
(R,R)-butanediol biosynthesis
-
-
PWY-5951
(R,R)-butanediol degradation
-
-
PWY3O-246
1,3-propanediol biosynthesis (engineered)
-
-
PWY-7385
1,5-anhydrofructose degradation
-
-
PWY-6992
1-butanol autotrophic biosynthesis (engineered)
-
-
PWY-6886
1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)
-
-
PWY-6361
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
-
-
PWY-6362
2'-deoxymugineic acid phytosiderophore biosynthesis
-
-
PWY-5912
2-deoxy-D-ribose degradation II
-
-
PWY-8058
2-methylpropene degradation
-
-
PWY-7778
24-epi-campesterol, fucosterol, and clionasterol biosynthesis (diatoms)
-
-
PWY-8238
3-hydroxypropanoate/4-hydroxybutanate cycle
-
-
PWY-5789
3-methylbutanol biosynthesis (engineered)
-
-
PWY-6871
4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis II
-
-
PWY-7282
4-hydroxy-2-nonenal detoxification
-
-
PWY-7112
4-oxopentanoate degradation
-
-
PWY-7948
Ac/N-end rule pathway
-
-
PWY-7800
acetaldehyde biosynthesis II
-
-
PWY-6330
acetoacetate degradation (to acetyl CoA)
-
-
ACETOACETATE-DEG-PWY
acetone degradation I (to methylglyoxal)
-
-
PWY-5451
acetone degradation III (to propane-1,2-diol)
-
-
PWY-7466
acetyl-CoA fermentation to butanoate
-
-
PWY-5676
all-trans-farnesol biosynthesis
-
-
PWY-6859
Amaryllidacea alkaloids biosynthesis
-
-
PWY-7826
anaerobic energy metabolism (invertebrates, mitochondrial)
-
-
PWY-7384
anandamide biosynthesis I
-
-
PWY-8051
arachidonate biosynthesis I (6-desaturase, lower eukaryotes)
-
-
PWY-5353
arachidonate biosynthesis III (6-desaturase, mammals)
-
-
PWY-7592
arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)
-
-
PWY-7601
arachidonate biosynthesis V (8-detaturase, mammals)
-
-
PWY-7725
Arg/N-end rule pathway (eukaryotic)
-
-
PWY-7799
arsenate detoxification I
-
-
PWY-8264
arsenate detoxification III
-
-
PWY-8263
arsenic detoxification (plants)
-
-
PWY-8259
arsenic detoxification (yeast)
-
-
PWY-4621
ATP biosynthesis
-
-
PWY-7980
Bifidobacterium shunt
-
-
P124-PWY
bisabolene biosynthesis (engineered)
-
-
PWY-7102
bupropion degradation
-
-
PWY66-241
butanol and isobutanol biosynthesis (engineered)
-
-
PWY-7396
Calvin-Benson-Bassham cycle
-
-
CALVIN-PWY
camalexin biosynthesis
-
-
CAMALEXIN-SYN
cellulose degradation II (fungi)
-
-
PWY-6788
cholesterol biosynthesis (algae, late side-chain reductase)
-
-
PWY-8191
cholesterol biosynthesis (diatoms)
-
-
PWY-8239
cholesterol biosynthesis (plants, early side-chain reductase)
-
-
PWY18C3-1
cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
-
-
PWY66-3
coenzyme B biosynthesis
-
-
P241-PWY
crotonate fermentation (to acetate and cyclohexane carboxylate)
-
-
PWY-7401
cytosolic NADPH production (yeast)
-
-
PWY-7268
D-arabinose degradation V
-
-
PWY-8334
D-galactose degradation IV
-
-
PWY-6693
D-myo-inositol (1,3,4)-trisphosphate biosynthesis
-
-
PWY-6364
daidzein conjugates interconversion
-
-
PWY-2343
daidzin and daidzein degradation
-
-
PWY-6996
detoxification of reactive carbonyls in chloroplasts
-
-
PWY-6786
diacylglycerol and triacylglycerol biosynthesis
-
-
TRIGLSYN-PWY
diphthamide biosynthesis I (archaea)
-
-
PWY-6482
diphthamide biosynthesis II (eukaryotes)
-
-
PWY-7546
docosahexaenoate biosynthesis I (lower eukaryotes)
-
-
PWY-7053
docosahexaenoate biosynthesis III (6-desaturase, mammals)
-
-
PWY-7606
docosahexaenoate biosynthesis IV (4-desaturase, mammals)
-
-
PWY-7727
dTMP de novo biosynthesis (mitochondrial)
-
-
PWY66-385
Entner-Doudoroff pathway I
-
-
PWY-8004
epoxysqualene biosynthesis
-
-
PWY-5670
ergosterol biosynthesis II
-
-
PWY-7154
ethene biosynthesis I (plants)
-
-
ETHYL-PWY
ethene biosynthesis III (microbes)
-
-
PWY-6854
ethylmalonyl-CoA pathway
-
-
PWY-5741
FeMo cofactor biosynthesis
-
-
PWY-7710
folate polyglutamylation
folate transformations I
-
-
PWY-2201
folate transformations II (plants)
-
-
PWY-3841
folate transformations III (E. coli)
-
-
1CMET2-PWY
formaldehyde assimilation I (serine pathway)
-
-
PWY-1622
formaldehyde assimilation III (dihydroxyacetone cycle)
-
-
P185-PWY
formaldehyde oxidation II (glutathione-dependent)
-
-
PWY-1801
formononetin conjugates interconversion
-
-
PWY-2904
genistein conjugates interconversion
-
-
PWY-2345
gliotoxin biosynthesis
-
-
PWY-7533
gluconeogenesis I
-
-
GLUCONEO-PWY
gluconeogenesis III
-
-
PWY66-399
glutaryl-CoA degradation
-
-
PWY-5177
glutathione-mediated detoxification I
-
-
PWY-4061
glutathione-mediated detoxification II
-
-
PWY-6842
glycerol degradation to butanol
-
-
PWY-7003
glycerol-3-phosphate shuttle
-
-
PWY-6118
glycine betaine degradation I
-
-
PWY-3661
glycine betaine degradation II (mammalian)
-
-
PWY-3661-1
glycine betaine degradation III
-
-
PWY-8325
glycine biosynthesis I
-
-
GLYSYN-PWY
glycogen degradation II
-
-
PWY-5941
glycolysis I (from glucose 6-phosphate)
-
-
GLYCOLYSIS
glycolysis II (from fructose 6-phosphate)
-
-
PWY-5484
glycolysis III (from glucose)
-
-
ANAGLYCOLYSIS-PWY
glycolysis IV
-
-
PWY-1042
heterolactic fermentation
-
-
P122-PWY
hydroxylated fatty acid biosynthesis (plants)
-
-
PWY-6433
icosapentaenoate biosynthesis I (lower eukaryotes)
-
-
PWY-6958
icosapentaenoate biosynthesis II (6-desaturase, mammals)
-
-
PWY-7049
icosapentaenoate biosynthesis III (8-desaturase, mammals)
-
-
PWY-7724
icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)
-
-
PWY-7602
indole glucosinolate activation (intact plant cell)
-
-
PWYQT-4477
isoprene biosynthesis II (engineered)
-
-
PWY-7391
isopropanol biosynthesis (engineered)
-
-
PWY-6876
juniperonate biosynthesis
-
-
PWY-7619
ketogenesis
-
-
PWY66-367
ketolysis
-
-
PWY66-368
L-arabinose degradation II
-
-
PWY-5515
L-asparagine degradation I
-
-
ASPARAGINE-DEG1-PWY
L-asparagine degradation III (mammalian)
-
-
ASPARAGINE-DEG1-PWY-1
L-glutamate biosynthesis III
-
-
GLUTSYNIII-PWY
L-glutamate degradation V (via hydroxyglutarate)
-
-
P162-PWY
L-leucine biosynthesis
-
-
LEUSYN-PWY
L-lysine biosynthesis IV
-
-
LYSINE-AMINOAD-PWY
L-lysine biosynthesis V
-
-
PWY-3081
L-lysine degradation V
-
-
PWY-5283
L-lysine fermentation to acetate and butanoate
-
-
P163-PWY
L-methionine degradation I (to L-homocysteine)
-
-
METHIONINE-DEG1-PWY
L-methionine degradation III
-
-
PWY-5082
long chain fatty acid ester synthesis (engineered)
-
-
PWY-6873
manganese oxidation I
-
-
PWY-6591
melatonin degradation I
-
-
PWY-6398
methyl indole-3-acetate interconversion
-
-
PWY-6303
methyl phomopsenoate biosynthesis
-
-
PWY-7721
methyl tert-butyl ether degradation
-
-
PWY-7779
methylglyoxal degradation III
-
-
PWY-5453
methylsalicylate degradation
-
-
PWY18C3-24
mevalonate pathway I (eukaryotes and bacteria)
-
-
PWY-922
mevalonate pathway II (haloarchaea)
-
-
PWY-6174
mevalonate pathway III (Thermoplasma)
-
-
PWY-7524
mevalonate pathway IV (archaea)
-
-
PWY-8125
mitochondrial NADPH production (yeast)
-
-
PWY-7269
monoacylglycerol metabolism (yeast)
-
-
PWY-7420
NAD salvage pathway V (PNC V cycle)
-
-
PWY3O-4107
NAD(P)/NADPH interconversion
-
-
PWY-5083
nicotine degradation IV
-
-
PWY66-201
nicotine degradation V
-
-
PWY66-221
oleandomycin activation/inactivation
-
-
PWY-6972
oleate beta-oxidation
-
-
PWY0-1337
oxalate degradation VI
-
-
PWY-7985
pentachlorophenol degradation
-
-
PCPDEG-PWY
phosphatidate biosynthesis (yeast)
-
-
PWY-7411
phosphatidylcholine acyl editing
-
-
PWY-6803
phosphatidylserine and phosphatidylethanolamine biosynthesis I
-
-
PWY-5669
phospholipases
-
-
LIPASYN-PWY
photorespiration I
-
-
PWY-181
photorespiration II
-
-
PWY-8362
photorespiration III
-
-
PWY-8363
photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
-
-
PWY-7218
phytosterol biosynthesis (plants)
-
-
PWY-2541
polyhydroxybutanoate biosynthesis
-
-
PWY1-3
protein N-glycosylation processing phase (plants and animals)
-
-
PWY-7919
protein S-nitrosylation and denitrosylation
-
-
PWY-7798
protein ubiquitination
-
-
PWY-7511
purine nucleobases degradation II (anaerobic)
-
-
PWY-5497
putrescine biosynthesis III
-
-
PWY-46
pyridoxal 5'-phosphate biosynthesis I
-
-
PYRIDOXSYN-PWY
pyridoxal 5'-phosphate salvage I
-
-
PLPSAL-PWY
pyridoxal 5'-phosphate salvage II (plants)
-
-
PWY-7204
pyruvate decarboxylation to acetyl CoA I
-
-
PYRUVDEHYD-PWY
pyruvate fermentation to acetate II
-
-
PWY-5482
pyruvate fermentation to acetate V
-
-
PWY-5537
pyruvate fermentation to acetate VIII
-
-
PWY-5768
pyruvate fermentation to acetoin III
-
-
PWY3O-440
pyruvate fermentation to acetone
-
-
PWY-6588
pyruvate fermentation to butanoate
-
-
CENTFERM-PWY
pyruvate fermentation to butanol I
-
-
PWY-6583
pyruvate fermentation to butanol II (engineered)
-
-
PWY-6883
pyruvate fermentation to ethanol II
-
-
PWY-5486
pyruvate fermentation to hexanol (engineered)
-
-
PWY-6863
quercetin glucoside degradation (Allium)
-
-
PWY-7133
reactive oxygen species degradation
-
-
DETOX1-PWY-1
retinol biosynthesis
-
-
PWY-6857
rutin degradation (plants)
-
-
PWY-7134
S-adenosyl-L-methionine biosynthesis
-
-
SAM-PWY
S-adenosyl-L-methionine salvage I
-
-
PWY-6151
S-adenosyl-L-methionine salvage II
-
-
PWY-5041
sciadonate biosynthesis
-
-
PWY-6598
sphingolipid biosynthesis (yeast)
-
-
SPHINGOLIPID-SYN-PWY
stellatic acid biosynthesis
-
-
PWY-7736
sucrose biosynthesis I (from photosynthesis)
-
-
SUCSYN-PWY
superoxide radicals degradation
-
-
DETOX1-PWY
superpathway of glucose and xylose degradation
-
-
PWY-6901
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass
-
-
GLYCOLYSIS-TCA-GLYOX-BYPASS
superpathway of L-aspartate and L-asparagine biosynthesis
-
-
ASPASN-PWY
superpathway of methylsalicylate metabolism
-
-
PWY18C3-25
superpathway of ornithine degradation
-
-
ORNDEG-PWY
trans, trans-farnesyl diphosphate biosynthesis
-
-
PWY-5123
triacylglycerol degradation
-
-
LIPAS-PWY
tRNA methylation (yeast)
-
-
PWY-6829
ultra-long-chain fatty acid biosynthesis
-
-
PWY-8041
UMP biosynthesis I
-
-
PWY-5686
UMP biosynthesis II
-
-
PWY-7790
UMP biosynthesis III
-
-
PWY-7791
valproate beta-oxidation
-
-
PWY-8182
vanillin biosynthesis I
-
-
PWY-5665
very long chain fatty acid biosynthesis I
-
-
PWY-5080
very long chain fatty acid biosynthesis II
-
-
PWY-7036
zymosterol biosynthesis
-
-
PWY-6074
folate polyglutamylation
-
-
PWY-2161
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
663233, 679852, 687812, 694438, 698007, 698782, 701727, 703640, 707657, 710844, 711582, 711976, 715933, 716398, 718781, 720500, 722693, 723176, 725070, 727269, 727559, 727560, 727929, 728542, 730046, 734323, 734628, 735147, 735538, 736032, 736542, 737106, 737227, 737299, 739694, 740862, 741300, 743584, 745307, 746123, 746726, 747803, 747805, 749279, 749810, 750706, 751295, 751747, 752840, 753586, 753744, 754084, 754091, 754727, 755447, 756082, 756534, 757172, 759021, 759725, 760048
-
-
-
UniProt
isozyme PDC1; pyruvate decarboxylase isozyme 1
SwissProt
isozyme PDC5; pyruvate decarboxylase isozyme 2, PDC5
UniProt
isozyme PDC6; pyruvate decarboxylase isozyme 3, PDC6
UniProt
NuA4 is a 13-subunit KAT complex containing the essential catalytic domain Esa1
Uniprot
two NADP+-dependent glutamate dehydrogenases encoded by GDH1 and GDH3
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
additional information
-
growth profile and ethanol production in isozyme knockout strains, overview
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
additional information
-
aconitase in yeast is a single translation product, which is dual targeted and distributed between the mitochondria and the cytosol by a unique mechanism involving reverse translocation, dual localization, detailed overview
-
aconitase in yeast is a single translation product, which is dual targeted and distributed between the mitochondria and the cytosol by a unique mechanism involving reverse translocation, dual localization, detailed overview
-
the enzyme requires integration into the inner mitochondrial membrane for full enzymatic activity
-
in the absence of cadmium, Pca1 is targeted for degradation before reaching the plasma membrane
-
Pca1 contains a cytosolic cysteine-rich N-terminal extension of nearly 400 residue
-
upon phosphate starvation, these low-affinity phosphate transporters, e.g. Pho87 and Pho90, are endocytosed and targeted to the vacuole. For Pho87, this process strictly depends on SPL2, another Pho4-dependent gene that encodes a protein known to interact with the N-terminal SPX domain of the transporter. In contrast, the vacuolar targeting of Pho90 upon phosphate starvation is independent of both Pho4 and Spl2, although it still requires its SPX domain. Both Pho87 and Pho90 are also targeted to the vacuole upon carbon-source starvation or upon treatment with rapamycin, which mimics nitrogen starvation, responses are independent of PHO pathway signalling requiring only the transporter N-terminal SPX domain. Spl2 mediates phosphate-starvation-induced vacuolar targeting of Pho87, but not of Pho90
additional information
-
in yeast, several plasma membrane nutrient transporters are inactivated and targeted to the vacuole in response to changes in the availability of nutrients
-
additional information
-
Pca1 contains a cytosolic cysteine-rich N-terminal extension of nearly 400 residues
-
additional information
-
subcellular localization study, overview. All mutant aconitase protein molecules are partially imported into mitochondria, then the N-terminal mitochondrial targeting sequence is cleaved off by the mitochondrial processing peptidase. After the cleavage, a subpopulation of the protein molecules moves back into the cytosol by reverse translocation. The aconitase C-terminal domain confers dual targeting
-
LINKS TO OTHER DATABASES (specific for Saccharomyces cerevisiae BY4741)
SILVA: 16S/18S rRNA, 23S/28S rRNA
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
