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TaxTree of Organism Metallosphaera sedula DSM 5348
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EC NUMBER 
COMMENTARY 
-
preliminary BRENDA-supplied EC number
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)
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PWY-7726
(8E,10E)-dodeca-8,10-dienol biosynthesis
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PWY-7654
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)
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PWY-7216
(S)-lactate fermentation to propanoate, acetate and hydrogen
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PWY-8086
2-deoxy-D-ribose degradation II
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PWY-8058
2-methyl-branched fatty acid beta-oxidation
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PWY-8181
2-methylpropene degradation
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PWY-7778
3-hydroxypropanoate cycle
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PWY-5743
3-hydroxypropanoate/4-hydroxybutanate cycle
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PWY-5789
3-phenylpropanoate degradation
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P281-PWY
4-aminobutanoate degradation V
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PWY-5022
4-hydroxybenzoate biosynthesis III (plants)
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PWY-6435
4-oxopentanoate degradation
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PWY-7948
acetoacetate degradation (to acetyl CoA)
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ACETOACETATE-DEG-PWY
acetyl-CoA fermentation to butanoate
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PWY-5676
acrylate degradation II
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PWY-8180
adipate biosynthesis
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PWY-8347
adipate degradation
anaerobic energy metabolism (invertebrates, mitochondrial)
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PWY-7384
androstenedione degradation I (aerobic)
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PWY-6944
androstenedione degradation II (anaerobic)
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PWY-8152
benzoate biosynthesis I (CoA-dependent, beta-oxidative)
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PWY-6443
benzoate biosynthesis III (CoA-dependent, non-beta-oxidative)
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PWY-6446
benzoyl-CoA biosynthesis
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PWY-6458
benzoyl-CoA degradation I (aerobic)
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PWY-1361
beta-alanine degradation III
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PWY-8120
cholesterol degradation to androstenedione I (cholesterol oxidase)
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PWY-6945
cholesterol degradation to androstenedione II (cholesterol dehydrogenase)
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PWY-6946
conversion of succinate to propanoate
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PWY0-43
crotonate fermentation (to acetate and cyclohexane carboxylate)
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PWY-7401
crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered)
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PWY-7854
docosahexaenoate biosynthesis III (6-desaturase, mammals)
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PWY-7606
ethene biosynthesis V (engineered)
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PWY-7124
ethylmalonyl-CoA pathway
fatty acid beta-oxidation I (generic)
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FAO-PWY
fatty acid beta-oxidation II (plant peroxisome)
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PWY-5136
fatty acid beta-oxidation IV (unsaturated, even number)
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PWY-5138
fatty acid beta-oxidation VI (mammalian peroxisome)
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PWY66-391
fatty acid salvage
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PWY-7094
gallate degradation III (anaerobic)
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P3-PWY
glutaryl-CoA degradation
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PWY-5177
glyoxylate assimilation
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PWY-5744
glyoxylate cycle
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GLYOXYLATE-BYPASS
isoprene biosynthesis II (engineered)
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PWY-7391
isopropanol biosynthesis (engineered)
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PWY-6876
ketogenesis
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PWY66-367
ketolysis
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PWY66-368
L-glutamate degradation V (via hydroxyglutarate)
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P162-PWY
L-isoleucine degradation I
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ILEUDEG-PWY
L-lysine fermentation to acetate and butanoate
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P163-PWY
L-valine degradation I
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VALDEG-PWY
methyl ketone biosynthesis (engineered)
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PWY-7007
methyl tert-butyl ether degradation
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PWY-7779
methylaspartate cycle
mevalonate pathway I (eukaryotes and bacteria)
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PWY-922
mevalonate pathway II (haloarchaea)
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PWY-6174
mevalonate pathway III (Thermoplasma)
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PWY-7524
mevalonate pathway IV (archaea)
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PWY-8125
mixed acid fermentation
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FERMENTATION-PWY
nitrogen remobilization from senescing leaves
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PWY-6549
oleate beta-oxidation
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PWY0-1337
partial TCA cycle (obligate autotrophs)
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PWY-5913
phenylacetate degradation I (aerobic)
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PWY0-321
platensimycin biosynthesis
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PWY-8179
polyhydroxybutanoate biosynthesis
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PWY1-3
polyphosphate metabolism
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PWY-8138
propanoate fermentation to 2-methylbutanoate
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PWY-5109
propanoyl CoA degradation I
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PROPIONMET-PWY
pyruvate fermentation to acetone
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PWY-6588
pyruvate fermentation to butanoate
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CENTFERM-PWY
pyruvate fermentation to butanol I
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PWY-6583
pyruvate fermentation to butanol II (engineered)
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PWY-6883
pyruvate fermentation to hexanol (engineered)
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PWY-6863
pyruvate fermentation to propanoate I
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P108-PWY
Spodoptera littoralis pheromone biosynthesis
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PWY-7656
succinate fermentation to butanoate
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PWY-5677
TCA cycle I (prokaryotic)
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TCA
TCA cycle II (plants and fungi)
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PWY-5690
TCA cycle III (animals)
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PWY66-398
TCA cycle IV (2-oxoglutarate decarboxylase)
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P105-PWY
TCA cycle V (2-oxoglutarate synthase)
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PWY-6969
TCA cycle VI (Helicobacter)
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REDCITCYC
TCA cycle VII (acetate-producers)
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PWY-7254
uracil degradation III
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PWY0-1471
valproate beta-oxidation
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PWY-8182
adipate degradation
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PWY-8354
ethylmalonyl-CoA pathway
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PWY-5741
methylaspartate cycle
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PWY-6728
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
A4YEG1: catalytic subunit of methylmalonyl-CoA mutase, A4YIE3: coenzyme B12-binding subunit of methylmalonyl-CoA mutase
A4YEG1, A4YIE3
UniProt
accession number for wild-type enzyme, which shows no activity with 4-hydroxybutanoate, mutant enzyme W424G shows activity
UniProt
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
additional information
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bifunctional crotonyl-CoA hydratase/(S)-3-hydroxybutanoyl-CoA dehydrogenase
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low activity in heterotrophically-grown cell
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no activity in heterotrophically-grown cell
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bifunctional crotonyl-CoA hydratase/(S)-3-hydroxybutanoyl-CoA dehydrogenase
additional information
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transcriptomic analyses of Metallosphaera sedula grown under autotrophic versus heterotrophic conditions, overview. MCE expression is significantly upregulated under autotrophic compared to heterotrophic growth conditions
LINKS TO OTHER DATABASES (specific for Metallosphaera sedula DSM 5348)
SILVA: 16S/18S rRNA, 23S/28S rRNA
: 16645
