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Information on Organism Brugia malayi

agent of lymphatic filariasis; Brugia malayi (Brug, 1927); Brugia malayi;

TaxTree of Organism Brugia malayi

Condensed Tree View

cellular organisms

can be found in Brenda

BRENDA pathways

(superkingdom)

Opisthokonta can be found in Brenda

can be found in Brenda

BRENDA pathways

(clade)

can be found in Brenda

BRENDA pathways

(kingdom)

can be found in Brenda

BRENDA pathways

(clade)

can be found in Brenda

BRENDA pathways

(clade)

Protostomia can be found in Brenda

can be found in Brenda

BRENDA pathways

(clade)

can be found in Brenda

BRENDA pathways

(clade)

can be found in Brenda

BRENDA pathways

(phylum)

Chromadorea can be found in Brenda

can be found in Brenda

BRENDA pathways

(class)

Rhabditida can be found in Brenda

can be found in Brenda

BRENDA pathways

(order)

can be found in Brenda

BRENDA pathways

(suborder)

Spiruromorpha can be found in Brenda

can be found in Brenda

(infraorder)

Filarioidea can be found in Brenda

can be found in Brenda

BRENDA pathways

(superfamily)

Onchocercidae can be found in Brenda

can be found in Brenda

BRENDA pathways

(family)

can be found in Brenda

BRENDA pathways

(genus)

can be found in Brenda

BRENDA pathways

(species)

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(R)-cysteate degradation

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(S)-lactate fermentation to propanoate, acetate and hydrogen

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(S)-reticuline biosynthesis I

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1,3-propanediol biosynthesis (engineered)

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1,5-anhydrofructose degradation

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1-butanol autotrophic biosynthesis (engineered)

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15-epi-lipoxin biosynthesis

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2'-deoxymugineic acid phytosiderophore biosynthesis

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2,3-dihydroxybenzoate biosynthesis

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2-carboxy-1,4-naphthoquinol biosynthesis

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2-deoxy-D-glucose 6-phosphate degradation

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3-(4-hydroxyphenyl)pyruvate biosynthesis

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3-dehydroquinate biosynthesis II (archaea)

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3-hydroxy-4-methyl-anthranilate biosynthesis I

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3-hydroxy-4-methyl-anthranilate biosynthesis II

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3-phosphoinositide biosynthesis

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4-hydroxy-2-nonenal detoxification

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4-hydroxybenzoate biosynthesis I (eukaryotes)

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acetone degradation I (to methylglyoxal)

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acetone degradation III (to propane-1,2-diol)

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adenosine deoxyribonucleotides de novo biosynthesis

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adenosine deoxyribonucleotides de novo biosynthesis II

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adenosine ribonucleotides de novo biosynthesis

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aerobic respiration (NDH-1 to cytochrome c oxidase via plastocyanin)

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aerobic respiration I (cytochrome c)

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aerobic respiration II (cytochrome c) (yeast)

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aerobic respiration III (alternative oxidase pathway)

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aerobic respiration in cyanobacteria (NDH-2 to cytochrome c oxidase via plastocyanin)

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Aflatoxin biosynthesis

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alanine metabolism

alanine metabolism

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Alanine, aspartate and glutamate metabolism

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allantoin degradation

allantoin degradation

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alpha-Linolenic acid metabolism

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Amaryllidacea alkaloids biosynthesis

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Amino sugar and nucleotide sugar metabolism

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Aminoacyl-tRNA biosynthesis

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Aminobenzoate degradation

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ammonia oxidation II (anaerobic)

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anaerobic energy metabolism (invertebrates, cytosol)

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anandamide lipoxygenation

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anhydromuropeptides recycling I

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Arachidonic acid metabolism

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arachidonic acid metabolism

arachidonic acid metabolism

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Arginine and proline metabolism

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Arginine biosynthesis

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arginine metabolism

arginine metabolism

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aromatic biogenic amine degradation (bacteria)

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arsenite oxidation I (respiratory)

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Ascorbate and aldarate metabolism

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ascorbate recycling (cytosolic)

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aspartate and asparagine metabolism

aspartate and asparagine metabolism

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aspirin triggered resolvin D biosynthesis

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aspirin triggered resolvin E biosynthesis

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atromentin biosynthesis

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bacterial bioluminescence

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baicalein degradation (hydrogen peroxide detoxification)

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beta-Alanine metabolism

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Betalain biosynthesis

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betanidin degradation

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betaxanthin biosynthesis

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betaxanthin biosynthesis (via dopamine)

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Bifidobacterium shunt

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Biosynthesis of secondary metabolites

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Biosynthesis of siderophore group nonribosomal peptides

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bupropion degradation

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Butanoate metabolism

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C20 prostanoid biosynthesis

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C4 and CAM-carbon fixation

C4 and CAM-carbon fixation

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C4 photosynthetic carbon assimilation cycle, NAD-ME type

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C4 photosynthetic carbon assimilation cycle, NADP-ME type

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C4 photosynthetic carbon assimilation cycle, PEPCK type

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C5-Branched dibasic acid metabolism

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caffeine degradation III (bacteria, via demethylation)

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Caffeine metabolism

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Calvin-Benson-Bassham cycle

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camalexin biosynthesis

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canavanine degradation

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Carbon fixation in photosynthetic organisms

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Carbon fixation pathways in prokaryotes

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catecholamine biosynthesis

CDP-6-deoxy-D-gulose biosynthesis

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cellulose degradation

cellulose degradation

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cellulose degradation II (fungi)

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chitin biosynthesis

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chitin degradation I (archaea)

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chitin degradation II (Vibrio)

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chitin degradation III (Serratia)

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chorismate biosynthesis from 3-dehydroquinate

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chorismate metabolism

chorismate metabolism

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cis-zeatin biosynthesis

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Citrate cycle (TCA cycle)

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citric acid cycle

citric acid cycle

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CMP phosphorylation

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CO2 fixation in Crenarchaeota

CO2 fixation in Crenarchaeota

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coenzyme M biosynthesis

coenzyme M biosynthesis

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coenzyme M biosynthesis II

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cyanate degradation

cyanate degradation

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Cyanoamino acid metabolism

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Cysteine and methionine metabolism

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cysteine metabolism

cysteine metabolism

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cytosolic NADPH production (yeast)

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D-galactose degradation I (Leloir pathway)

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D-Glutamine and D-glutamate metabolism

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D-sorbitol biosynthesis I

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degradation of hexoses

degradation of hexoses

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denitrification

denitrification

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diethylphosphate degradation

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dipicolinate biosynthesis

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divinyl ether biosynthesis II

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dopamine degradation

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Drug metabolism - cytochrome P450

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Drug metabolism - other enzymes

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dTMP de novo biosynthesis (mitochondrial)

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ectoine biosynthesis

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enterobactin biosynthesis

enterobactin biosynthesis

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Entner Doudoroff pathway

Entner Doudoroff pathway

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Entner-Doudoroff pathway I

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Entner-Doudoroff pathway II (non-phosphorylative)

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Entner-Doudoroff pathway III (semi-phosphorylative)

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ergothioneine biosynthesis I (bacteria)

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ethanol degradation IV

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ethene biosynthesis I (plants)

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ethene biosynthesis III (microbes)

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ethene biosynthesis V (engineered)

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eumelanin biosynthesis

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Fatty acid biosynthesis

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fatty acid biosynthesis initiation (mitochondria)

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fatty acid biosynthesis initiation (type I)

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Fatty acid degradation

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Fe(II) oxidation

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Folate biosynthesis

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folate transformations II (plants)

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folate transformations III (E. coli)

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formaldehyde assimilation I (serine pathway)

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formaldehyde assimilation II (assimilatory RuMP Cycle)

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formaldehyde assimilation III (dihydroxyacetone cycle)

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formaldehyde oxidation I

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formate to nitrite electron transfer

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fructan degradation

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Fructose and mannose metabolism

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Galactose metabolism

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gamma-glutamyl cycle

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GDP-alpha-D-glucose biosynthesis

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GDP-mannose biosynthesis

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gliotoxin biosynthesis

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gluconeogenesis

gluconeogenesis

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gluconeogenesis I

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gluconeogenesis II (Methanobacterium thermoautotrophicum)

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gluconeogenesis III

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glucose and glucose-1-phosphate degradation

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GLUCOSE1PMETAB-PWY

glucosylglycerol biosynthesis

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glutamate and glutamine metabolism

glutamate and glutamine metabolism

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glutathione biosynthesis

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GLUTATHIONESYN-PWY

Glutathione metabolism

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glutathione metabolism

glutathione metabolism

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glutathione-mediated detoxification I

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glutathione-mediated detoxification II

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glutathione-peroxide redox reactions

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glycerol degradation to butanol

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Glycerolipid metabolism

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Glycerophospholipid metabolism

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Glycine, serine and threonine metabolism

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glycogen biosynthesis I (from ADP-D-Glucose)

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GLYCOGENSYNTH-PWY

glycogen biosynthesis III (from alpha-maltose 1-phosphate)

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glycogen degradation I

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glycogen degradation II

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glycogen metabolism

glycogen metabolism

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glycolysis

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Glycolysis / Gluconeogenesis

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glycolysis I (from glucose 6-phosphate)

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glycolysis II (from fructose 6-phosphate)

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glycolysis III (from glucose)

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ANAGLYCOLYSIS-PWY

glycolysis IV

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glycolysis V (Pyrococcus)

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Glycosaminoglycan degradation

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Glycosphingolipid biosynthesis - ganglio series

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Glycosphingolipid biosynthesis - globo and isoglobo series

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Glyoxylate and dicarboxylate metabolism

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gossypol biosynthesis

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grixazone biosynthesis

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guanosine deoxyribonucleotides de novo biosynthesis I

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guanosine deoxyribonucleotides de novo biosynthesis II

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guanosine ribonucleotides de novo biosynthesis

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heme b biosynthesis I (aerobic)

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HEME-BIOSYNTHESIS-II

heme b biosynthesis II (oxygen-independent)

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heme b biosynthesis V (aerobic)

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HEME-BIOSYNTHESIS-II-1

heme degradation I

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heme metabolism

heme metabolism

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heterolactic fermentation

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Histidine metabolism

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homoglutathione biosynthesis

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hypoglycin biosynthesis

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indole glucosinolate activation (intact plant cell)

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Inositol phosphate metabolism

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isoprenoid biosynthesis

isoprenoid biosynthesis

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Isoquinoline alkaloid biosynthesis

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jadomycin biosynthesis

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jasmonic acid biosynthesis

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justicidin B biosynthesis

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L-alanine biosynthesis II

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ALANINE-SYN2-PWY

L-alanine degradation II (to D-lactate)

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L-alanine degradation III

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ALANINE-DEG3-PWY

L-alanine degradation V (oxidative Stickland reaction)

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L-alanine degradation VI (reductive Stickland reaction)

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L-arginine degradation I (arginase pathway)

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L-arginine degradation VI (arginase 2 pathway)

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L-arginine degradation VII (arginase 3 pathway)

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L-asparagine degradation III (mammalian)

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ASPARAGINE-DEG1-PWY-1

L-aspartate biosynthesis

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ASPARTATESYN-PWY

L-aspartate degradation I

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ASPARTATE-DEG1-PWY

L-citrulline biosynthesis

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L-cysteine biosynthesis I

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L-dopa degradation II (bacterial)

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L-glutamate degradation II

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L-glutamate degradation VI (to pyruvate)

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L-glutamine biosynthesis III

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L-histidine degradation V

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L-homoserine biosynthesis

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L-lactaldehyde degradation

L-lactaldehyde degradation

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L-lysine biosynthesis I

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DAPLYSINESYN-PWY

L-lysine biosynthesis II

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L-lysine biosynthesis III

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L-lysine biosynthesis VI

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L-methionine biosynthesis IV

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L-methionine degradation I (to L-homocysteine)

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METHIONINE-DEG1-PWY

L-Ndelta-acetylornithine biosynthesis

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L-nicotianamine biosynthesis

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L-phenylalanine biosynthesis I

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L-phenylalanine degradation II (anaerobic)

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L-phenylalanine degradation III

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L-phenylalanine degradation IV (mammalian, via side chain)

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L-phenylalanine degradation VI (reductive Stickland reaction)

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L-serine biosynthesis I

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L-tryptophan degradation I (via anthranilate)

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L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde

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L-tryptophan degradation VI (via tryptamine)

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L-tryptophan degradation X (mammalian, via tryptamine)

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L-tryptophan degradation XI (mammalian, via kynurenine)

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L-tyrosine biosynthesis I

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L-tyrosine degradation I

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L-tyrosine degradation II

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L-tyrosine degradation III

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L-tyrosine degradation IV (to 4-methylphenol)

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L-tyrosine degradation V (reductive Stickland reaction)

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lactate fermentation

lactate fermentation

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lactose degradation II

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LACTOSEUTIL-PWY

leukotriene biosynthesis

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Linoleic acid metabolism

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lipid metabolism

lipid metabolism

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lipoprotein posttranslational modification

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lipoxin biosynthesis

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luteolin triglucuronide degradation

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Lysine biosynthesis

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malate/L-aspartate shuttle pathway

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MALATE-ASPARTATE-SHUTTLE-PWY

matairesinol biosynthesis

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melatonin degradation I

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melatonin degradation II

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melibiose degradation

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Metabolic pathways

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metabolism of disaccharids

metabolism of disaccharids

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Metabolism of xenobiotics by cytochrome P450

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Methane metabolism

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methanol oxidation to formaldehyde IV

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methionine metabolism

methionine metabolism

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methyl indole-3-acetate interconversion

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methylaspartate cycle

methylerythritol phosphate pathway I

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methylerythritol phosphate pathway II

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methylsalicylate degradation

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Microbial metabolism in diverse environments

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mixed acid fermentation

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FERMENTATION-PWY

Monobactam biosynthesis

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mycolate biosynthesis

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mycolyl-arabinogalactan-peptidoglycan complex biosynthesis

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NAD metabolism

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Neomycin, kanamycin and gentamicin biosynthesis

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nicotine degradation IV

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nicotine degradation V

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nitrate reduction I (denitrification)

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DENITRIFICATION-PWY

nitrate reduction VII (denitrification)

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nitrate reduction X (dissimilatory, periplasmic)

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nitric oxide biosynthesis II (mammals)

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nitrifier denitrification

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nitrite-dependent anaerobic methane oxidation

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Nitrogen metabolism

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nocardicin A biosynthesis

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non-pathway related

non-pathway related

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noradrenaline and adrenaline degradation

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norspermidine biosynthesis

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Novobiocin biosynthesis

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O-antigen building blocks biosynthesis (E. coli)

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O-Antigen nucleotide sugar biosynthesis

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o-diquinones biosynthesis

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oleandomycin activation/inactivation

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One carbon pool by folate

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ophthalmate biosynthesis

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Other glycan degradation

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Other types of O-glycan biosynthesis

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Oxidative phosphorylation

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oxidative phosphorylation

oxidative phosphorylation

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Pantothenate and CoA biosynthesis

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pantothenate biosynthesis

pantothenate biosynthesis

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partial TCA cycle (obligate autotrophs)

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pentachlorophenol degradation

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Pentose and glucuronate interconversions

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Pentose phosphate pathway

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pentose phosphate pathway

pentose phosphate pathway

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pentose phosphate pathway (non-oxidative branch) II

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pentose phosphate pathway (oxidative branch) I

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OXIDATIVEPENT-PWY

Peptidoglycan biosynthesis

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peptidoglycan biosynthesis

peptidoglycan biosynthesis

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peptidoglycan biosynthesis II (staphylococci)

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peptidoglycan biosynthesis IV (Enterococcus faecium)

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peptidoglycan maturation (meso-diaminopimelate containing)

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Phenylalanine metabolism

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Phenylalanine, tyrosine and tryptophan biosynthesis

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Phenylpropanoid biosynthesis

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phosphate acquisition

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phosphopantothenate biosynthesis I

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photosynthesis

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photosynthetic 3-hydroxybutanoate biosynthesis (engineered)

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platensimycin biosynthesis

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polyamine pathway

polyamine pathway

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Porphyrin and chlorophyll metabolism

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ppGpp metabolism

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procollagen hydroxylation and glycosylation

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Propanoate metabolism

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propionate fermentation

propionate fermentation

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protein ubiquitination

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purine deoxyribonucleosides salvage

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Purine metabolism

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purine metabolism

purine metabolism

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putrescine biosynthesis III

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putrescine degradation III

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pyrimidine deoxyribonucleosides degradation

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pyrimidine deoxyribonucleosides salvage

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pyrimidine deoxyribonucleotide phosphorylation

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pyrimidine deoxyribonucleotides biosynthesis from CTP

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pyrimidine deoxyribonucleotides de novo biosynthesis I

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pyrimidine deoxyribonucleotides de novo biosynthesis II

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pyrimidine deoxyribonucleotides de novo biosynthesis III

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pyrimidine deoxyribonucleotides de novo biosynthesis IV

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Pyrimidine metabolism

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pyrimidine metabolism

pyrimidine metabolism

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pyrimidine ribonucleosides degradation

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pyrimidine ribonucleosides salvage I

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pyrimidine ribonucleosides salvage II

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pyruvate fermentation to (S)-lactate

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Pyruvate metabolism

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reactive oxygen species degradation

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resolvin D biosynthesis

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retinol biosynthesis

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Retinol metabolism

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Riboflavin metabolism

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rosmarinic acid biosynthesis I

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Rubisco shunt

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S-adenosyl-L-methionine biosynthesis

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S-adenosyl-L-methionine salvage I

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S-adenosyl-L-methionine salvage II

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salicylate biosynthesis I

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salidroside biosynthesis

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saponin biosynthesis II

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sedoheptulose bisphosphate bypass

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seleno-amino acid biosynthesis (plants)

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Selenocompound metabolism

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serine metabolism

serine metabolism

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serotonin and melatonin biosynthesis

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serotonin degradation

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sesamin biosynthesis

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spermidine biosynthesis II

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Sphingolipid metabolism

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stachyose degradation

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Starch and sucrose metabolism

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starch biosynthesis

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starch degradation III

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starch degradation V

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Steroid hormone biosynthesis

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streptomycin biosynthesis

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Streptomycin biosynthesis

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succinate to cytochrome bd oxidase electron transfer

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succinate to cytochrome bo oxidase electron transfer

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sucrose biosynthesis I (from photosynthesis)

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sucrose biosynthesis II

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sucrose biosynthesis III

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sucrose degradation II (sucrose synthase)

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sucrose degradation III (sucrose invertase)

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sucrose degradation IV (sucrose phosphorylase)

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sucrose degradation V (sucrose alpha-glucosidase)

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sulfolactate degradation III

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sulfopterin metabolism

sulfopterin metabolism

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Sulfur metabolism

-

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superoxide radicals degradation

-

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superpathway of glucose and xylose degradation

-

-

superpathway of glycolysis and the Entner-Doudoroff pathway

-

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superpathway of glyoxylate cycle and fatty acid degradation

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superpathway of methylsalicylate metabolism

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superpathway of ornithine degradation

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superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)

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superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis

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Taurine and hypotaurine metabolism

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TCA cycle I (prokaryotic)

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TCA cycle II (plants and fungi)

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TCA cycle III (animals)

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TCA cycle IV (2-oxoglutarate decarboxylase)

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TCA cycle V (2-oxoglutarate synthase)

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TCA cycle VII (acetate-producers)

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Terpenoid backbone biosynthesis

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tetrahydrofolate biosynthesis

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tetrahydrofolate metabolism

tetrahydrofolate metabolism

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theophylline degradation

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Thiamine metabolism

-

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thioredoxin pathway

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threonine metabolism

threonine metabolism

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thyroid hormone metabolism II (via conjugation and/or degradation)

-

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traumatin and (Z)-3-hexen-1-yl acetate biosynthesis

-

-

trehalose biosynthesis I

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trehalose biosynthesis II

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trehalose biosynthesis III

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TREHALOSESYN-PWY

trehalose degradation I (low osmolarity)

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trehalose degradation II (cytosolic)

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trehalose degradation IV

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trehalose degradation V

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trehalose degradation VI (periplasmic)

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triacylglycerol degradation

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tRNA charging

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TRNA-CHARGING-PWY

tRNA processing

-

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Tropane, piperidine and pyridine alkaloid biosynthesis

-

-

Tryptophan metabolism

-

-

tryptophan metabolism

tryptophan metabolism

-

-

Tyrosine metabolism

-

-

tyrosine metabolism

tyrosine metabolism

-

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Ubiquinone and other terpenoid-quinone biosynthesis

-

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UDP-alpha-D-galactofuranose biosynthesis

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UDP-alpha-D-glucose biosynthesis

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UDP-N-acetyl-D-galactosamine biosynthesis II

-

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UDP-N-acetyl-D-galactosamine biosynthesis III

-

-

UDP-N-acetyl-D-glucosamine biosynthesis I

-

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UDP-N-acetyl-D-glucosamine biosynthesis II

-

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UDPNACETYLGALSYN-PWY

UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)

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UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)

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UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)

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-

urate conversion to allantoin I

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urate conversion to allantoin II

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urate conversion to allantoin III

-

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urea cycle

UTP and CTP de novo biosynthesis

-

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vanillin biosynthesis I

-

-

vitamin B1 metabolism

vitamin B1 metabolism

-

-

vitamin K metabolism

vitamin K metabolism

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xyloglucan degradation II (exoglucanase)

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Zeatin biosynthesis

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early embryos contain large amounts of Bm-chs-1 transcripts, later stage embryos within the maternal uterus show little or no Bm-chs-1 transcripts

Manually annotated by BRENDA team

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female and male adult worms

Manually annotated by BRENDA team

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Manually annotated by BRENDA team

additional information

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Manually annotated by BRENDA team

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Manually annotated by BRENDA team

chitinase is stored and secreted from the inner body of microfilariae via either the pharyngeal thread, or during transmission of the microfilariae to the vector, contained in vesicle-like structures

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Manually annotated by BRENDA team

microfilarial stage

chitinase is stored and secreted from the inner body of microfilariae

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Manually annotated by BRENDA team

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NCBI: Taxonomy, PubMed, Genome

SILVA: 16S/18S rRNA, 23S/28S rRNA