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Information on Organism Brugia malayi

agent of lymphatic filariasis; Brugia malayi (Brug, 1927); Brugia malayi;

TaxTree of Organism Brugia malayi

Condensed Tree View

cellular organisms

can be found in Brenda

BRENDA pathways

(superkingdom)

Opisthokonta can be found in Brenda

can be found in Brenda

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(clade)

can be found in Brenda

BRENDA pathways

(kingdom)

can be found in Brenda

BRENDA pathways

(clade)

can be found in Brenda

BRENDA pathways

(clade)

Protostomia can be found in Brenda

can be found in Brenda

BRENDA pathways

(clade)

can be found in Brenda

BRENDA pathways

(clade)

can be found in Brenda

BRENDA pathways

(phylum)

Chromadorea can be found in Brenda

can be found in Brenda

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(class)

Rhabditida can be found in Brenda

can be found in Brenda

BRENDA pathways

(order)

can be found in Brenda

BRENDA pathways

(suborder)

Spiruromorpha can be found in Brenda

can be found in Brenda

(infraorder)

Filarioidea can be found in Brenda

can be found in Brenda

BRENDA pathways

(superfamily)

Onchocercidae can be found in Brenda

can be found in Brenda

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(family)

can be found in Brenda

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(genus)

can be found in Brenda

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(species)

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(S)-lactate fermentation to propanoate, acetate and hydrogen

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Bifidobacterium shunt

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Biosynthesis of secondary metabolites

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Cysteine and methionine metabolism

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Glycolysis / Gluconeogenesis

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heterolactic fermentation

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L-histidine degradation V

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L-lactaldehyde degradation

L-lactaldehyde degradation

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lactate fermentation

lactate fermentation

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Metabolic pathways

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Microbial metabolism in diverse environments

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Propanoate metabolism

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pyruvate fermentation to (S)-lactate

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Pyruvate metabolism

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superpathway of glucose and xylose degradation

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cytosolic NADPH production (yeast)

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Entner-Doudoroff pathway I

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formaldehyde oxidation I

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Glutathione metabolism

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Pentose phosphate pathway

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pentose phosphate pathway

pentose phosphate pathway

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pentose phosphate pathway (oxidative branch) I

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OXIDATIVEPENT-PWY

superpathway of glycolysis and the Entner-Doudoroff pathway

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2-deoxy-D-glucose 6-phosphate degradation

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3-dehydroquinate biosynthesis II (archaea)

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cremeomycin biosynthesis

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dipicolinate biosynthesis

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ectoine biosynthesis

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Glycine, serine and threonine metabolism

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grixazone biosynthesis

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L-homoserine biosynthesis

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L-lysine biosynthesis I

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DAPLYSINESYN-PWY

L-lysine biosynthesis II

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L-lysine biosynthesis III

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L-lysine biosynthesis VI

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L-methionine biosynthesis IV

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Lysine biosynthesis

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Monobactam biosynthesis

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norspermidine biosynthesis

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platensimycin biosynthesis

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spermidine biosynthesis II

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threonine metabolism

threonine metabolism

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Carbon fixation in photosynthetic organisms

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photosynthesis

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aerobic respiration I (cytochrome c)

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aerobic respiration II (cytochrome c) (yeast)

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aerobic respiration III (alternative oxidase pathway)

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Butanoate metabolism

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Carbon fixation pathways in prokaryotes

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Citrate cycle (TCA cycle)

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citric acid cycle

citric acid cycle

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methylaspartate cycle

Oxidative phosphorylation

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partial TCA cycle (obligate autotrophs)

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propionate fermentation

propionate fermentation

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succinate to chytochrome c oxidase via cytochrome c6

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succinate to cytochrome bd oxidase electron transfer

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succinate to cytochrome bo oxidase electron transfer

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succinate to cytochrome c oxidase via plastocyanin

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succinate to plastoquinol oxidase

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superpathway of glyoxylate cycle and fatty acid degradation

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TCA cycle I (prokaryotic)

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TCA cycle II (plants and fungi)

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TCA cycle III (animals)

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TCA cycle IV (2-oxoglutarate decarboxylase)

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TCA cycle V (2-oxoglutarate synthase)

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TCA cycle VII (acetate-producers)

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TCA cycle VIII (Chlamydia)

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Arginine and proline metabolism

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aromatic biogenic amine degradation (bacteria)

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dopamine degradation

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Drug metabolism - cytochrome P450

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Histidine metabolism

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Isoquinoline alkaloid biosynthesis

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L-phenylalanine degradation IV (mammalian, via side chain)

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L-tryptophan degradation VI (via tryptamine)

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L-tryptophan degradation X (mammalian, via tryptamine)

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melatonin degradation II

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noradrenaline and adrenaline degradation

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Phenylalanine metabolism

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putrescine degradation III

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salidroside biosynthesis

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serotonin degradation

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serotonin metabolism

serotonin metabolism

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Tryptophan metabolism

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tryptophan metabolism

tryptophan metabolism

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Tyrosine metabolism

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tyrosine metabolism

tyrosine metabolism

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dTMP de novo biosynthesis (mitochondrial)

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Folate biosynthesis

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folate transformations II (plants)

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folate transformations III (E. coli)

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One carbon pool by folate

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tetrahydrofolate biosynthesis

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tetrahydrofolate metabolism

tetrahydrofolate metabolism

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Ascorbate and aldarate metabolism

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ascorbate recycling (cytosolic)

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ammonia oxidation II (anaerobic)

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denitrification

denitrification

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nitrate reduction I (denitrification)

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DENITRIFICATION-PWY

nitrate reduction VII (denitrification)

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nitrifier denitrification

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nitrite-dependent anaerobic methane oxidation

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Nitrogen metabolism

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glutathione metabolism

glutathione metabolism

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glutathione-peroxide redox reactions

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non-pathway related

non-pathway related

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Selenocompound metabolism

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thioredoxin pathway

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o-diquinones biosynthesis

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gossypol biosynthesis

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justicidin B biosynthesis

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matairesinol biosynthesis

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sesamin biosynthesis

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ethanol degradation IV

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Glyoxylate and dicarboxylate metabolism

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methanol oxidation to formaldehyde IV

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reactive oxygen species degradation

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superoxide radicals degradation

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baicalein degradation (hydrogen peroxide detoxification)

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betanidin degradation

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luteolin triglucuronide degradation

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Phenylpropanoid biosynthesis

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xanthommatin biosynthesis

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Arachidonic acid metabolism

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arachidonic acid metabolism

arachidonic acid metabolism

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Drug metabolism - other enzymes

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alpha-Linolenic acid metabolism

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divinyl ether biosynthesis II

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jasmonic acid biosynthesis

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Linoleic acid metabolism

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traumatin and (Z)-3-hexen-1-yl acetate biosynthesis

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15-epi-lipoxin biosynthesis

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anandamide lipoxygenation

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aspirin triggered resolvin D biosynthesis

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aspirin triggered resolvin E biosynthesis

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leukotriene biosynthesis

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lipoxin biosynthesis

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resolvin D biosynthesis

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3-hydroxy-4-methyl-anthranilate biosynthesis I

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3-hydroxy-4-methyl-anthranilate biosynthesis II

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L-tryptophan degradation I (via anthranilate)

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L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde

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L-tryptophan degradation XI (mammalian, via kynurenine)

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lipid metabolism

lipid metabolism

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procollagen hydroxylation and glycosylation

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Arginine biosynthesis

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nitric oxide biosynthesis II (mammals)

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1,5-anhydrofructose degradation

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acetone degradation I (to methylglyoxal)

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acetone degradation III (to propane-1,2-diol)

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Amaryllidacea alkaloids biosynthesis

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Aminobenzoate degradation

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bupropion degradation

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Caffeine metabolism

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Fatty acid degradation

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melatonin degradation I

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Metabolism of xenobiotics by cytochrome P450

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nicotine degradation IV

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nicotine degradation V

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Retinol metabolism

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Steroid hormone biosynthesis

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vanillin biosynthesis I

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bacterial bioluminescence

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C20 prostanoid biosynthesis

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ethene biosynthesis III (microbes)

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Porphyrin and chlorophyll metabolism

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caffeine degradation III (bacteria, via demethylation)

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Purine metabolism

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theophylline degradation

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pyrimidine deoxyribonucleosides salvage

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pyrimidine deoxyribonucleotides biosynthesis from CTP

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pyrimidine deoxyribonucleotides de novo biosynthesis I

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pyrimidine deoxyribonucleotides de novo biosynthesis II

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pyrimidine deoxyribonucleotides de novo biosynthesis IV

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Pyrimidine metabolism

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pyrimidine metabolism

pyrimidine metabolism

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superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)

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Glycerophospholipid metabolism

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D-Amino acid metabolism

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Cyanoamino acid metabolism

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gamma-glutamyl cycle

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hypoglycin biosynthesis

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Taurine and hypotaurine metabolism

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protein ubiquitination

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metabolism of disaccharids

metabolism of disaccharids

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Starch and sucrose metabolism

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trehalose biosynthesis I

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Amino sugar and nucleotide sugar metabolism

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chitin biosynthesis

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heme degradation I

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Pentose and glucuronate interconversions

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saponin biosynthesis II

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thyroid hormone metabolism II (via conjugation and/or degradation)

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Other types of O-glycan biosynthesis

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NAD metabolism

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2'-deoxymugineic acid phytosiderophore biosynthesis

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ethene biosynthesis I (plants)

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L-methionine degradation I (to L-homocysteine)

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METHIONINE-DEG1-PWY

methionine metabolism

methionine metabolism

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S-adenosyl-L-methionine biosynthesis

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S-adenosyl-L-methionine salvage I

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S-adenosyl-L-methionine salvage II

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anhydromuropeptides recycling I

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Peptidoglycan biosynthesis

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peptidoglycan biosynthesis

peptidoglycan biosynthesis

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UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)

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UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)

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UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)

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4-hydroxy-2-nonenal detoxification

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camalexin biosynthesis

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gliotoxin biosynthesis

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glutathione-mediated detoxification I

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glutathione-mediated detoxification II

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indole glucosinolate activation (intact plant cell)

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pentachlorophenol degradation

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chorismate biosynthesis from 3-dehydroquinate

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chorismate metabolism

chorismate metabolism

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Phenylalanine, tyrosine and tryptophan biosynthesis

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L-nicotianamine biosynthesis

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cysteine metabolism

cysteine metabolism

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L-cysteine biosynthesis I

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seleno-amino acid biosynthesis (plants)

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Sulfur metabolism

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Terpenoid backbone biosynthesis

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cis-zeatin biosynthesis

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Zeatin biosynthesis

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(R)-cysteate degradation

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(S)-reticuline biosynthesis I

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3-(4-hydroxyphenyl)pyruvate biosynthesis

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4-hydroxybenzoate biosynthesis I (eukaryotes)

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Alanine, aspartate and glutamate metabolism

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anaerobic energy metabolism (invertebrates, cytosol)

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aspartate and asparagine metabolism

aspartate and asparagine metabolism

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atromentin biosynthesis

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C4 and CAM-carbon fixation

C4 and CAM-carbon fixation

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C4 photosynthetic carbon assimilation cycle, NAD-ME type

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C4 photosynthetic carbon assimilation cycle, PEPCK type

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coenzyme M biosynthesis

coenzyme M biosynthesis

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coenzyme M biosynthesis II

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gluconeogenesis

gluconeogenesis

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glutamate and glutamine metabolism

glutamate and glutamine metabolism

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indole-3-acetate biosynthesis II

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indole-3-acetate biosynthesis VI (bacteria)

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L-asparagine degradation III (mammalian)

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ASPARAGINE-DEG1-PWY-1

L-aspartate biosynthesis

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ASPARTATESYN-PWY

L-aspartate degradation I

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ASPARTATE-DEG1-PWY

L-glutamate degradation II

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L-phenylalanine biosynthesis I

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L-phenylalanine degradation II (anaerobic)

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L-phenylalanine degradation III

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L-phenylalanine degradation VI (reductive Stickland reaction)

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L-tryptophan degradation IV (via indole-3-lactate)

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L-tryptophan degradation VIII (to tryptophol)

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L-tryptophan degradation XIII (reductive Stickland reaction)

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L-tyrosine biosynthesis I

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L-tyrosine degradation I

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L-tyrosine degradation II

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L-tyrosine degradation III

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L-tyrosine degradation IV (to 4-methylphenol)

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L-tyrosine degradation V (reductive Stickland reaction)

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malate/L-aspartate shuttle pathway

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MALATE-ASPARTATE-SHUTTLE-PWY

Novobiocin biosynthesis

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rosmarinic acid biosynthesis I

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sulfolactate degradation III

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Tropane, piperidine and pyridine alkaloid biosynthesis

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alanine metabolism

alanine metabolism

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L-alanine biosynthesis II

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ALANINE-SYN2-PWY

L-alanine degradation II (to D-lactate)

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L-alanine degradation III

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ALANINE-DEG3-PWY

L-alanine degradation V (oxidative Stickland reaction)

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L-alanine degradation VI (reductive Stickland reaction)

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1,3-propanediol biosynthesis (engineered)

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Fructose and mannose metabolism

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Galactose metabolism

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GDP-alpha-D-glucose biosynthesis

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glucose and glucose-1-phosphate degradation

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GLUCOSE1PMETAB-PWY

glycogen degradation I

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glycogen degradation II

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glycolysis

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glycolysis III (from glucose)

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ANAGLYCOLYSIS-PWY

Neomycin, kanamycin and gentamicin biosynthesis

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Streptomycin biosynthesis

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sucrose biosynthesis II

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sucrose degradation III (sucrose invertase)

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trehalose degradation I (low osmolarity)

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trehalose degradation II (cytosolic)

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trehalose degradation IV

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trehalose degradation V

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UDP-N-acetyl-D-galactosamine biosynthesis II

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UDP-N-acetyl-D-glucosamine biosynthesis II

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UDPNACETYLGALSYN-PWY

1-butanol autotrophic biosynthesis (engineered)

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Entner-Doudoroff pathway II (non-phosphorylative)

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Entner-Doudoroff pathway III (semi-phosphorylative)

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gluconeogenesis II (Methanobacterium thermoautotrophicum)

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glycerol degradation to butanol

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glycolysis I (from glucose 6-phosphate)

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glycolysis II (from fructose 6-phosphate)

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glycolysis IV

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glycolysis V (Pyrococcus)

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mixed acid fermentation

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FERMENTATION-PWY

photosynthetic 3-hydroxybutanoate biosynthesis (engineered)

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Rubisco shunt

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3-phosphoinositide biosynthesis

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Inositol phosphate metabolism

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Calvin-Benson-Bassham cycle

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formaldehyde assimilation III (dihydroxyacetone cycle)

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gluconeogenesis I

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gluconeogenesis III

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sucrose biosynthesis I (from photosynthesis)

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adenosine ribonucleotides de novo biosynthesis

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purine metabolism

purine metabolism

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Thiamine metabolism

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adenosine deoxyribonucleotides de novo biosynthesis I

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adenosine deoxyribonucleotides de novo biosynthesis II

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CMP phosphorylation

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dZTP biosynthesis

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guanosine deoxyribonucleotides de novo biosynthesis I

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guanosine deoxyribonucleotides de novo biosynthesis II

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guanosine ribonucleotides de novo biosynthesis

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ppGpp metabolism

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purine deoxyribonucleosides salvage

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pyrimidine deoxyribonucleotide phosphorylation

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pyrimidine deoxyribonucleotides de novo biosynthesis III

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UTP and CTP de novo biosynthesis

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C4 photosynthetic carbon assimilation cycle, NADP-ME type

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nitrogen remobilization from senescing leaves

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methyl indole-3-acetate interconversion

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methylsalicylate degradation

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retinol biosynthesis

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superpathway of methylsalicylate metabolism

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Glycerolipid metabolism

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triacylglycerol degradation

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diethylphosphate degradation

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sulfopterin metabolism

sulfopterin metabolism

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phosphate acquisition

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Riboflavin metabolism

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vitamin B1 metabolism

vitamin B1 metabolism

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L-serine biosynthesis I

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Methane metabolism

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serine metabolism

serine metabolism

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glycogen biosynthesis III (from alpha-maltose 1-phosphate)

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mycolate biosynthesis

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trehalose biosynthesis II

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trehalose biosynthesis III

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TREHALOSESYN-PWY

tRNA processing

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cellulose degradation

cellulose degradation

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cellulose degradation II (fungi)

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chitin degradation I (archaea)

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chitin degradation II (Vibrio)

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chitin degradation III (Serratia)

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Glycosphingolipid biosynthesis - globo and isoglobo series

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melibiose degradation

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Sphingolipid metabolism

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stachyose degradation

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Glycosaminoglycan degradation

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Glycosphingolipid biosynthesis - ganglio series

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lactose degradation II

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LACTOSEUTIL-PWY

Other glycan degradation

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xyloglucan degradation II (exoglucanase)

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trehalose degradation VI (periplasmic)

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fructan degradation

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peptidoglycan biosynthesis II (staphylococci)

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peptidoglycan biosynthesis IV (Enterococcus faecium)

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peptidoglycan maturation (meso-diaminopimelate containing)

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nocardicin A biosynthesis

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lipoprotein posttranslational modification

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allantoin degradation

allantoin degradation

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urate conversion to allantoin I

-

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urate conversion to allantoin II

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urate conversion to allantoin III

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arginine metabolism

arginine metabolism

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canavanine degradation

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L-arginine degradation I (arginase pathway)

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L-arginine degradation VI (arginase 2 pathway)

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L-arginine degradation VII (arginase 3 pathway)

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L-citrulline biosynthesis

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L-Ndelta-acetylornithine biosynthesis

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putrescine biosynthesis III

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urea cycle

pyrimidine deoxyribonucleosides degradation

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pyrimidine ribonucleosides degradation

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-

pyrimidine ribonucleosides salvage I

-

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pyrimidine ribonucleosides salvage II

-

-

polyamine pathway

polyamine pathway

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-

superpathway of ornithine degradation

-

-

(S)-reticuline biosynthesis II

-

-

beta-carboline biosynthesis

-

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Betalain biosynthesis

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betaxanthin biosynthesis

-

-

betaxanthin biosynthesis (via dopamine)

-

-

catecholamine biosynthesis

hydroxycinnamic acid serotonin amides biosynthesis

-

-

hydroxycinnamic acid tyramine amides biosynthesis

-

-

L-dopa degradation II (bacterial)

-

-

methanofuran biosynthesis

-

-

octopamine biosynthesis

-

-

phenylethanol biosynthesis

-

-

psilocybin biosynthesis

-

-

secologanin and strictosidine biosynthesis

-

-

serotonin and melatonin biosynthesis

-

-

formaldehyde assimilation II (assimilatory RuMP Cycle)

-

-

pentose phosphate pathway (non-oxidative branch) II

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-

sedoheptulose bisphosphate bypass

-

-

sucrose degradation V (sucrose alpha-glucosidase)

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ethene biosynthesis V (engineered)

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-

formaldehyde assimilation I (serine pathway)

-

-

cyanate degradation

cyanate degradation

-

-

C5-Branched dibasic acid metabolism

-

-

L-glutamate degradation VI (to pyruvate)

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isoprenoid biosynthesis

isoprenoid biosynthesis

-

-

methylerythritol phosphate pathway I

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methylerythritol phosphate pathway II

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heme b biosynthesis I (aerobic)

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HEME-BIOSYNTHESIS-II

heme b biosynthesis II (oxygen-independent)

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heme b biosynthesis V (aerobic)

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HEME-BIOSYNTHESIS-II-1

heme metabolism

heme metabolism

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D-sorbitol biosynthesis I

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GDP-mannose biosynthesis

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starch biosynthesis

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-

sucrose biosynthesis III

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-

sucrose degradation II (sucrose synthase)

-

-

sucrose degradation IV (sucrose phosphorylase)

-

-

UDP-N-acetyl-D-galactosamine biosynthesis III

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-

UDP-N-acetyl-D-glucosamine biosynthesis I

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-

eumelanin biosynthesis

-

-

CDP-6-deoxy-D-gulose biosynthesis

-

-

D-galactose degradation I (Leloir pathway)

-

-

degradation of hexoses

degradation of hexoses

-

-

dTDP-beta-L-rhamnose biosynthesis

-

-

DTDPRHAMSYN-PWY

glucosylglycerol biosynthesis

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glycogen biosynthesis I (from ADP-D-Glucose)

-

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GLYCOGENSYNTH-PWY

glycogen metabolism

glycogen metabolism

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-

starch degradation III

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-

starch degradation V

-

-

streptomycin biosynthesis

-

-

UDP-alpha-D-glucose biosynthesis

-

-

Entner Doudoroff pathway

Entner Doudoroff pathway

-

-

2,3-dihydroxybenzoate biosynthesis

-

-

2-carboxy-1,4-naphthoquinol biosynthesis

-

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Biosynthesis of siderophore group nonribosomal peptides

-

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enterobactin biosynthesis

enterobactin biosynthesis

-

-

salicylate biosynthesis I

-

-

Ubiquinone and other terpenoid-quinone biosynthesis

-

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vitamin K metabolism

vitamin K metabolism

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mycolyl-arabinogalactan-peptidoglycan complex biosynthesis

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O-antigen building blocks biosynthesis (E. coli)

-

-

O-Antigen nucleotide sugar biosynthesis

-

-

superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis

-

-

UDP-alpha-D-galactofuranose biosynthesis

-

-

Aminoacyl-tRNA biosynthesis

-

-

tRNA charging

-

-

TRNA-CHARGING-PWY

beta-Alanine metabolism

-

-

Pantothenate and CoA biosynthesis

-

-

pantothenate biosynthesis

pantothenate biosynthesis

-

-

phosphopantothenate biosynthesis I

-

-

ergothioneine biosynthesis I (bacteria)

-

-

glutathione biosynthesis

-

-

GLUTATHIONESYN-PWY

homoglutathione biosynthesis

-

-

ophthalmate biosynthesis

-

-

Aflatoxin biosynthesis

-

-

CO2 fixation in Crenarchaeota

CO2 fixation in Crenarchaeota

-

-

Fatty acid biosynthesis

-

-

fatty acid biosynthesis initiation (mitochondria)

-

-

fatty acid biosynthesis initiation (type I)

-

-

jadomycin biosynthesis

-

-

Fe(II) oxidation

-

-

formate to nitrite electron transfer

-

-

nitrate reduction X (dissimilatory, periplasmic)

-

-

oxidative phosphorylation

oxidative phosphorylation

-

-

arsenite to oxygen electron transfer

-

-

arsenite to oxygen electron transfer (via azurin)

-

-

NADPH to cytochrome c oxidase via plastocyanin

-

-

arsenate detoxification I

-

-

oleandomycin activation/inactivation

-

-

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A0A0H5S3P5, A0A4E9EYJ5

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Manually annotated by BRENDA team

early embryos contain large amounts of Bm-chs-1 transcripts, later stage embryos within the maternal uterus show little or no Bm-chs-1 transcripts

Manually annotated by BRENDA team

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female and male adult worms

Manually annotated by BRENDA team

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microfilarial stage

A0A0H5S3P5, A0A4E9EYJ5

highest expression

Manually annotated by BRENDA team

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Manually annotated by BRENDA team

additional information

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-

Manually annotated by BRENDA team

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Manually annotated by BRENDA team

chitinase is stored and secreted from the inner body of microfilariae via either the pharyngeal thread, or during transmission of the microfilariae to the vector, contained in vesicle-like structures

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Manually annotated by BRENDA team

microfilarial stage

chitinase is stored and secreted from the inner body of microfilariae

-

Manually annotated by BRENDA team

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NCBI: Taxonomy, PubMed, Genome

SILVA: 16S/18S rRNA, 23S/28S rRNA

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2022.1 (January 2022)
BRENDA professional