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BRENDA support

Ontology explorer

BTO (BRENDA Tissue Ontology)
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Version 2021-10-23
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Details for pancreatic islet
pancreatic islet
BTO (BRENDA Tissue Ontology) ID
BTO:0000991
BTO:0000991 is linked to 74 enzymes:
Definition
Irregular microscopic structures scattered throughout the pancreas and comprising its endocrine part (the endocrine pancreas). In humans, they are composed of at least four types of cells: the alpha cells, which secrete glucagon; the beta cells, which are the most abundant and secrete insulin; the delta cells, which secrete somatostatin; and the PP cells, which secrete pancreatic polypeptide. Degeneration of the beta cells, whose secretion (insulin) is important in carbohydrate metabolism, is the major cause of type I diabetes mellitus
Synonyms
1. island of Langerhans
2. island of pancreas
3. islet of Langerhans
References
1. Dorlands Medical Dictionary: MerckSource
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