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BRENDA support

Ontology explorer

BTO (BRENDA Tissue Ontology)
Download as: OBO OWL
Version 2021-10-23
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Details for tubercle
tubercletubercle
BTO (BRENDA Tissue Ontology) ID
BTO:0002173
BTO:0002173 is linked to 2 enzymes:
Definition
The adult male dorsal surface of Schistosoma is covered in small bosses called tubercles that provide purchase against the blood vessel wall when the worm is crawling up the mesenteric veins carrying the female in its ventral groove. Each tubercle has a thin, 2-3 micron, covering of the syncytial tegument. Enclosed entirely within the tegument cytoplasm of the tubercle are a series of spines, made of actin, which assist in gripping the blood vessel. The tegument is normally closely apposed to the underlying circular muscle layer, and separated from it only by an extracellular matrix of collagen fibres. The tubercle is the exception, where the tegument is lifted up by numerous extensions of parenchymal cells. The parenchymal cell bodies lie below the muscle layers and send out narrow extensions of cytoplasm which insinuate between the muscles to form the packing for the tubercle
References
1. University of York: R.A. Wilson
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