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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for Hedgehog signaling complex
Gene ontology ID
GO:0035301
Definition
A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila)
Synonyms
1. Hedgehog signalling complex
2. HSC
References
1. PMID 10825151
2. PMID 15057936
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