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Gene ontology
Version 2014-12-22
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Details for SMN complex
Gene ontology ID
GO:0032797
Definition
A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus
Comment
Note that a larger complex containing Sm proteins and other subunits is also sometimes referred to as the 'SMN complex'. The larger complex is represented by 'SMN-Sm protein complex ; GO:0034719'.
Synonyms
1. SMN core complex
2. survival motor neuron complex
References
1. PMID 16434402
2. PMID 17023415
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