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Gene ontology
Version 2014-12-22
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Details for epsilon DNA polymerase complex
Gene ontology ID
GO:0008622
Definition
A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair
Synonyms
1. DNA polymerase epsilon complex
References
1. PMID 15814431
2. PMID 9745046
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