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Gene ontology
Version 2014-12-22
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Details for thiazole synthase activity
2.8.1.10
Gene ontology ID
GO:1990107
Definition
Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O
Comment
H2S can provide the sulfur in vitro. Part of the pathway for thiamine biosynthesis.
Synonyms
1. 1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity
References
1. EC 2.8.1.10
2. GOC: cjk
3. PMID 22031445
4. RHEA: 26297
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