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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for NAD-dependent histone deacetylase activity (H3-K18 specific)
3.5.1.17
Gene ontology ID
GO:0097372
Definition
Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein
References
1. EC 3.5.1.17
2. GOC: sp
3. PMID 22722849
4. RHEA: 24548
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