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Gene ontology
Version 2014-12-22
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Details for 3',5'-cyclic-GMP phosphodiesterase activity
3.1.4.35
Gene ontology ID
GO:0047555
Definition
Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate
Synonyms
1. 3',5' cyclic-GMP phosphodiesterase activity
2. 3',5'-cyclic-GMP 5'-nucleotidohydrolase activity
3. cGMP phosphodiesterase activity
4. cGMP-PDE
5. cGMP-specific phosphodiesterase activity
6. cyclic 3',5'-GMP phosphodiesterase activity
7. cyclic GMP phosphodiesterase activity
8. cyclic guanosine 3',5'-monophosphate phosphodiesterase activity
9. cyclic guanosine 3',5'-phosphate phosphodiesterase activity
10. guanosine cyclic 3',5'-phosphate phosphodiesterase activity
References
1. EC 3.1.4.35
2. MetaCyc 35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN
3. Reactome: R-HSA-4086392 "PDE6 hydrolyses cGMP to GMP"
4. Reactome: R-HSA-418456 "cGMP is degraded by PDEs"
5. Reactome: R-HSA-74059 "PDE6 hydrolyses cGMP to GMP"
6. RHEA: 16957
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