1.11.1.12Gene ontology ID
GO:0047066
Definition
Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione
Synonyms
1. glutathione:lipid-hydroperoxide oxidoreductase activity
2. hydroperoxide glutathione peroxidase activity
3. peroxidation-inhibiting protein activity
4. peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)
5. PHGPX
6. phospholipid hydroperoxide glutathione peroxidase activity
References
1. EC 1.11.1.122. MetaCyc 1.11.1.12-RXN3. Reactome: R-HSA-9018868 "GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE"
4. Reactome: R-HSA-9018895 "GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE"
5. Reactome: R-HSA-9020271 "GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA"
6. Reactome: R-HSA-9020273 "GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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