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Gene ontology
Version 2014-12-22
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Details for mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
3.2.1.96
Gene ontology ID
GO:0033925
Definition
Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact
Synonyms
1. di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity
2. endo-beta-(1->4)-N-acetylglucosaminidase activity
3. endo-beta-acetylglucosaminidase activity
4. endo-beta-N-acetylglucosaminidase activity
5. endo-beta-N-acetylglucosaminidase D activity
6. endo-beta-N-acetylglucosaminidase F activity
7. endo-beta-N-acetylglucosaminidase H activity
8. endo-beta-N-acetylglucosaminidase L activity
9. endo-N-acetyl-beta-D-glucosaminidase activity
10. endo-N-acetyl-beta-glucosaminidase activity
11. endoglycosidase H activity
12. endoglycosidase S activity
13. glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity
14. glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity
15. mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity
16. mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity
17. N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity
References
1. EC 3.2.1.96
2. MetaCyc 3.2.1.96-RXN
3. Reactome: R-HSA-8853379 "ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5)"
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