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Gene ontology
Version 2014-12-22
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Details for 5-oxoprolinase (ATP-hydrolyzing) activity
3.5.2.9
Gene ontology ID
GO:0017168
Definition
Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate
Synonyms
1. 5-OPase activity
2. 5-oxo-L-prolinase activity
3. 5-oxo-L-proline amidohydrolase (ATP-hydrolysing)
4. 5-oxoprolinase (ATP-hydrolysing)
5. 5-oxoprolinase activity
6. L-pyroglutamate hydrolase activity
7. oxoprolinase activity
8. pyroglutamase (ATP-hydrolysing)
9. pyroglutamase (ATP-hydrolyzing) activity
10. pyroglutamase activity
11. pyroglutamate hydrolase activity
12. pyroglutamic hydrolase activity
References
1. EC 3.5.2.9
2. RHEA: 10348
3. KEGG REACTION: R00251
4. MetaCyc 5-OXOPROLINASE-ATP-HYDROLYSING-RXN
5. Reactome: R-HSA-1247935 "OPLAH hydrolyses OPRO to L-Glu"
6. Reactome: R-HSA-5603208 "Defective OPLAH does not hydrolyse OPRO"
7. Wikipedia: 5-oxoprolinase (ATP-hydrolysing)
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
hydrolase activity is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides is a
5-oxoprolinase (ATP-hydrolyzing) activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
beta-alanyl-dopamine hydrolase activity is a
beta-alanyl-histamine hydrolase activity is a
coenzyme F390-A hydrolase activity is a
coenzyme F390-G hydrolase activity is a
deacetylase activity is a
deaminase activity is a
hydrolase activity, acting on acid anhydrides is a
hydrolase activity, acting on acid carbon-carbon bonds is a
hydrolase activity, acting on acid carbon-phosphorus bonds is a
hydrolase activity, acting on acid halide bonds is a
hydrolase activity, acting on acid phosphorus-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-sulfur bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity is a
3-(N-formyl)-formiminopyruvate hydrolase activity is a
3-formiminopyruvate hydrolase activity is a
aminohydroquinone monooxygenase activity is a
gamma-aminovinylacetate deaminase activity is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides is a
2,5-dioxopiperazine hydrolase activity is a
3,5-dichlorophenylcarboximide hydrolase activity is a
5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity is a
5-oxoprolinase (ATP-hydrolyzing) activity is a
6-aminohexanoate-cyclic-dimer hydrolase activity is a
allantoinase activity is a
barbiturase activity is a
beta-lactamase activity is a
carboxymethylhydantoinase activity is a
citrazinate hydrolase activity is a
creatininase activity is a
cyanuric acid amidohydrolase activity is a
dihydroorotase activity is a
dihydropyrimidinase activity is a
enamidase activity is a
epsilon-caprolactam lactamase activity is a
hydroxyisourate hydrolase activity is a
imidazolone hydrolase activity is a
imidazolonepropionase activity is a
L-lysine-lactamase activity is a
maleimide hydrolase activity is a
N-methylhydantoinase (ATP-hydrolyzing) activity is a
xanthine hydrolase activity is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles is a
hydroxydechloroatrazine ethylaminohydrolase activity is a
IAA-amino acid conjugate hydrolase activity is a
jasmonic acid hydrolase is a
jasmonyl-Ile conjugate hydrolase activity is a
N-acetyl-anhydromuramoyl-L-alanine amidase activity is a
N-isopropylammelide isopropylaminohydrolase activity is a
riboflavinase activity is a
thiaminase activity is a
trans-ACOHDA hydrolase activity is a
hydrolase activity, acting on carbon-sulfur bonds is a
hydrolase activity, acting on ester bonds is a
hydrolase activity, acting on ether bonds is a
hydrolase activity, acting on glycosyl bonds is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a