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Gene ontology
Version 2014-12-22
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Details for 1-phosphatidylinositol-4-phosphate 5-kinase activity
2.7.1.68
Gene ontology ID
GO:0016308
Definition
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+)
Synonyms
1. 1-phosphatidylinositol-4-phosphate kinase activity
2. 1-phosphatidylinositol-4-phosphate kinase, class IA
3. 1-phosphatidylinositol-4-phosphate kinase, class IB
4. ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity
5. diphosphoinositide kinase activity
6. phosphatidylinositol 4-phosphate kinase activity
7. phosphatidylinositol-4-phosphate 5-kinase activity
8. PIP kinase activity
9. PIP5K
10. PtdIns(4)P-5-kinase activity
11. type I PIP kinase activity
References
1. EC 2.7.1.68
2. RHEA: 14425
3. KEGG REACTION: R03469
4. MetaCyc 2.7.1.68-RXN
5. Reactome: R-HSA-1676082 "PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane"
6. Reactome: R-HSA-3772436 "DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2"
7. Reactome: R-HSA-8868066 "PIP5K1C phosphorylates PI(4)P to PI(4,5)P2"
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