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Gene ontology
Version 2014-12-22
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Details for 4-hydroxy-2-oxoglutarate aldolase activity
4.1.3.16
Gene ontology ID
GO:0008700
Definition
Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate
Synonyms
1. 2-keto-4-hydroxybutyrate aldolase activity
2. 2-keto-4-hydroxyglutarate aldolase activity
3. 2-keto-4-hydroxyglutaric aldolase activity
4. 2-oxo-4-hydroxyglutarate aldolase activity
5. 2-oxo-4-hydroxyglutaric aldolase activity
6. 4-hydroxy-2-ketoglutarate aldolase activity
7. 4-hydroxy-2-ketoglutaric aldolase activity
8. 4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)
9. 4-hydroxy-2-oxoglutarate glyoxylate-lyase activity
10. DL-4-hydroxy-2-ketoglutarate aldolase activity
11. hydroxyketoglutarate aldolase activity
12. hydroxyketoglutaric aldolase activity
13. KHG-aldolase activity
References
1. EC 4.1.3.16
2. MetaCyc 4OH2OXOGLUTARALDOL-RXN
3. Reactome: R-HSA-6784423 "HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate"
4. RHEA: 18169
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