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Gene ontology
Version 2014-12-22
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Details for N-acetylglucosamine-6-sulfatase activity
3.1.6.14
Gene ontology ID
GO:0008449
Definition
Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate
Synonyms
1. 2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase activity
2. acetylglucosamine 6-sulfatase activity
3. chondroitinsulfatase
4. glucosamine-6-sulfatase activity
5. N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase activity
6. N-acetylglucosamine 6-sulfate sulfatase activity
7. N-acetylglucosamine-6-sulphatase activity
8. O,N-disulfate O-sulfohydrolase activity
References
1. EC 3.1.6.14
2. MetaCyc 3.1.6.14-RXN
3. Reactome: R-HSA-1638032 "N-acetylglucosamine 6-sulfatase (GNS) hydrolyses 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate"
4. Reactome: R-HSA-2263495 "Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
hydrolase activity is a
hydrolase activity, acting on ester bonds is a
sulfuric ester hydrolase activity is a
N-acetylglucosamine-6-sulfatase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
beta-alanyl-dopamine hydrolase activity is a
beta-alanyl-histamine hydrolase activity is a
coenzyme F390-A hydrolase activity is a
coenzyme F390-G hydrolase activity is a
deacetylase activity is a
deaminase activity is a
hydrolase activity, acting on acid anhydrides is a
hydrolase activity, acting on acid carbon-carbon bonds is a
hydrolase activity, acting on acid carbon-phosphorus bonds is a
hydrolase activity, acting on acid halide bonds is a
hydrolase activity, acting on acid phosphorus-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-nitrogen bonds is a
hydrolase activity, acting on acid sulfur-sulfur bonds is a
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds is a
hydrolase activity, acting on carbon-sulfur bonds is a
hydrolase activity, acting on ester bonds is a
aspartyl esterase activity is a
carboxylic ester hydrolase activity is a
DNA-3'-diphospho-5'-guanosine diphosphatase is a
enterochelin esterase activity is a
indole-3-acetyl-beta-1-D-glucose hydrolase activity is a
indole-3-acetyl-beta-4-D-glucose hydrolase activity is a
lipase activity is a
phosphoric ester hydrolase activity is a
sulfuric ester hydrolase activity is a
alkyl sulfatase activity is a
arylsulfatase activity is a
cellulose-polysulfatase activity is a
cerebroside-sulfatase activity is a
choline-sulfatase activity is a
chondro-4-sulfatase activity is a
chondro-6-sulfatase activity is a
D-lactate-2-sulfatase activity is a
disulfoglucosamine-6-sulfatase activity is a
endosulfan hemisulfate sulfatase activity is a
endosulfan sulfate hydrolase activity is a
glucuronate-2-sulfatase activity is a
glycosulfatase activity is a
iduronate-2-sulfatase activity is a
monomethyl-sulfatase activity is a
N-acetylgalactosamine-4-sulfatase activity is a
N-acetylgalactosamine-6-sulfatase activity is a
N-acetylglucosamine-6-sulfatase activity is a
N-sulfoglucosamine-3-sulfatase activity is a
steryl-sulfatase activity is a
thiolester hydrolase activity is a
versiconal hemiacetal acetate esterase activity is a
hydrolase activity, acting on ether bonds is a
hydrolase activity, acting on glycosyl bonds is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a