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Gene ontology
Version 2014-12-22
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Details for uroporphyrinogen-III synthase activity
4.2.1.75
Gene ontology ID
GO:0004852
Definition
Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III
Synonyms
1. hydroxymethylbilane hydro-lyase (cyclizing) activity
2. hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)
3. porphobilinogenase activity
4. URO-synthase activity
5. uroporphyrinogen III cosynthase activity
6. uroporphyrinogen isomerase activity
7. uroporphyrinogen-III cosynthase activity
8. uroporphyrinogen-III cosynthetase activity
References
1. EC 4.2.1.75
2. RHEA: 18965
3. KEGG REACTION: R03165
4. MetaCyc UROGENIIISYN-RXN
5. Reactome: R-HSA-189488 "UROS transforms HMB to URO3"
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