Ontology explorer

Gene ontology

Change ontology: Version 2014-12-22

Term or Synonym: use AND (NOT) or OR

Definition: use AND (NOT) or OR

Id:

restrict to BRENDA links:

Localization

Enzyme

Details for leucine-tRNA ligase activity

Gene ontology ID

GO:0004823

Definition

Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu)

Synonyms

1. L-leucine:tRNALeu ligase (AMP-forming)
2. leucine translase activity
3. leucine-tRNA synthetase activity
4. leucyl-transfer ribonucleate synthetase activity
5. leucyl-transfer ribonucleic acid synthetase activity
6. leucyl-transfer RNA synthetase activity
7. leucyl-tRNA synthetase activity

References

1. EC 6.1.1.4
2. RHEA: 11688
3. KEGG REACTION: R03657
4. MetaCyc LEUCINE--TRNA-LIGASE-RXN
5. Reactome: R-HSA-379974 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate"
6. Reactome: R-HSA-380200 "leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate"

Legend

is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

/

/

at least 1 tissue/ enzyme/ localization link in this branch

/

/

tissue/ enzyme/ localization link to BRENDA

Condensed Tree View

Gene ontology

molecular_function is a

is a

catalytic activity is a

is a

catalytic activity, acting on RNA is a

is a

catalytic activity, acting on a tRNA is a

is a

aminoacyl-tRNA ligase activity is a

is a

leucine-tRNA ligase activity is a

is a

Tree view

Gene ontology

biological_process is a

is a

cellular_component is a

is a

molecular_function is a

is a

is a

catalytic activity is a

is a

catalytic activity, acting on a protein is a

is a

catalytic activity, acting on DNA is a

is a

catalytic activity, acting on RNA is a

is a

catalytic activity, acting on a rRNA is a

is a

catalytic activity, acting on a tRNA is a

is a

aminoacyl-tRNA hydrolase activity is a

is a

aminoacyl-tRNA ligase activity is a

is a

alanine-tRNA ligase activity is a

is a

arginine-tRNA ligase activity is a

is a

asparagine-tRNA ligase activity is a

is a

aspartate-tRNA ligase activity is a

is a

aspartate-tRNA(Asn) ligase activity is a

is a

cysteine-tRNA ligase activity is a

is a

glutamate-tRNA ligase activity is a

is a

glutamate-tRNA(Gln) ligase activity is a

is a

glutamine-tRNA ligase activity is a

is a

glycine-tRNA ligase activity is a

is a

histidine-tRNA ligase activity is a

is a

isoleucine-tRNA ligase activity is a

is a

leucine-tRNA ligase activity is a

is a

lysine-tRNA ligase activity is a

is a

lysine-tRNA(Pyl) ligase activity is a

is a

methionine-tRNA ligase activity is a

is a

phenylalanine-tRNA ligase activity is a

is a

phosphoserine-tRNA(Cys) ligase activity is a

is a

proline-tRNA ligase activity is a

is a

pyrrolysyl-tRNA synthetase activity is a

is a

selenocysteine-tRNA ligase activity is a

is a

selenomethionine-tRNA ligase activity is a

is a

serine-tRNA ligase activity is a

is a

threonine-tRNA ligase activity is a

is a

tryptophan-tRNA ligase activity is a

is a

tyrosine-tRNA ligase activity is a

is a

valine-tRNA ligase activity is a

is a

asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity is a

is a

CTP:3'-cytidine-tRNA cytidylyltransferase activity is a

is a

CTP:tRNA cytidylyltransferase activity is a

is a

glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity is a

is a

L-seryl-tRNASec selenium transferase activity is a

is a

phosphoseryl-selenocysteinyl-tRNA selenium transferase activity is a

is a

queuine tRNA-ribosyltransferase activity is a

is a

S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity is a

is a

Ser(Gly)-tRNA(Ala) hydrolase activity is a

is a

Ser-tRNA(Thr) hydrolase activity is a

is a

seryl-selenocysteinyl-tRNA kinase activity is a

is a

tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase is a

is a

tRNA 2'-phosphotransferase activity is a

is a

tRNA 2-selenouridine synthase activity is a

is a

tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity is a

is a

tRNA A64-2'-O-ribosylphosphate transferase activity is a

is a

tRNA cytidylyltransferase activity is a

is a

tRNA dimethylallyltransferase activity is a

is a

tRNA nucleotidyltransferase activity is a

is a

tRNA pseudouridine synthase activity is a

is a

tRNA threonylcarbamoyladenosine dehydratase is a

is a

tRNA(Ile)-lysidine synthase activity is a

is a

tRNA-4-demethylwyosine synthase activity is a

is a

tRNA-5-taurinomethyluridine 2-sulfurtransferase is a

is a

tRNA-uridine aminocarboxypropyltransferase activity is a

is a

RNA glycosylase activity is a

is a

RNA helicase activity is a

is a

RNA ligase activity is a

is a

RNA polymerase activity is a

is a

RNA topoisomerase activity is a

is a

RNA uridylyltransferase activity is a

is a

RNA-3'-phosphate cyclase activity is a

is a

rRNA pseudouridine synthase activity is a

is a

snRNA pseudouridine synthase activity is a

is a

template-free RNA nucleotidyltransferase is a

is a

tyrosyl-RNA phosphodiesterase activity is a

is a

cyclase activity is a

is a

hydrolase activity is a

is a

isomerase activity is a

is a

ligase activity is a

is a

lyase activity is a

is a

peptidoglycan muralytic activity is a

is a

transferase activity is a

is a

molecular transducer activity is a

is a

nutrient reservoir activity is a

is a

protein tag is a

is a

small molecule sensor activity is a

is a

structural molecule activity is a

is a

transcription regulator activity is a

is a

transporter activity is a

is a

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)