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Gene ontology
Version 2014-12-22
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Details for RNA-DNA hybrid ribonuclease activity
3.1.26.4
Gene ontology ID
GO:0004523
Definition
Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters
Comment
Note that the EC recommended name for this enzyme activity is 'calf thymus ribonuclease H', even though it is found in many species.
Synonyms
1. calf thymus ribonuclease H activity
2. endoribonuclease H
3. endoribonuclease H (calf thymus)
4. endoribonuclease0 H activity
5. hybrid nuclease activity
6. hybrid ribonuclease activity
7. hybridase (ribonuclease H)
8. hybridase activity
9. ribonuclease H activity
10. ribonuclease H1 activity
11. ribonuclease H2 activity
12. ribonuclease H3 activity
13. RNA*DNA hybrid ribonucleotidohydrolase activity
14. RNase H activity
15. RNase H1 activity
16. RNase H2 activity
17. RNase H3 activity
References
1. EC 3.1.26.4
2. MetaCyc 3.1.26.4-RXN
3. Reactome: R-HSA-164519 "RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex"
4. Reactome: R-HSA-164528 "RNase H-mediated cleavage of the template strand"
5. Reactome: R-HSA-173769 "RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers"
6. Reactome: R-HSA-182795 "RNase H-mediated degradation of the template strand"
7. Reactome: R-HSA-182859 "RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular metabolic process is a
cellular aromatic compound metabolic process is a
nucleobase-containing compound metabolic process is a
nucleic acid metabolic process is a
nucleic acid phosphodiester bond hydrolysis is a
nuclease activity part of
endonuclease activity is a
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters is a
endoribonuclease activity, producing 5'-phosphomonoesters is a
RNA-DNA hybrid ribonuclease activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
bioluminescence is a
cellular alcohol metabolic process is a
cellular aldehyde metabolic process is a
cellular alkane metabolic process is a
cellular alkene metabolic process is a
cellular alkyne metabolic process is a
cellular aromatic compound metabolic process is a
(+)-kotanin metabolic process is a
2,5-dihydroxypyridine metabolic process is a
3-(3-hydroxy)phenylpropionate metabolic process is a
3-methylquinoline metabolic process is a
5-methylcytosine metabolic process is a
aromatic amino acid family metabolic process is a
aromatic compound biosynthetic process is a
aromatic compound catabolic process is a
aromatic primary alcohol metabolic process is a
benzene-containing compound metabolic process is a
carbazole metabolic process is a
cocaine metabolic process is a
coniferin metabolic process is a
daunorubicin metabolic process is a
demethylkotanin metabolic process is a
dibenzo-p-dioxin metabolic process is a
dibenzofuran metabolic process is a
doxorubicin metabolic process is a
epothilone metabolic process is a
fluorene metabolic process is a
imidazole-containing compound metabolic process is a
indole-containing compound metabolic process is a
isoquinoline alkaloid metabolic process is a
kynurenic acid metabolic process is a
naphthalene-containing compound metabolic process is a
nicotinate metabolic process is a
nucleobase-containing compound metabolic process is a
GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process is a
nucleic acid metabolic process is a
DNA metabolic process is a
nucleic acid phosphodiester bond hydrolysis is a
nuclease activity part of
endonuclease activity is a
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters is a
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters is a
endoribonuclease activity, producing 5'-phosphomonoesters is a
3'-tRNA processing endoribonuclease activity is a
apurinic/apyrimidinic endoribonuclease activity is a
endoribonuclease activity, cleaving siRNA-paired mRNA is a
phosphodiesterase decapping endonuclease activity is a
ribonuclease III activity is a
ribonuclease IV activity is a
ribonuclease IX activity is a
ribonuclease M5 activity is a
ribonuclease P activity is a
ribonuclease P4 activity is a
ribonuclease [poly-(U)-specific] activity is a
RNA lariat debranching enzyme activity is a
RNA-DNA hybrid ribonuclease activity is a
endoribonuclease activity is a
exonuclease activity is a
oligonucleotidase activity is a
ribonuclease activity is a
RNA phosphodiester bond hydrolysis is a
viral DNA cleavage involved in viral genome maturation is a
RNA metabolic process is a
nucleobase-containing small molecule metabolic process is a
polynucleotide dephosphorylation is a
ommochrome metabolic process is a
orlandin metabolic process is a
phenanthrene metabolic process is a
phenol-containing compound metabolic process is a
phenylpropanoid metabolic process is a
picolinic acid metabolic process is a
pteridine-containing compound metabolic process is a
purine-containing compound metabolic process is a
pyridine metabolic process is a
pyridoxamine metabolic process is a
pyridoxine metabolic process is a
s-triazine compound metabolic process is a
sterigmatocystin metabolic process is a
stilbene metabolic process is a
tetrapyrrole metabolic process is a
thiamine diphosphate metabolic process is a
thiamine-containing compound metabolic process is a
thiazole metabolic process is a
verruculogen metabolic process is a
vibriobactin metabolic process is a
cellular biosynthetic process is a
cellular carbohydrate metabolic process is a
cellular catabolic process is a
cellular ketone body metabolic process is a
cellular ketone metabolic process is a
cellular lipid metabolic process is a
cellular macromolecule metabolic process is a
cellular metabolic compound salvage is a
cellular modified amino acid metabolic process is a
cellular nitrogen compound metabolic process is a
cellular organohalogen metabolic process is a
chemosynthesis is a
cofactor metabolic process is a
drug metabolic process is a
generation of precursor metabolites and energy is a
heterocycle metabolic process is a
hydroperoxide metabolic process is a
metabolite repair is a
mucilage metabolic process is a
one-carbon metabolic process is a
organic acid metabolic process is a
organometal metabolic process is a
phosphorus metabolic process is a
photosynthesis is a
prenylation is a
reactive oxygen species metabolic process is a
selenium compound metabolic process is a
sulfur compound metabolic process is a
toxin metabolic process is a
xenobiotic metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a