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Version 2014-12-22
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Details for nicotinate-nucleotide diphosphorylase (carboxylating) activity
2.4.2.19
Gene ontology ID
GO:0004514
Definition
Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate
Synonyms
1. NAD pyrophosphorylase activity
2. nicotinate mononucleotide pyrophosphorylase (carboxylating)
3. nicotinate-nucleotide pyrophosphorylase (carboxylating) activity
4. nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)
5. QAPRTase activity
6. quinolinate phosphoribosyltransferase (decarboxylating) activity
7. quinolinic acid phosphoribosyltransferase activity
8. quinolinic phosphoribosyltransferase activity
References
1. EC 2.4.2.19
2. RHEA: 12733
3. KEGG REACTION: R03348
4. MetaCyc QUINOPRIBOTRANS-RXN
5. Reactome: R-HSA-197268 "QPRT transfers PRIB to QUIN to form NAMN"
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