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Gene ontology
Version 2014-12-22
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Details for glutathione transferase activity
2.5.1.18
Gene ontology ID
GO:0004364
Definition
Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group
Synonyms
1. glutathione conjugation reaction
2. glutathione S-alkyl transferase activity
3. glutathione S-alkyltransferase activity
4. glutathione S-aralkyltransferase activity
5. glutathione S-aryltransferase activity
6. glutathione S-transferase activity
7. RX:glutathione R-transferase activity
8. S-(hydroxyalkyl)glutathione lyase activity
References
1. EC 2.5.1.18
2. MetaCyc GSHTRAN-RXN
3. Reactome: R-HSA-176054 "GST dimers conjugate GSH with cytosolic substrates"
4. Reactome: R-HSA-176059 "GST trimers transfer GS from GSH to luminal substrates"
5. Reactome: R-HSA-3301943 "GSTK1 dimer transfers GS from GSH to CDNB"
6. Reactome: R-HSA-5423653 "MGST trimers transfer GS from GSH to AFXBO and AFNBO"
7. Reactome: R-HSA-9026777 "GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1"
8. Reactome: R-HSA-9026780 "LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1"
9. Reactome: R-HSA-9026901 "GGT transfers GSH to 16S,17S-epoxy-DHA to form PCTR1"
10. Reactome: R-HSA-9026911 "LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
transferase activity is a
transferase activity, transferring alkyl or aryl (other than methyl) groups is a
glutathione transferase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
Atg8 ligase activity is a
CDP-alcohol phosphotransferase activity is a
glucanosyltransferase activity is a
Kdo transferase activity is a
mannosylphosphate transferase activity is a
molybdopterin molybdotransferase activity is a
transferase activity, transferring acyl groups is a
transferase activity, transferring aldehyde or ketonic groups is a
transferase activity, transferring alkyl or aryl (other than methyl) groups is a
2-(3-amino-3-carboxypropyl)histidine synthase activity is a
2-cis,6-cis-farnesyl pyrophosphate synthase activity is a
3-deoxy-7-phosphoheptulonate synthase activity is a
3-deoxy-8-phosphooctulonate synthase activity is a
3-phosphoshikimate 1-carboxyvinyltransferase activity is a
4-hydroxybenzoate geranyltransferase activity is a
6,7-dimethyl-8-ribityllumazine synthase activity is a
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity is a
7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase is a
adenosyl-fluoride synthase activity is a
adenosylmethionine cyclotransferase activity is a
ADP dimethylallyltransferase activity is a
agmatine aminopropyltransferase activity is a
alkylglycerone-phosphate synthase activity is a
all-trans-decaprenyl-diphosphate synthase activity is a
all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity is a
all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity is a
aminodeoxyfutalosine synthase activity is a
AMP dimethylallyltransferase activity is a
aspulvinone dimethylallyltransferase activity is a
ATP dimethylallyltransferase activity is a
beta-pyrazolylalanine synthase activity is a
cadaverine aminopropyltransferase activity is a
chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity is a
chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity is a
chlorophyllide-b:phytyl-diphosphate phytyltransferase activity is a
chrysanthemyl diphosphate synthase activity is a
cob(I)yrinic acid a,c-diamide adenosyltransferase activity is a
cystathionine gamma-synthase activity is a
cystathionine gamma-synthase activity (acts on O-phosphohomoserine) is a
cysteate synthase activity is a
deoxyhypusine synthase activity is a
dihydropteroate synthase activity is a
discadenine synthase activity is a
galactose-6-sulfurylase activity is a
geranylfarnesyl diphosphate synthase activity is a
geranylgeranylglycerol-phosphate geranylgeranyltransferase activity is a
glutathione transferase activity is a
heptaprenyl diphosphate synthase activity is a
hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity is a
hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity is a
homogentisate geranylgeranyl transferase activity is a
homogentisate solanyltransferase activity is a
homospermidine synthase (spermidine-specific) activity is a
homospermidine synthase activity is a
hydroxymethylbilane synthase activity is a
isonocardicin synthase activity is a
L-mimosine synthase activity is a
lavandulyl diphosphate synthase activity is a
methionine adenosyltransferase activity is a
N-acetylneuraminate synthase activity is a
N-acylneuraminate-9-phosphate synthase activity is a
N2-(2-carboxyethyl)arginine synthase activity is a
neryl-diphosphate:isopentenyl-diphosphate cistransferase activity is a
nicotianamine synthase activity is a
O-phosphoserine sulfhydrylase activity is a
phosphoglycerol geranylgeranyltransferase activity is a
prenyltransferase activity is a
riboflavin synthase activity is a
selenocystathione synthase activity is a
selenomethionine adenosyltransferase activity is a
spermidine synthase activity is a
spermine synthase activity is a
sym-norspermidine synthase activity is a
thermospermine synthase activity is a
thiamine pyridinylase activity is a
thiamine-phosphate diphosphorylase activity is a
trans-hexaprenyltranstransferase activity is a
trans-octaprenyltranstransferase activity is a
trans-pentaprenyltranstransferase activity is a
trihydroxypterocarpan dimethylallyltransferase activity is a
tryptophan dimethylallyltransferase activity is a
UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity is a
uracilylalanine synthase activity is a
Z-farnesyl diphosphate synthase activity is a
zeatin 9-aminocarboxyethyltransferase activity is a
[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity is a
transferase activity, transferring glycosyl groups is a
transferase activity, transferring nitrogenous groups is a
transferase activity, transferring one-carbon groups is a
transferase activity, transferring phosphorus-containing groups is a
transferase activity, transferring selenium-containing groups is a
transferase activity, transferring sulfur-containing groups is a
UDP-L-rhamnose synthase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a