Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate
1. EC 3.1.3.92. RHEA: 16689
3. KEGG REACTION: R00303
4. MetaCyc GLUCOSE-6-PHOSPHATASE-RXN5. Reactome: R-HSA-3262512 "G6PC3 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (ubiquitous)"
6. Reactome: R-HSA-3266566 "G6PC2 hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (islet)"
7. Reactome: R-HSA-3274540 "Defective G6PC does not hydrolyze glucose 6-phosphate"
8. Reactome: R-HSA-3282876 "Defective G6PC3 does not hydrolyze glucose 6-phosphate"
9. Reactome: R-HSA-71825 "G6PC hydrolyzes glucose 6-phosphate to form glucose and orthophosphate (liver)"