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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for L-iduronidase activity
3.2.1.76
Gene ontology ID
GO:0003940
Definition
Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate
Synonyms
1. alpha-L-iduronidase activity
2. glycosaminoglycan alpha-L-iduronohydrolase activity
References
1. EC 3.2.1.76
2. MetaCyc 3.2.1.76-RXN
3. Reactome: R-HSA-1678716 "IDUA hydrolyses Heparan sulfate chain(1)"
4. Reactome: R-HSA-1793186 "IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS"
5. Reactome: R-HSA-2090037 "IDUA hydrolyses Heparan sulfate chain(6)"
6. Reactome: R-HSA-2206299 "Defective IDUA does not hydrolyse Heparan sulfate chain(6)"
7. Reactome: R-HSA-9036037 "Defective IDUA does not hydrolyse Heparan sulfate chain(1)"
8. Reactome: R-HSA-9036041 "Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS"
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// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
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