3.5.4.16Gene ontology ID
GO:0003934
Definition
Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate
Synonyms
1. dihydroneopterin triphosphate synthase activity
2. GTP 7,8-8,9-dihydrolase activity
3. GTP 8-formylhydrolase activity
4. guanosine triphosphate 8-deformylase activity
5. guanosine triphosphate cyclohydrolase activity
References
1. EC 3.5.4.162. KEGG REACTION: R00424
3. MetaCyc GTP-CYCLOHYDRO-I-RXN4. Reactome: R-HSA-1474146 "GCH1 reduces GTP to dihydroneopterin triphosphate"
5. RHEA: 17473
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derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA