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Gene ontology
Version 2014-12-22
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Details for DNA topoisomerase type I (single strand cut, ATP-independent) activity
5.6.2.1
Gene ontology ID
GO:0003917
Definition
Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle
Comment
Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.
Synonyms
1. deoxyribonucleate topoisomerase
2. DNA topoisomerase I activity
3. nicking-closing enzyme activity
4. omega-protein activity
5. relaxing enzyme activity
6. swivelase activity
7. topoisomerase
8. type I DNA topoisomerase activity
9. type I topoisomerase activity
10. untwisting enzyme activity
References
1. PMID 8811192
2. EC 5.6.2.1
3. MetaCyc 5.99.1.2-RXN
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
binding is a
heterocyclic compound binding is a
nucleic acid binding is a
DNA binding is a
DNA topoisomerase activity
DNA topoisomerase type I (single strand cut, ATP-independent) activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
2-aminoethylphosphonate binding is a
acyl binding is a
alkene binding is a
amide binding is a
amine binding is a
antigen binding is a
calcium oxalate binding is a
carbohydrate binding is a
carbohydrate derivative binding is a
cargo receptor ligand activity is a
cellulosome binding is a
chromatin binding is a
cofactor binding is a
dinitrosyl-iron complex binding is a
drug binding is a
exogenous protein binding is a
extracellular matrix binding is a
fatty acid derivative binding is a
flavonoid binding is a
heterocyclic compound binding is a
camalexin binding is a
ectoine binding is a
histamine binding is a
hydroxyectoine binding is a
leptomycin B binding is a
nucleic acid binding is a
annealing activity is a
DNA binding is a
bent DNA binding is a
damaged DNA binding is a
DNA binding, bending is a
DNA clamp loader activity is a
DNA end binding is a
DNA secondary structure binding is a
DNA template activity is a
DNA topoisomerase activity
DNA topoisomerase type I (single strand cut, ATP-independent) activity is a
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity is a
DNA translocase activity
double-stranded DNA binding is a
flap-structured DNA binding is a
G-quadruplex DNA binding is a
histone-dependent DNA binding is a
recombination hotspot binding is a
sequence-specific DNA binding is a
single-stranded DNA binding is a
transcription regulatory region DNA binding is a
triplex DNA binding is a
DNA/RNA hybrid binding is a
regulatory region nucleic acid binding is a
RNA binding is a
nucleobase binding is a
nucleoside phosphate binding is a
proline binding is a
tetrapyrrole binding is a
vitamin E binding is a
hormone binding is a
hydroxyapatite binding is a
ice binding is a
ion binding is a
kinetochore binding is a
lipid binding is a
metal cluster binding is a
MgATP(2-) binding is a
microfibril binding is a
modified amino acid binding is a
molecular adaptor activity is a
molecular sequestering activity
neurotransmitter binding is a
nitric oxide binding is a
odorant binding is a
organic cyclic compound binding is a
pigment binding is a
poly(3-hydroxyalkanoate) binding is a
polyamine binding is a
protein binding is a
protein-containing complex binding is a
quaternary ammonium group binding is a
selenium binding is a
small molecule binding is a
sulfur compound binding is a
synthetic cannabinoid binding is a
tetrahydrofolyl-poly(glutamate) polymer binding is a
toxic substance binding is a
virion binding is a
catalytic activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a