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Gene ontology
Version 2014-12-22
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Details for N-acetylglucosaminylphosphatidylinositol deacetylase activity
3.5.1.89
Gene ontology ID
GO:0000225
Definition
Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane
Comment
Note that this function was formerly EC:3.1.1.69.
Synonyms
1. 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity
2. acetylglucosaminylphosphatidylinositol deacetylase activity
3. GlcNAc-PI de-N-acetylase activity
4. GlcNAc-PI deacetylase activity
5. N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity
6. N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity
References
1. EC 3.5.1.89
2. MetaCyc 3.1.1.69-RXN
3. Reactome: R-HSA-162857 "N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate"
4. RHEA: 11660
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