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Gene ontology
Version 2014-12-22
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Details for protein tyrosine kinase activity
2.7.10
Gene ontology ID
GO:0004713
Definition
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate
Synonyms
1. JAK
2. Janus kinase activity
3. protein-tyrosine kinase activity
References
1. EC 2.7.10
2. Reactome: R-HSA-112333 "SRC autophosphorylation is positively regulated by InlA-bound CDH1"
3. Reactome: R-HSA-114600 "Fyn/Lyn-mediated phosphorylation of FcR1 gamma"
4. Reactome: R-HSA-1168394 "STAT5 tyrosine phosphorylation"
5. Reactome: R-HSA-1169421 "Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers"
6. Reactome: R-HSA-1225952 "Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants"
7. Reactome: R-HSA-1225960 "Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants"
8. Reactome: R-HSA-1247844 "Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants"
9. Reactome: R-HSA-1248655 "Trans-autophosphorylation of EGFRvIII mutant dimers"
10. Reactome: R-HSA-1250195 "SHC1 phosphorylation by ERBB2 heterodimers"
11. Reactome: R-HSA-1250315 "Trans-autophosphorylation of ERBB4 homodimers"
12. Reactome: R-HSA-1250348 "Phosphorylation of SHC1 by ERBB4 homodimers"
13. Reactome: R-HSA-1251922 "PLCG1 phosphorylation by p-EGFR:p-ERBB2"
14. Reactome: R-HSA-1295540 "IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5"
15. Reactome: R-HSA-1295609 "SRC phosphorylates SPRY2 on Y55 and Y227"
16. Reactome: R-HSA-1307963 "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4"
17. Reactome: R-HSA-1433418 "Phosphorylation of JAK2"
18. Reactome: R-HSA-1433454 "Phosphorylation of GAB2 by SFKs"
19. Reactome: R-HSA-1433488 "Phosphorylation of SHP2 by SFKs"
20. Reactome: R-HSA-1433506 "Phosphorylation of APS"
21. Reactome: R-HSA-1433542 "Phosphorylation and activation of VAV1"
22. Reactome: R-HSA-1470009 "Phosphorylation of STATs"
23. Reactome: R-HSA-1524186 "Phosphorylation of PLCgamma by PDGFR"
24. Reactome: R-HSA-1671691 "PRLR-bound STAT5 is phosphorylated"
25. Reactome: R-HSA-170070 "Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes"
26. Reactome: R-HSA-170156 "Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes"
27. Reactome: R-HSA-170991 "SRC-1 autophosphorylates"
28. Reactome: R-HSA-171011 "Binding and activation of MAP Kinase"
29. Reactome: R-HSA-174164 "Phosphorylation of Cyclin A:Cdk2 at Tyr 15"
30. Reactome: R-HSA-177930 "GAB1 phosphorylation by EGFR kinase"
31. Reactome: R-HSA-177934 "EGFR autophosphorylation"
32. Reactome: R-HSA-177937 "Phosphorylation of EGFR by SRC kinase"
33. Reactome: R-HSA-182969 "Phosphorylation of CBL (EGFR:CBL)"
34. Reactome: R-HSA-183058 "Phosphorylation of CBL (EGFR:GRB2:CBL)"
35. Reactome: R-HSA-1839065 "Phosphorylation of cytosolic FGFR1 fusion dimers"
36. Reactome: R-HSA-1839067 "Phosphorylation of BCR moiety of BCR-FGFR1"
37. Reactome: R-HSA-1839098 "Activated FGFR1 mutants and fusions phosphorylate PLCG1"
38. Reactome: R-HSA-1839110 "p-BCR-p-FGFR1 phosphorylates GAB2"
39. Reactome: R-HSA-1839112 "Phosphorylation of STAT5 by cytosolic FGFR1 fusions"
40. Reactome: R-HSA-186786 "Autophosphorylation of PDGF beta receptors"
41. Reactome: R-HSA-1888198 "FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3"
42. Reactome: R-HSA-190326 "Autocatalytic phosphorylation of FGFR4"
43. Reactome: R-HSA-190385 "Autocatalytic phosphorylation of FGFR3b"
44. Reactome: R-HSA-190388 "Autocatalytic phosphorylation of FGFR3c"
45. Reactome: R-HSA-190408 "Autocatalytic phosphorylation of FGFR2b"
46. Reactome: R-HSA-190413 "Autocatalytic phosphorylation of FGFR2c"
47. Reactome: R-HSA-190427 "Autocatalytic phosphorylation of FGFR1b"
48. Reactome: R-HSA-190429 "Autocatalytic phosphorylation of FGFR1c"
49. Reactome: R-HSA-191062 "Autocatalytic phosphorylation of Klotho-bound FGFR1c"
50. Reactome: R-HSA-191636 "Phosphorylation of Cx43 by c-src"
51. Reactome: R-HSA-1963581 "Trans-autophosphorylation of p-Y877-ERBB2 heterodimers"
52. Reactome: R-HSA-1963582 "Trans-autophosphorylation of ERBB2 heterodimers"
53. Reactome: R-HSA-1963586 "SRC family kinases phosphorylate ERBB2"
54. Reactome: R-HSA-1982066 "Ligand-independent phosphorylation of overexpressed FGFR1"
55. Reactome: R-HSA-2012073 "Autocatalytic phosphorylation of FGFR3c P250R mutant"
56. Reactome: R-HSA-2012082 "Autocatalytic phosphorylation of FGFR3 cysteine mutants"
57. Reactome: R-HSA-2012087 "Autocatalytic phosphorylation of FGFR4 Y367C mutant"
58. Reactome: R-HSA-202165 "Phosphorylation of ITAM motifs in CD3 complexes"
59. Reactome: R-HSA-202168 "Phosphorylation of ZAP-70 by Lck"
60. Reactome: R-HSA-202174 "Activation of ZAP-70"
61. Reactome: R-HSA-202216 "Phosphorylation of SLP-76"
62. Reactome: R-HSA-202233 "Inactivation of Lck by Csk"
63. Reactome: R-HSA-202245 "Phosphorylation of TBSMs in LAT"
64. Reactome: R-HSA-202248 "Phosphorylation of PLC-gamma1"
65. Reactome: R-HSA-202291 "Activation of Lck"
66. Reactome: R-HSA-202307 "Change of PKC theta conformation"
67. Reactome: R-HSA-2023455 "Autocatalytic phosphorylation of FGFR1c P252X mutant dimers"
68. Reactome: R-HSA-2023460 "Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity"
69. Reactome: R-HSA-2029268 "Phosphorylation and activation of PLCG"
70. Reactome: R-HSA-2029449 "Phosphorylation of SYK by Src kinases"
71. Reactome: R-HSA-2029453 "Phosphorylation of VAV"
72. Reactome: R-HSA-2029459 "Sequestering and phosphorylation Fc gamma receptors in the lipid rafts"
73. Reactome: R-HSA-2029984 "Autocatalytic phosphorylation of FGFR2 ligand-independent mutants"
74. Reactome: R-HSA-2029989 "Autocatalytic phosphorylation of overexpressed FGFR2 variants"
75. Reactome: R-HSA-2033485 "Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity"
76. Reactome: R-HSA-2033486 "Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding"
77. Reactome: R-HSA-2033488 "Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding"
78. Reactome: R-HSA-2033490 "Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity"
79. Reactome: R-HSA-2038387 "Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants"
80. Reactome: R-HSA-2038944 "Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity"
81. Reactome: R-HSA-205289 "Autophosphorylation of KIT"
82. Reactome: R-HSA-210291 "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src"
83. Reactome: R-HSA-210872 "Trans-phosphorylation of Tie2"
84. Reactome: R-HSA-212710 "EGFR activates PLC-gamma1 by phosphorylation"
85. Reactome: R-HSA-2130194 "ABL phosphorylates WAVEs"
86. Reactome: R-HSA-2197698 "Phosphorylation of WASP/N-WASP"
87. Reactome: R-HSA-2201322 "TIRAP is phosphorylated by BTK"
88. Reactome: R-HSA-2395412 "Phosphorylation of SYK"
89. Reactome: R-HSA-2395439 "Phosphorylation of DAP12"
90. Reactome: R-HSA-2395801 "Phosphorylation of LAT by p-SYK"
91. Reactome: R-HSA-2396594 "Phosphorylation of SLP-76 by p-SYK"
92. Reactome: R-HSA-2404193 "IGF1R phosphorylates SHC1"
93. Reactome: R-HSA-2404199 "IGF1,2:IGF1R autophosphorylates"
94. Reactome: R-HSA-2424484 "Phosphorylation of BTK by p-SYK"
95. Reactome: R-HSA-2424486 "Phosphorylation and activation of VAV2/VAV3 by SYK"
96. Reactome: R-HSA-2424487 "Phosphorylation of PLC-gamma by p-BTK/p-SYK"
97. Reactome: R-HSA-2428926 "IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4"
98. Reactome: R-HSA-2454208 "Phosphorylation of beta and gamma subunits by LYN"
99. Reactome: R-HSA-2454239 "Phosphorylation of SYK"
100. Reactome: R-HSA-2586553 "JAK2 Phosphorylates LEPR"
101. Reactome: R-HSA-2586555 "JAK2 Autophosphorylates in Response to Leptin"
102. Reactome: R-HSA-2671742 "JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin"
103. Reactome: R-HSA-2671829 "JAK2 Phosphorylates STAT5 in Response to Leptin"
104. Reactome: R-HSA-2671850 "JAK2 Phosphoryates STAT3 in Response to Leptin"
105. Reactome: R-HSA-2730833 "Phosphorylation of TEC kinases by p-SYK"
106. Reactome: R-HSA-2730843 "Phosphorylation of LAT by p-SYK"
107. Reactome: R-HSA-2730851 "Phosphorylation of SLP-76 by p-SYK"
108. Reactome: R-HSA-2730858 "Autophosphorylation of BTK/ITK"
109. Reactome: R-HSA-2730860 "Phosphorylation of GAB2 by SYK/FYN"
110. Reactome: R-HSA-2730862 "Autophosphorylation of LYN kinase"
111. Reactome: R-HSA-2730882 "Phosphorylation of PKC-theta"
112. Reactome: R-HSA-2730884 "Phosphorylation of NTAL by p-SYK/Lyn"
113. Reactome: R-HSA-2730886 "Phosphorylation of SHC by SYK kinase"
114. Reactome: R-HSA-2730888 "Phosphorylation of PLC-gamma"
115. Reactome: R-HSA-3215391 "PRMT5 is tyrosine phosphorylated by JAK2 V617F"
116. Reactome: R-HSA-354073 "Autophosphorylation of PTK2 at Y397"
117. Reactome: R-HSA-354124 "Phosphorylation of pPTK2 by SRC"
118. Reactome: R-HSA-372693 "Phosphorylation of BCAR1 by SRC-PTK2 complex"
119. Reactome: R-HSA-373747 "Phosphorylation of nephrin by FYN"
120. Reactome: R-HSA-373750 "SEMA4D interacts with Plexin-B1:ErbB2"
121. Reactome: R-HSA-374701 "Phosphorylation of DCC by Fyn"
122. Reactome: R-HSA-377640 "Autophosphorylation of SRC"
123. Reactome: R-HSA-380780 "Activation of Src"
124. Reactome: R-HSA-388831 "Phosphorylation of CD28"
125. Reactome: R-HSA-388833 "Phosphorylation of CTLA-4"
126. Reactome: R-HSA-389083 "Autophosphorylation of PDGF alpha receptors"
127. Reactome: R-HSA-389086 "Autophosphorylation of PDGF alpha/beta receptors"
128. Reactome: R-HSA-389354 "Activation of Vav1"
129. Reactome: R-HSA-389762 "Phosphorylation of PD-1"
130. Reactome: R-HSA-391156 "Phosphorylation of ITIM motif in SIRP alpha"
131. Reactome: R-HSA-391865 "Recruitment of FAK to NCAM1:Fyn in lipid rafts"
132. Reactome: R-HSA-391866 "Phosphorylation of FAK by Src kinase"
133. Reactome: R-HSA-391871 "Autophosphorylation of NCAM1 bound Fyn"
134. Reactome: R-HSA-3928578 "EPH receptors autophosphorylate"
135. Reactome: R-HSA-3928580 "SFKs phosphorylate EFNBs"
136. Reactome: R-HSA-3928583 "FYN phosphorylates NMDAR2B"
137. Reactome: R-HSA-3928594 "SFKs phosphorylate GIT1"
138. Reactome: R-HSA-3928604 "SFKs phosphorylate VAV2,3"
139. Reactome: R-HSA-3928610 "PTK2 autophosphorylates at Y397"
140. Reactome: R-HSA-3928627 "EPHB phosphorylates TIAM1"
141. Reactome: R-HSA-3928648 "SFKs phosphorylate NGEF"
142. Reactome: R-HSA-399934 "Phosphorylation of Plexin-A"
143. Reactome: R-HSA-399946 "Recruitment and activation of Cdk5"
144. Reactome: R-HSA-399947 "Tyrosine phosphorylation of CRMPs by Fes"
145. Reactome: R-HSA-4093332 "p-EPHB phosphorylates SDC2"
146. Reactome: R-HSA-418163 "Activated Src activates ERK"
147. Reactome: R-HSA-418859 "Phosphorylation of Unc5C"
148. Reactome: R-HSA-418872 "Phosphorylation of FADK1"
149. Reactome: R-HSA-419646 "SEMA4D interacts with Plexin-B1:Met"
150. Reactome: R-HSA-428888 "Phosphorylation of ROBO1 by ABL kinase"
151. Reactome: R-HSA-429441 "SYK activation by SRC"
152. Reactome: R-HSA-429449 "Syk activation leads to SLP-76 activation"
153. Reactome: R-HSA-432129 "FGR binds and phosphorylates LRP8"
154. Reactome: R-HSA-434836 "Syk/Lck phosphorylate LAT"
155. Reactome: R-HSA-4420117 "VEGFR2 autophosphorylates"
156. Reactome: R-HSA-4420121 "SFKs phosphorylate PLCG1"
157. Reactome: R-HSA-4420128 "SRC-1 phosphorylates SHB"
158. Reactome: R-HSA-4420206 "Phosphorylation of SRC-1"
159. Reactome: R-HSA-443817 "Phosphorylation of L1 by EPHB2"
160. Reactome: R-HSA-445076 "Phosphorylation of Y1229 in L1"
161. Reactome: R-HSA-445084 "Phosphorylation of L1 by SRC"
162. Reactome: R-HSA-445085 "Phosphorylation of VAV2"
163. Reactome: R-HSA-445091 "Phosphorylation of Neurofascin"
164. Reactome: R-HSA-451942 "Within the IL-2R complex JAK3 phosphorylates JAK1"
165. Reactome: R-HSA-452097 "Recruited STAT5 is phosphorylated"
166. Reactome: R-HSA-452100 "SHC1 bound to IL2 receptor is phosphorylated"
167. Reactome: R-HSA-452122 "JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB"
168. Reactome: R-HSA-508282 "SYK is a substrate for JAK1"
169. Reactome: R-HSA-5218640 "SRC-1 phosphorylates p-Y397-PTK2"
170. Reactome: R-HSA-5218642 "PTK2 autophosphorylates"
171. Reactome: R-HSA-5218806 "FYN autophosphorylates"
172. Reactome: R-HSA-5218809 "PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118"
173. Reactome: R-HSA-5218812 "FYN phosphorylates PAK2"
174. Reactome: R-HSA-5218820 "Src kinases phosphorylate VAV"
175. Reactome: R-HSA-5218828 "PTK2/SRC-1 phosphorylates BCAR1"
176. Reactome: R-HSA-5218830 "SRC-1 phosphorylates PTK2-beta"
177. Reactome: R-HSA-5218851 "p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407"
178. Reactome: R-HSA-5357429 "AXL autophosphorylates on Y772 and Y814"
179. Reactome: R-HSA-5607745 "1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG"
180. Reactome: R-HSA-5607750 "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan"
181. Reactome: R-HSA-5621355 "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG"
182. Reactome: R-HSA-5621363 "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2"
183. Reactome: R-HSA-5621370 "SYK autophosphorylates"
184. Reactome: R-HSA-5624486 "SFKs phosphorylates RAF1 on Y340,Y341"
185. Reactome: R-HSA-5637795 "Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant"
186. Reactome: R-HSA-5637796 "Phosphorylation of SHC1 by p-5Y-EGFRvIII"
187. Reactome: R-HSA-5654147 "Activated FGFR2 phosphorylates PLCG1"
188. Reactome: R-HSA-5654149 "Activated FGFR1 phosphorylates PLCG1"
189. Reactome: R-HSA-5654151 "Activated FGFR4 phosphorylates PLCG1"
190. Reactome: R-HSA-5654222 "Activated FGFR3 phosphorylates PLCG1"
191. Reactome: R-HSA-5654397 "Activated FGFR2 phosphorylates FRS2"
192. Reactome: R-HSA-5654407 "Activated FGFR2 phosphorylates SHC1"
193. Reactome: R-HSA-5654408 "Activated FGFR3 phosphorylates FRS2"
194. Reactome: R-HSA-5654418 "Activated FGFR4 phosphorylates FRS2"
195. Reactome: R-HSA-5654428 "Activated FGFR4 phosphorylates SHC1"
196. Reactome: R-HSA-5654545 "Ligand-independent phosphorylation of overexpressed FGFR1c"
197. Reactome: R-HSA-5654575 "Activated FGFR1 phosphorylates FRS2"
198. Reactome: R-HSA-5654578 "Activated FGFR1 phosphorylates FRS3"
199. Reactome: R-HSA-5654582 "Activated FGFR1 phosphorylates SHC1"
200. Reactome: R-HSA-5654587 "Activated FGFR1:p-FRS phosphorylates PPTN11"
201. Reactome: R-HSA-5654605 "Activated FGFR2 phosphorylates FRS3"
202. Reactome: R-HSA-5654607 "Activated FGFR2 phosphorylates PPTN11"
203. Reactome: R-HSA-5654628 "Activated FGFR3 phosphorylates FRS3"
204. Reactome: R-HSA-5654631 "Activated FGFR3 phosphorylates PPTN11"
205. Reactome: R-HSA-5654634 "Activated FGFR3 phosphorylates SHC1"
206. Reactome: R-HSA-5654653 "Activated FGFR4 phosphorylates FRS3"
207. Reactome: R-HSA-5654655 "Activated FGFR4 phosphorylates PPTN11"
208. Reactome: R-HSA-5655243 "Activated FGFR3 mutants phosphorylate PLCG1"
209. Reactome: R-HSA-5655268 "Activated FGFR2 mutants phosphorylate FRS2"
210. Reactome: R-HSA-5655270 "Activated FGFR3 mutants phosphorylate FRS2"
211. Reactome: R-HSA-5655278 "Activated FGFR1 mutants phosphorylate FRS2"
212. Reactome: R-HSA-5655284 "Activated FGFR4 mutants phosphorylate FRS2"
213. Reactome: R-HSA-5655301 "Activated FGFR2 mutants phosphorylate PLCG1"
214. Reactome: R-HSA-5655341 "Activated FGFR4 mutants phosphorylate PLCG1"
215. Reactome: R-HSA-5683930 "WICH phosphorylates H2AFX on Y142"
216. Reactome: R-HSA-5686587 "ABL1 phosphorylates RAD52"
217. Reactome: R-HSA-5690702 "LYN phosphorylates CD22"
218. Reactome: R-HSA-6784006 "STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2"
219. Reactome: R-HSA-6784319 "JAK1,TYK2 phosphorylate JAK1,TYK2"
220. Reactome: R-HSA-6790087 "HVEM induses BTLA phosphorylation"
221. Reactome: R-HSA-6806974 "MET dimers autophosphorylate"
222. Reactome: R-HSA-68954 "Mcm2-7 is phosphorylated by DDK"
223. Reactome: R-HSA-69195 "Phosphorylation of Cyclin E:CDK2 complexes by WEE1"
224. Reactome: R-HSA-873918 "Transphosphorylation of JAK1"
225. Reactome: R-HSA-873919 "Phosphorylation of JAK2"
226. Reactome: R-HSA-873922 "Phosphorylation of STAT1 by JAK kinases"
227. Reactome: R-HSA-873924 "Phosphorylation of IFNGR1 by JAK kinases"
228. Reactome: R-HSA-879907 "Tyrosine kinases phosphorylate the receptor"
229. Reactome: R-HSA-879909 "Activation of STAT5a/b by JAK2"
230. Reactome: R-HSA-879925 "SHC1 bound to the common beta chain becomes tyrosine phosphorylated"
231. Reactome: R-HSA-8847977 "FRK phosphorylates PTEN"
232. Reactome: R-HSA-8848005 "ERBB2 promotes PTK6 autophosphorylation"
233. Reactome: R-HSA-8848077 "PTK6 phosphorylates STAP2"
234. Reactome: R-HSA-8848124 "PTK6 phosphorylates STAT3"
235. Reactome: R-HSA-8848436 "PTK6 phosphorylates CDKN1B"
236. Reactome: R-HSA-8848606 "PTK6 phosphorylates PXN"
237. Reactome: R-HSA-8848726 "PTK6 phosphorylates BCAR1"
238. Reactome: R-HSA-8848758 "PTK6 phosphorylates AKT1"
239. Reactome: R-HSA-8848776 "PTK6 phosphorylates DOK1"
240. Reactome: R-HSA-8848818 "PTK6 phosphorylates CBL"
241. Reactome: R-HSA-8848873 "PTK6 phosphorylates ARAP1"
242. Reactome: R-HSA-8848975 "PTK6 phosphorylates KHDRBS1"
243. Reactome: R-HSA-8849032 "PTK6 phosphorylates KHDRBS2"
244. Reactome: R-HSA-8849042 "PTK6 phosphorylates KHDRBS3"
245. Reactome: R-HSA-8849068 "PTK6 phosphorylates ARHGAP35"
246. Reactome: R-HSA-8849102 "SRMS phosphorylates PTK6"
247. Reactome: R-HSA-8849463 "PTK6 phosphorylates SFPQ"
248. Reactome: R-HSA-8851890 "MET phosphorylates SHC1-2"
249. Reactome: R-HSA-8851933 "MET phosphorylates GAB1"
250. Reactome: R-HSA-8853309 "Autocatalytic phosphorylation of FGFR3 fusions"
251. Reactome: R-HSA-8853313 "FGFR2 fusions autophosphorylate"
252. Reactome: R-HSA-8853315 "Activated FGFR3 fusions phosphorylate FRS2"
253. Reactome: R-HSA-8853325 "Plasma membrane FGFR1 fusions autophosphorylate"
254. Reactome: R-HSA-8855237 "FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1"
255. Reactome: R-HSA-8857555 "EGFR phosphorylates GPNMB"
256. Reactome: R-HSA-8857577 "LINC01139 facilitates PTK6 autophosphorylation"
257. Reactome: R-HSA-8857583 "LINC01139 promotes phosphorylation of HIF1A by PTK6"
258. Reactome: R-HSA-8857925 "Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307"
259. Reactome: R-HSA-8867041 "EGFR phosphorylates EPS15"
260. Reactome: R-HSA-8874078 "PTK2 autophosphorylates"
261. Reactome: R-HSA-8874080 "SRC phosphorylates PTK2"
262. Reactome: R-HSA-8874082 "MET phosphorylates PTK2"
263. Reactome: R-HSA-8875451 "MET phosphorylates CBL"
264. Reactome: R-HSA-8875817 "MET phosphorylates STAT3"
265. Reactome: R-HSA-8876230 "InlB:MET dimer trans-autophophorylates"
266. Reactome: R-HSA-8876246 "InlB-activated MET phosphorylates CBL"
267. Reactome: R-HSA-8876948 "SRC phosphorylates InlA-bound CDH1 and CTNNB1"
268. Reactome: R-HSA-8937728 "SRC phosphorylates RUNX1"
269. Reactome: R-HSA-8937807 "SRC phosphorylates RUNX3"
270. Reactome: R-HSA-8937844 "SRC,YES1 phosphorylate YAP1"
271. Reactome: R-HSA-8942607 "Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes"
272. Reactome: R-HSA-8948143 "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18"
273. Reactome: R-HSA-8956659 "ABL1 phosphorylates YAP1"
274. Reactome: R-HSA-8964242 "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC"
275. Reactome: R-HSA-8964252 "G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC"
276. Reactome: R-HSA-8983872 "JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4"
277. Reactome: R-HSA-9006323 "Phospho-JAK2 phosphorylates EPOR"
278. Reactome: R-HSA-9006332 "JAK2 transphosphorylates and is activated in response to Erythropoietin"
279. Reactome: R-HSA-9011241 "SRC phosphorylates ROBO3.1 in response to NTN1"
280. Reactome: R-HSA-9012650 "JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2"
281. Reactome: R-HSA-9018572 "EGFR phosphorylates NOTCH3"
282. Reactome: R-HSA-9021609 "ESR-associated SRC autophosphorylates"
283. Reactome: R-HSA-9024726 "LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1"
284. Reactome: R-HSA-9026464 "BDNF-bound NTRK2 dimers trans-autophosphorylate"
285. Reactome: R-HSA-9026502 "NTF3-bound NTRK2 dimers trans-autophosphorylate"
286. Reactome: R-HSA-9026510 "NTF4-bound NTRK2 dimers trans-autophosphorylate"
287. Reactome: R-HSA-9026579 "NTRK2 phosphorylates PLCG1"
288. Reactome: R-HSA-9026890 "NTRK2 phosphorylates SHC1"
289. Reactome: R-HSA-9027272 "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2"
290. Reactome: R-HSA-9027273 "JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1"
291. Reactome: R-HSA-9027425 "LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2"
292. Reactome: R-HSA-9028728 "NTRK2 phosphorylates FRS2"
293. Reactome: R-HSA-9029151 "JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1"
294. Reactome: R-HSA-9029155 "JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1"
295. Reactome: R-HSA-9032426 "NTRK2 phosphorylates FRS3"
296. Reactome: R-HSA-9032532 "NTRK2-bound FYN autophosphorylates"
297. Reactome: R-HSA-9032601 "FYN-mediated phosphorylation of GRIN2B"
298. Reactome: R-HSA-9032854 "NTRK2 phosphorylates CDK5"
299. Reactome: R-HSA-9033284 "NTRK2 promotes TIAM1 phosphorylation"
300. Reactome: R-HSA-9034714 "NTRK3 dimers trans-autophosphorylate"
301. Reactome: R-HSA-9034814 "NTRK3 phosphorylates PLCG1"
302. Reactome: R-HSA-9034875 "NTRK3 phosphorylates SHC1"
303. Reactome: R-HSA-9037040 "SRC,FYN phosphorylate NTRK2"
304. Reactome: R-HSA-909718 "Formation of p-STAT1 homodimer"
305. Reactome: R-HSA-909726 "Phosphorylation of STAT1"
306. Reactome: R-HSA-909729 "Activation of JAK kinases"
307. Reactome: R-HSA-909730 "Phosphorylation of INFAR1 by TYK2"
308. Reactome: R-HSA-909732 "Phosphorylation of STAT2"
309. Reactome: R-HSA-912629 "CBL is tyrosine phosphorylated"
310. Reactome: R-HSA-9603420 "Activated NTRK3 promotes SRC autophosphorylation"
311. Reactome: R-HSA-9606159 "BTK autophosphorylates"
312. Reactome: R-HSA-9606162 "Phosphorylated BTK phosphorylates PLCG2"
313. Reactome: R-HSA-9606163 "p-SYK and LYN phosphorylate BTK"
314. Reactome: R-HSA-9612085 "SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs"
315. Reactome: R-HSA-9612996 "NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates"
316. Reactome: R-HSA-9613023 "NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates"
317. Reactome: R-HSA-9625487 "PTK2 autophosphorylates downstream of EGFR"
318. Reactome: R-HSA-982807 "JAK2 phosphorylation of GHR"
319. Reactome: R-HSA-983703 "p-6Y-SYK phosphorylates BLNK (SLP65)"
320. Reactome: R-HSA-983707 "SYK autophosphorylates at the activated BCR"
321. Reactome: R-HSA-983709 "LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B)"
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is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
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