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Gene ontology
Version 2014-12-22
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Details for oxoglutarate dehydrogenase (NAD+) activity
1.2.1
Gene ontology ID
GO:0034602
Definition
Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH
References
1. GOC: mah
2. EC 1.2.1
3. KEGG REACTION: R08549
4. MetaCyc 2OXOGLUTARATEDEH-RXN
5. Reactome: R-HSA-71037 "alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+"
6. Reactome: R-HSA-71401 "alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
metabolic process is a
oxidation-reduction process is a
oxidoreductase activity part of
oxidoreductase activity, acting on the aldehyde or oxo group of donors is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor is a
oxoglutarate dehydrogenase [NAD(P)+] activity is a
oxoglutarate dehydrogenase (NAD+) activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
adaptive thermogenesis is a
ATP metabolic process is a
biosynthetic process is a
catabolic process is a
collagen metabolic process is a
demethylation is a
glycosylation is a
hydrogen metabolic process is a
methylation is a
multi-organism metabolic process is a
NAD metabolic process is a
NADH metabolic process is a
NADP metabolic process is a
nitrogen compound metabolic process is a
organic substance metabolic process is a
oxidation-reduction process is a
iodide oxidation is a
oxidative deethylation is a
oxidoreductase activity part of
1,1,1-trichloroethane reductive dehalogenase activity is a
1,1,2-trichloroethene reductive dehalogenase activity is a
1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity is a
1,1-dichloroethane reductive dehalogenase activity is a
1,2-dichloroethene reductive dehalogenase activity is a
2,4-dichloroaniline reductive dehalogenase activity is a
2,4-dichlorophenoxyacetate dehalogenase activity is a
2,5-dichlorohydroquinone reductive dehalogenase activity is a
2-chloro-N-isopropylacetanilide reductive dehalogenase activity is a
2-octaprenylphenol hydroxylase activity is a
2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity is a
3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity is a
3,3',5-tribromobisphenol A reductive dehalogenase activity is a
3,3'-dibromobisphenol A reductive dehalogenase activity is a
3,8-divinyl protochlorophyllide a 8-vinyl reductase activity is a
3-monobromobisphenol A reductive dehalogenase activity is a
alpha-ketoacid dehydrogenase activity is a
arsenate reductase activity is a
chlorate reductase activity is a
chromate reductase activity is a
crotonyl-CoA reductase activity is a
delta1-piperideine-6-carboxylate dehydrogenase activity is a
dihydronicotinamide riboside quinone reductase activity is a
dihydropterin oxidase activity is a
dimethylarsinate reductase activity is a
dioxygenase activity is a
epoxyqueuosine reductase activity is a
fatty acid alpha-hydroxylase activity is a
geranylgeranyl reductase activity is a
glycyl-radical enzyme activating activity is a
heme-copper terminal oxidase activity is a
hydroxymethylbutenyl pyrophosphate reductase activity is a
malolactic enzyme activity is a
monooxygenase activity is a
NADPH-adrenodoxin reductase activity is a
NADPH:sulfur oxidoreductase activity is a
ortho-trichlorophenol reductive dehalogenase activity is a
oxidoreductase activity, acting on a heme group of donors is a
oxidoreductase activity, acting on a sulfur group of donors is a
oxidoreductase activity, acting on CH or CH2 groups is a
oxidoreductase activity, acting on CH-OH group of donors is a
oxidoreductase activity, acting on diphenols and related substances as donors is a
oxidoreductase activity, acting on halogen in donors is a
oxidoreductase activity, acting on hydrogen as donor is a
oxidoreductase activity, acting on iron-sulfur proteins as donors is a
oxidoreductase activity, acting on NAD(P)H is a
oxidoreductase activity, acting on other nitrogenous compounds as donors is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen is a
oxidoreductase activity, acting on peroxide as acceptor is a
oxidoreductase activity, acting on phosphorus or arsenic in donors is a
oxidoreductase activity, acting on reduced flavodoxin as donor is a
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen is a
oxidoreductase activity, acting on superoxide radicals as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors is a
1-pyrroline dehydrogenase activity is a
2,4,4-trimethylpentanal dehydrogenase activity is a
4,4-dimethyl-3-oxopentanal dehydrogenase activity is a
4-hydroxybutaraldehyde dehydrogenase activity is a
aldehyde dehydrogenase (FAD-independent) activity is a
aldehyde dehydrogenase (quinone) activity is a
alpha-keto amide reductase activity is a
alpha-keto ester reductase activity is a
carbon-monoxide dehydrogenase (acceptor) activity is a
carboxylate reductase activity is a
formaldehyde dismutase activity is a
formate dehydrogenase (coenzyme F420) activity is a
formylmethanofuran dehydrogenase activity is a
glyceraldehyde oxidoreductase activity is a
myrtenal dehydrogenase activity is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor is a
(R)-dehydropantoate dehydrogenase activity is a
1-hydroxy-2-naphthaldehyde dehydrogenase activity is a
1-naphthaldehyde dehydrogenase activity is a
2,5-dioxovalerate dehydrogenase (NAD+) activity is a
2,5-dioxovalerate dehydrogenase (NADP+) activity is a
2-oxobutyrate synthase activity is a
2-oxoisovalerate dehydrogenase (acylating) activity is a
3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity is a
3-aminopropanal dehydrogenase activity is a
3-chloroallyl aldehyde dehydrogenase activity is a
3-methylsalicylaldehyde dehydrogenase activity is a
4-formylbenzenesulfonate dehydrogenase activity is a
4-hydroxymuconic-semialdehyde dehydrogenase activity is a
4-methyl-2-oxopentanoate dehydrogenase activity is a
4-trimethylammoniobutyraldehyde dehydrogenase activity is a
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity is a
5-oxovalerate dehydrogenase activity is a
6-oxohexanoate dehydrogenase activity is a
abieta-7,13-dien-18-al dehydrogenase activity is a
acetaldehyde dehydrogenase (acetylating) activity is a
alcohol-forming fatty acyl-CoA reductase activity is a
aldehyde dehydrogenase [NAD(P)+] activity is a
aldehyde dehydrogenase (NAD+) activity is a
2-carboxybenzaldehyde dehydrogenase activity is a
2-naphthaldehyde dehydrogenase activity is a
2-oxoaldehyde dehydrogenase (NAD+) activity is a
4-hydroxybenzaldehyde dehydrogenase activity is a
4-hydroxymethylsalicyaldehyde dehydrogenase activity is a
4-hydroxyphenylacetaldehyde dehydrogenase activity is a
aminobutyraldehyde dehydrogenase activity is a
aryl-aldehyde dehydrogenase (NAD) activity is a
benzaldehyde dehydrogenase (NAD+) activity is a
betaine-aldehyde dehydrogenase activity is a
fluoroacetaldehyde dehydrogenase activity is a
formaldehyde dehydrogenase activity is a
gamma-guanidinobutyraldehyde dehydrogenase activity is a
glycolaldehyde dehydrogenase activity is a
lactaldehyde dehydrogenase activity is a
long-chain-aldehyde dehydrogenase activity is a
medium-chain-aldehyde dehydrogenase activity is a
phenylacetaldehyde dehydrogenase activity is a
salicylaldehyde dehydrogenase activity is a
aldehyde dehydrogenase (NADP+) activity is a
benzaldehyde dehydrogenase [NAD(P)+] activity is a
coniferyl-aldehyde dehydrogenase activity is a
aminomuconate-semialdehyde dehydrogenase activity is a
aspartate-semialdehyde dehydrogenase activity is a
bixin aldehyde dehydrogenase activity is a
butanal dehydrogenase activity is a
cinnamoyl-CoA reductase activity is a
cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity is a
citronellal dehydrogenase activity is a
delta1-pyrroline-5-carboxylate synthetase activity is a
erythrose-4-phosphate dehydrogenase activity is a
fatty aldehyde dehydrogenase activity is a
fatty-acyl-CoA reductase (alcohol-forming) activity is a
formate dehydrogenase (NAD+) activity is a
formate dehydrogenase (NADP+) activity is a
geranial dehydrogenase activity is a
glutamate-5-semialdehyde dehydrogenase activity is a
glutamyl-tRNA reductase activity is a
glutarate-semialdehyde dehydrogenase (NAD+) activity is a
glutarate-semialdehyde dehydrogenase (NADP+) activity is a
glyceraldehyde dehydrogenase (NADP) activity is a
glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity is a
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity is a
glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity is a
glyoxylate dehydrogenase (acylating) activity is a
hexadecanal dehydrogenase (acylating) activity is a
L-aminoadipate-semialdehyde dehydrogenase activity is a
long-chain-fatty-acyl-CoA reductase activity is a
malonate-semialdehyde dehydrogenase (acetylating) activity is a
malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity is a
malonate-semialdehyde dehydrogenase activity is a
methylmalonate-semialdehyde dehydrogenase (acylating) activity is a
mycothiol-dependent formaldehyde dehydrogenase activity is a
N-acetyl-gamma-aminoadipyl-phosphate reductase activity is a
N-acetyl-gamma-glutamyl-phosphate reductase activity is a
N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity is a
oxoglutarate dehydrogenase [NAD(P)+] activity is a
oxoglutarate dehydrogenase (NAD+) activity is a
oxoglutarate dehydrogenase (NADP+) activity is a
phenylglyoxylate dehydrogenase (acylating) activity is a
pyruvate dehydrogenase [NAD(P)+] activity is a
retinal dehydrogenase activity is a
sinapaldehyde:NAD(P)+ oxidoreductase activity is a
succinate-semialdehyde dehydrogenase [NAD(P)+] activity is a
succinylglutamate-semialdehyde dehydrogenase activity is a
sulfoacetaldehyde dehydrogenase activity is a
trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity is a
vanillin dehydrogenase activity is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor is a
pyruvate dehydrogenase activity is a
oxidoreductase activity, acting on the CH-CH group of donors is a
oxidoreductase activity, acting on the CH-NH group of donors is a
oxidoreductase activity, acting on the CH-NH2 group of donors is a
oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond is a
oxidoreductase activity, oxidizing metal ions is a
oxygen evolving activity is a
perchlorate reductase activity is a
phthalate dioxygenase reductase activity is a
pyrogallol hydroxytransferase activity is a
reduced coenzyme F420 dehydrogenase activity is a
reduced coenzyme F420 oxidase activity is a
reduced coenzyme F420:quinone oxidoreductase activity is a
selenate reductase activity is a
sphingosine hydroxylase activity is a
steroid dehydrogenase activity is a
sulfur oxygenase reductase activity is a
sulfur reductase activity is a
tetrachloroethene reductive dehalogenase activity is a
tetrahydrothiophene 1-oxide reductase activity is a
thyroxine 5'-deiodinase activity is a
thyroxine 5-deiodinase activity is a
trimethylarsine oxidase activity is a
tyramine-beta hydroxylase activity is a
uracil oxygenase activity is a
vinyl chloride reductive dehalogenase activity is a
violaxanthin de-epoxidase activity is a
thioredoxin reduction is a
pigment metabolic process is a
primary metabolic process is a
respiratory burst is a
secondary metabolic process is a
small molecule metabolic process is a
tartrate metabolic process is a
tyrocidine metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a