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Gene ontology
Version 2014-12-22
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Details for lyase activity
4.-.-.-, 4
Gene ontology ID
GO:0016829
Definition
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring
Comment
Note that enzymes of class EC:4.99.-.- should also be annotated to this term.
Synonyms
1. other lyase activity
References
1. EC 4.-.-.-
2. ISBN 0198547684
3. EC 4
4. Reactome: R-HSA-5696408 "PHYKPL tetramer hydrolyses 5PHL"
5. Reactome: R-HSA-6782895 "TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe)"
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