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Gene ontology
Version 2014-12-22
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Details for delta14-sterol reductase activity
1.3.1.70
Gene ontology ID
GO:0050613
Definition
Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol
Comment
Note that zymosterol is cholesta-8,24-dien-3-ol.
Synonyms
1. 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity
2. C-14 sterol reductase activity
3. D14-sterol reductase activity
4. sterol C-14 reductase activity
5. sterol C14-reductase activity
References
1. EC 1.3.1.70
2. MetaCyc 1.3.1.70-RXN
3. Reactome: R-HSA-194674 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR]"
4. Reactome: R-HSA-194698 "4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2]"
5. RHEA: 18561
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is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
metabolic process is a
oxidation-reduction process is a
oxidoreductase activity part of
oxidoreductase activity, acting on the CH-CH group of donors is a
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor is a
delta14-sterol reductase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
adaptive thermogenesis is a
ATP metabolic process is a
biosynthetic process is a
catabolic process is a
collagen metabolic process is a
demethylation is a
glycosylation is a
hydrogen metabolic process is a
methylation is a
multi-organism metabolic process is a
NAD metabolic process is a
NADH metabolic process is a
NADP metabolic process is a
nitrogen compound metabolic process is a
organic substance metabolic process is a
oxidation-reduction process is a
iodide oxidation is a
oxidative deethylation is a
oxidoreductase activity part of
1,1,1-trichloroethane reductive dehalogenase activity is a
1,1,2-trichloroethene reductive dehalogenase activity is a
1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity is a
1,1-dichloroethane reductive dehalogenase activity is a
1,2-dichloroethene reductive dehalogenase activity is a
2,4-dichloroaniline reductive dehalogenase activity is a
2,4-dichlorophenoxyacetate dehalogenase activity is a
2,5-dichlorohydroquinone reductive dehalogenase activity is a
2-chloro-N-isopropylacetanilide reductive dehalogenase activity is a
2-octaprenylphenol hydroxylase activity is a
2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity is a
3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity is a
3,3',5-tribromobisphenol A reductive dehalogenase activity is a
3,3'-dibromobisphenol A reductive dehalogenase activity is a
3,8-divinyl protochlorophyllide a 8-vinyl reductase activity is a
3-monobromobisphenol A reductive dehalogenase activity is a
alpha-ketoacid dehydrogenase activity is a
arsenate reductase activity is a
chlorate reductase activity is a
chromate reductase activity is a
crotonyl-CoA reductase activity is a
delta1-piperideine-6-carboxylate dehydrogenase activity is a
dihydronicotinamide riboside quinone reductase activity is a
dihydropterin oxidase activity is a
dimethylarsinate reductase activity is a
dioxygenase activity is a
epoxyqueuosine reductase activity is a
fatty acid alpha-hydroxylase activity is a
geranylgeranyl reductase activity is a
glycyl-radical enzyme activating activity is a
heme-copper terminal oxidase activity is a
hydroxymethylbutenyl pyrophosphate reductase activity is a
malolactic enzyme activity is a
monooxygenase activity is a
NADPH-adrenodoxin reductase activity is a
NADPH:sulfur oxidoreductase activity is a
ortho-trichlorophenol reductive dehalogenase activity is a
oxidoreductase activity, acting on a heme group of donors is a
oxidoreductase activity, acting on a sulfur group of donors is a
oxidoreductase activity, acting on CH or CH2 groups is a
oxidoreductase activity, acting on CH-OH group of donors is a
oxidoreductase activity, acting on diphenols and related substances as donors is a
oxidoreductase activity, acting on halogen in donors is a
oxidoreductase activity, acting on hydrogen as donor is a
oxidoreductase activity, acting on iron-sulfur proteins as donors is a
oxidoreductase activity, acting on NAD(P)H is a
oxidoreductase activity, acting on other nitrogenous compounds as donors is a
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen is a
oxidoreductase activity, acting on peroxide as acceptor is a
oxidoreductase activity, acting on phosphorus or arsenic in donors is a
oxidoreductase activity, acting on reduced flavodoxin as donor is a
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen is a
oxidoreductase activity, acting on superoxide radicals as acceptor is a
oxidoreductase activity, acting on the aldehyde or oxo group of donors is a
oxidoreductase activity, acting on the CH-CH group of donors is a
(R)-benzylsuccinyl-CoA dehydrogenase activity is a
1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity is a
1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity is a
1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity is a
2,4,4-trimethylpentanoyl-CoA dehydrogenase activity is a
2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity is a
2-furoyl-CoA dehydrogenase activity is a
2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity is a
2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity is a
2-methylhexanoyl-CoA dehydrogenase activity is a
24-methyldesmosterol reductase activity is a
4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity is a
4-methyloctanoyl-CoA dehydrogenase activity is a
acyl-CoA dehydrogenase activity is a
carvone reductase activity is a
cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity is a
cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity is a
coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity is a
coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity is a
coenzyme F420-dependent 2,4-dinitrophenol reductase activity is a
coproporphyrinogen dehydrogenase activity is a
cyclohexanone dehydrogenase activity is a
isoquinoline 1-oxidoreductase activity is a
naphthyl-2-methyl-succinyl-CoA dehydrogenase activity is a
oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor is a
oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor is a
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor is a
(+)-pulegone reductase, (+)-isomenthone as substrate, activity is a
(+)-pulegone reductase, (-)-menthone as substrate, activity is a
(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity is a
1,2-dihydrovomilenine reductase activity is a
1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity is a
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity is a
1-penten-3-one reductase activity is a
11-hydroxythromboxane B2 dehydrogenase activity is a
12-hydroxyheptadecatrienoic acid synthase activity is a
12-oxophytodienoate reductase activity is a
15-oxoprostaglandin 13-oxidase activity is a
2'-hydroxydaidzein reductase activity is a
2'-hydroxyisoflavone reductase activity is a
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity is a
2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity is a
2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity is a
2,4-dichlorobenzoyl-CoA reductase activity is a
2,4-dienoyl-CoA reductase (NADPH) activity is a
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity is a
2-alkenal reductase [NAD(P)+] activity is a
2-butyl-4-hydroxy-5-methyl-3(2H)-furanoneoxidoreductase activity is a
2-chloroacrylate reductase activity is a
2-coumarate reductase activity is a
2-enoate reductase activity is a
2-hexadecenal reductase activity is a
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity is a
2-methyl-branched-chain-enoyl-CoA reductase activity is a
22-alpha-hydroxy-campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity is a
24-epi-campsterol desaturase activity is a
3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity is a
3-methyleneoxindole reductase activity is a
4-hydroxy-5-methyl-2-propyl-3(2H)-furanone oxidoreductase activity is a
4-hydroxy-tetrahydrodipicolinate reductase is a
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity is a
7-dehydrocholesterol reductase activity is a
acrolein reductase activity is a
acryloyl-CoA reductase (NADP+) activity is a
acryloyl-CoA reductase activity is a
acyl-CoA dehydrogenase (NADP+) activity is a
all-trans-geranyl-geranyl diphosphate reductase activity is a
alpha-santonin 1,2-reductase activity is a
anthocyanidin reductase activity is a
arogenate dehydrogenase [NAD(P)+] activity is a
benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity is a
benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity is a
beta-nitroacrylate reductase activity is a
biliverdin reductase activity is a
biochanin-A reductase activity is a
but-1-en-3-one reductase activity is a
campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity is a
cinnamate reductase activity is a
cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity is a
cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity is a
cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity is a
cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity is a
cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity is a
cis-2,3-dihydrodiol DDT dehydrogenase activity is a
cis-2-enoyl-CoA reductase (NADPH) activity is a
cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity is a
cis-chlorobenzene dihydrodiol dehydrogenase activity is a
cis-dihydroethylcatechol dehydrogenase activity is a
citronellyl-CoA dehydrogenase activity is a
cortisone alpha-reductase activity is a
crotonaldehyde redutase activity is a
cucurbitacin delta23-reductase activity is a
cyclohexadienyl dehydrogenase activity is a
delta14-sterol reductase activity is a
delta24(24-1) sterol reductase activity is a
delta24-sterol reductase activity is a
dibenzothiophene dihydrodiol dehydrogenase activity is a
dihydrogeranylgeranyl-chlorophyll a reductase activity is a
dihydrogeranylgeranyl-PP reductase activity is a
dihydropyrimidine dehydrogenase (NADP+) activity is a
dihydrouracil dehydrogenase (NAD+) activity is a
divinyl chlorophyllide a 8-vinyl-reductase activity is a
enone reductase activity is a
enoyl-[acyl-carrier-protein] reductase (NADH) activity is a
enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity is a
enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity is a
enoyl-[acyl-carrier-protein] reductase activity is a
fumarate reductase (NADH) activity is a
furaneol oxidoreductase activity is a
geissoschizine dehydrogenase activity is a
geranylgeranyl diphosphate reductase activity is a
geranylgeranyl-chlorophyll a reductase activity is a
homofuraneol oxidoreductase activity is a
kynurenate-7,8-dihydrodiol dehydrogenase activity is a
lariciresinol reductase activity is a
maleylacetate reductase activity is a
menthone dehydrogenase activity is a
meso-tartrate dehydrogenase activity is a
N-ethylmaleimide reductase activity is a
NADPH-dependent curcumin reductase activity is a
NADPH-dependent dihydrocurcumin reductase activity is a
orotate reductase (NADH) activity is a
orotate reductase (NADPH) activity is a
phloroglucinol reductase activity is a
phosphatidylcholine desaturase activity is a
phthalate 3,4-cis-dihydrodiol dehydrogenase activity is a
phthalate 4,5-cis-dihydrodiol dehydrogenase activity is a
pimeloyl-CoA dehydrogenase activity is a
pinoresinol reductase activity is a
polyprenol reductase activity is a
precorrin-2 dehydrogenase activity is a
precorrin-6A reductase activity is a
prephenate dehydrogenase (NAD+) activity is a
prephenate dehydrogenase (NADP+) activity is a
progesterone 5-alpha-reductase activity is a
progesterone 5beta- reductase activity is a
protochlorophyllide reductase activity is a
pterocarpan reductase activity is a
tetrahydrogeranylgeranyl-chlorophyll a reductase activity is a
tetrahydrogeranylgeranyl-PP reductase activity is a
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity is a
trans-1,2-dihydrodiolphenanthrene dehydrogenase activity is a
trans-2-enoyl-CoA reductase (NAD+) activity is a
trans-2-enoyl-CoA reductase (NADPH) activity is a
trans-4-hexen-3-one reductase activity is a
trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity is a
trans-arachidon-2-enoyl-CoA reductase activity is a
trans-cerot-2-enoyl-CoA reductase activity is a
trans-docosan-2-enoyl-CoA reductase activity is a
trans-lignocero-2-enoyl-CoA reductase activity is a
very-long-chain enoyl-CoA reductase activity is a
xanthommatin reductase activity is a
zeatin reductase activity is a
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor is a
oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor is a
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor is a
peptidyl-oxazoline dehydrogenase activity is a
peptidyl-thiazoline dehydrogenase activity is a
phytoene dehydrogenase activity is a
propionyl-CoA dehydrogenase activity is a
protoporphyrinogen oxidase activity is a
quinaldate 4-oxidoreductase activity is a
quinoline 2-oxidoreductase activity is a
quinoline-4-carboxylate 2-oxidoreductase activity is a
steroid dehydrogenase activity, acting on the CH-CH group of donors is a
sterol 5-alpha reductase activity is a
sterol delta7 reductase activity is a
succinate dehydrogenase activity is a
thalian-diol desaturase activity is a
thiol-driven fumarate reductase activity is a
oxidoreductase activity, acting on the CH-NH group of donors is a
oxidoreductase activity, acting on the CH-NH2 group of donors is a
oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond is a
oxidoreductase activity, oxidizing metal ions is a
oxygen evolving activity is a
perchlorate reductase activity is a
phthalate dioxygenase reductase activity is a
pyrogallol hydroxytransferase activity is a
reduced coenzyme F420 dehydrogenase activity is a
reduced coenzyme F420 oxidase activity is a
reduced coenzyme F420:quinone oxidoreductase activity is a
selenate reductase activity is a
sphingosine hydroxylase activity is a
steroid dehydrogenase activity is a
sulfur oxygenase reductase activity is a
sulfur reductase activity is a
tetrachloroethene reductive dehalogenase activity is a
tetrahydrothiophene 1-oxide reductase activity is a
thyroxine 5'-deiodinase activity is a
thyroxine 5-deiodinase activity is a
trimethylarsine oxidase activity is a
tyramine-beta hydroxylase activity is a
uracil oxygenase activity is a
vinyl chloride reductive dehalogenase activity is a
violaxanthin de-epoxidase activity is a
thioredoxin reduction is a
pigment metabolic process is a
primary metabolic process is a
respiratory burst is a
secondary metabolic process is a
small molecule metabolic process is a
tartrate metabolic process is a
tyrocidine metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a