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Gene ontology
Version 2014-12-22
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Details for phosphatidylinositol 3-kinase activity
Gene ontology ID
GO:0035004
Definition
Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring
Synonyms
1. phosphoinositide 3-kinase activity
References
1. GOC: bf
2. PMID 10209156
3. PMID 9255069
4. Reactome: R-HSA-1433514 "Synthesis of PIP3 from PIP2 by PI3K"
5. Reactome: R-HSA-2045911 "BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3"
6. Reactome: R-HSA-9028519 "NTRK2-activated PI3K generates PIP3"
7. Wikipedia: Phosphoinositide 3-kinase
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular metabolic process is a
cellular lipid metabolic process is a
glycerolipid metabolic process is a
glycerophospholipid metabolic process is a
phosphatidylinositol metabolic process is a
phosphatidylinositol phosphorylation is a
phosphatidylinositol 3-kinase activity part of
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
negative regulation of phosphatidylcholine metabolic process is a
regulation of biological process is a
modulation of host virulence by virus is a
negative regulation of biological process is a
positive regulation of biological process is a
regulation of action potential is a
regulation of asexual reproduction is a
regulation of biomineralization is a
regulation of carbohydrate utilization is a
regulation of carbon utilization is a
regulation of cellular process is a
cell redox homeostasis is a
modulation by symbiont of host cellular process is a
regulation of actin filament-based process is a
regulation of binding of sperm to zona pellucida is a
regulation of cartilage condensation is a
regulation of cell activation is a
regulation of cell adhesion molecule production is a
regulation of cell aging is a
regulation of cell communication is a
regulation of cell cycle is a
regulation of cell death is a
regulation of cell differentiation is a
regulation of cell division is a
regulation of cell killing is a
regulation of cell population proliferation is a
regulation of cell wall organization or biogenesis is a
regulation of cellular component biogenesis is a
regulation of cellular component movement is a
regulation of cellular component organization is a
regulation of cellular localization is a
regulation of cellular metabolic process is a
regulation of cellular pH reduction is a
regulation of cellular response to alcohol is a
regulation of cellular response to alkaline pH is a
regulation of cellular response to drug is a
regulation of cellular response to gamma radiation is a
regulation of cellular response to growth factor stimulus is a
regulation of cellular response to insulin stimulus is a
regulation of cellular response to macrophage colony-stimulating factor stimulus is a
regulation of cellular response to manganese ion is a
regulation of cellular response to oxidopamine is a
regulation of cellular response to stress is a
regulation of cellular response to testosterone stimulus is a
regulation of cellular response to thapsigargin is a
regulation of cellular response to tunicamycin is a
regulation of cellular response to very-low-density lipoprotein particle stimulus is a
regulation of cellular response to X-ray is a
regulation of chromosome segregation is a
regulation of conjugation is a
regulation of cytolysis is a
regulation of establishment or maintenance of cell polarity is a
regulation of horizontal cell localization is a
regulation of membrane depolarization is a
regulation of microtubule-based process is a
regulation of myelination is a
regulation of peroxidase activity is a
regulation of phenotypic switching is a
regulation of protein folding is a
regulation of response to cell cycle checkpoint signaling is a
regulation of secretion by cell is a
regulation of single-species biofilm formation is a
regulation of stomatal movement is a
regulation of transmembrane transport is a
regulation of transposition is a
regulation of vacuolar transport is a
regulation of vesicle-mediated transport is a
signal transduction is a
apoptotic signaling pathway is a
bile acid signaling pathway is a
calmodulin dependent kinase signaling pathway is a
carbohydrate mediated signaling is a
cell surface receptor signaling pathway is a
chloroplast-nucleus signaling pathway is a
dopamine receptor signaling pathway is a
endoplasmic reticulum unfolded protein response is a
ER-nucleus signaling pathway is a
extracellular ATP signaling is a
G protein-coupled receptor signaling pathway is a
hormone-mediated signaling pathway is a
hydrogen peroxide mediated signaling pathway is a
hypoxia-inducible factor-1alpha signaling pathway is a
immune response-regulating signaling pathway is a
intracellular receptor signaling pathway is a
intracellular signal transduction is a
endosomal signal transduction is a
hippo signaling is a
inositol lipid-mediated signaling is a
MAPK cascade is a
ERK1 and ERK2 cascade is a
ERK5 cascade is a
MAP kinase activity part of
MAPK cascade involved in ascospore formation is a
MAPK cascade involved in axon regeneration is a
MAPK cascade involved in innate immune response is a
stress-activated MAPK cascade is a
phosphorelay signal transduction system is a
PKR signal transduction is a
protein kinase A signaling is a
protein kinase B signaling is a
protein kinase C signaling is a
protein kinase D signaling is a
RAM/MOR signaling pathway is a
second-messenger-mediated signaling is a
signal transduction by p53 class mediator is a
signal transduction in response to DNA damage is a
small GTPase mediated signal transduction is a
stress-activated protein kinase signaling cascade is a
TOR signaling is a
TRAF-mediated signal transduction is a
ligand-gated ion channel signaling pathway is a
lipoprotein particle mediated signaling is a
mitochondria-nucleus signaling pathway is a
necroptotic signaling pathway is a
neuronal signal transduction is a
osmosensory signaling pathway is a
pattern recognition receptor signaling pathway is a
peptidoglycan recognition protein signaling pathway is a
phototransduction is a
postsynaptic signal transduction is a
presynaptic signal transduction is a
receptor ligand activity part of
red or far-red light signaling pathway is a
regulation of blood pressure by chemoreceptor signaling pathway is a
regulation of floral organ abscission by signal transduction is a
salicylic acid mediated signaling pathway is a
serotonin receptor signaling pathway is a
signal transduction by conformational transition is a
signal transduction by protein phosphorylation is a
signal transduction in absence of ligand is a
signal transduction involved in cellular response to ammonium ion is a
signal transduction involved in filamentous growth is a
signal transduction involved in regulation of gene expression is a
sphingolipid mediated signaling pathway is a
regulation of circadian rhythm is a
regulation of developmental pigmentation is a
regulation of developmental process is a
regulation of estrogen receptor binding is a
regulation of growth is a
regulation of guanyl-nucleotide exchange factor activity is a
regulation of hemostasis is a
regulation of immune system process is a
regulation of interspecies interactions between organisms is a
regulation of localization is a
regulation of locomotion is a
regulation of membrane hyperpolarization is a
regulation of metabolic process is a
regulation of multi-organism process is a
regulation of multicellular organismal process is a
regulation of nitrogen utilization is a
regulation of phosphorus utilization is a
regulation of plasma lipoprotein particle levels is a
regulation of reproductive process is a
regulation of response to stimulus is a
regulation of signaling is a
regulation of sulfur utilization is a
regulation of biological quality is a
regulation of molecular function is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
bioluminescence is a
cellular alcohol metabolic process is a
cellular aldehyde metabolic process is a
cellular alkane metabolic process is a
cellular alkene metabolic process is a
cellular alkyne metabolic process is a
cellular aromatic compound metabolic process is a
cellular biosynthetic process is a
cellular carbohydrate metabolic process is a
cellular catabolic process is a
cellular ketone body metabolic process is a
cellular ketone metabolic process is a
cellular lipid metabolic process is a
cellular lipid biosynthetic process is a
ether lipid metabolic process is a
fatty acid metabolic process is a
glycerolipid metabolic process is a
acylglycerol metabolic process is a
glycerophospholipid metabolic process is a
lysobisphosphatidic acid metabolic process is a
phosphatidic acid metabolic process is a
phosphatidylcholine metabolic process is a
phosphatidylethanolamine metabolic process is a
phosphatidylglycerol metabolic process is a
phosphatidylinositol metabolic process is a
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process is a
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process is a
GPI anchor metabolic process is a
phosphatidylinositol 5-phosphate metabolic process is a
phosphatidylinositol acyl-chain remodeling is a
phosphatidylinositol dephosphorylation is a
phosphatidylinositol phosphorylation is a
phosphatidylinositol 3-kinase activity part of
phosphatidylinositol bisphosphate kinase activity part of
phosphatidylinositol kinase activity part of
phosphatidylinositol phosphate kinase activity part of
phosphatidylserine metabolic process is a
platelet activating factor metabolic process is a
isoprenoid metabolic process is a
lipid modification is a
membrane lipid metabolic process is a
neutral lipid metabolic process is a
oligosaccharide-lipid intermediate biosynthetic process is a
phospholipid metabolic process is a
sulfolipid metabolic process is a
cellular macromolecule metabolic process is a
cellular metabolic compound salvage is a
cellular modified amino acid metabolic process is a
cellular nitrogen compound metabolic process is a
cellular organohalogen metabolic process is a
chemosynthesis is a
cofactor metabolic process is a
drug metabolic process is a
generation of precursor metabolites and energy is a
heterocycle metabolic process is a
hydroperoxide metabolic process is a
metabolite repair is a
mucilage metabolic process is a
one-carbon metabolic process is a
organic acid metabolic process is a
organometal metabolic process is a
phosphorus metabolic process is a
photosynthesis is a
prenylation is a
reactive oxygen species metabolic process is a
selenium compound metabolic process is a
sulfur compound metabolic process is a
toxin metabolic process is a
xenobiotic metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a