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Gene ontology
Version 2014-12-22
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Details for MAP kinase activity
2.7.11.24
Gene ontology ID
GO:0004707
Definition
Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli
References
1. GOC: ma
2. ISBN 0198547684
3. EC 2.7.11.24
4. KEGG: R00162
5. MetaCyc 2.7.11.24-RXN
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