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Gene ontology
Version 2014-12-22
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Details for 25-hydroxycholesterol 7alpha-hydroxylase activity
1.14.14.29
Gene ontology ID
GO:0033783
Definition
Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O
Synonyms
1. 25-hydroxycholesterol 7alpha-monooxygenase activity
2. cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity
3. CYP7B1
4. CYP7B1 oxysterol 7alpha-hydroxylase activity
References
1. EC 1.14.14.29
2. MetaCyc RXN-7980
3. MetaCyc RXN-7981
4. RHEA: 19041
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